Rare-earth double-doped functional nanocomposite material and preparation method thereof

Abstract

The invention provides a rare-earth double-doped functional nanocomposite material and a preparation method thereof. The method comprises the process that a sodium hydroxide solution is added into a rare earth ion solution containing gadolinium chloride, europium chloride and terbium chloride; stirring reaction is performed to obtain a colloidal transparent solution; the solvents of the rare earthion solution and the sodium hydroxide solution are polylol, so that the colloidal transparent solution and coating liquid react under heating condition; transparent suspension with a core-shell structure is obtained; the coating liquid contains 3-aminopropyl triethoxysilane, tetraethyl orthosilicate, water, triethylamine and polylol; impurities in the transparent suspension with the core-shell structure are removed; vacuum drying is performed; then, calcination is performed to obtain a product. Tb<3+> and Eu<3+> lanthanide ions are doped into a Gd2O3 substrate; crystal nucleuses are subjectedto organic polysiloxane layer coating; the problem of low Gd2O3 single-doped fluorescence intensity is solved; the biocompatibility of the material is also improved; the fluorescence lifetime is prolonged.

Description

technical field [0001] The invention relates to the field of nanometer materials, in particular to a rare earth double-doped functional nanocomposite material and a preparation method thereof. Background technique [0002] Traditional bioprobes are based on radioisotope labeling and fluorophore labeling. The biggest disadvantage of labeling with radioactive isotopes is that there are radioactive pollutants, which are harmful to human health. The disadvantages of using fluorescent dyes as labels are: in order to facilitate the attachment of biomolecules, functionalized fluorophores must be synthesized separately; the sensitivity of fluorophore labels is not high, and identifiable signals can only be obtained at relatively high concentrations ; and fluorescent markers are prone to photobleaching. [0003] The size and microstructure of rare earth luminescent materials with special morphology have an important influence on their properties and applications. Therefore, rare ea...

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Problems solved by technology

[0006] The first object of the present invention is to provide a kind of preparation method of rare earth double-doped functional nanocomposite material, and this method is to Gd 2 o 3 Incorporation of Tb into the matrix 3+ 、Eu 3+ Two kinds of lanthanide ions, and wrapping the crystal nucleus with an organopolysiloxane layer, which not only solves the problem of Gd 2 o 3 The problem of low fluorescence intensity of single doping improves the biocompatibility of the material and prolongs the fluorescence lifetime

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