Anti-aging composition comprising NADH and ceramide, skincare product as well as preparation method and application thereof
A ceramide, anti-aging technology, applied in the field of skin care products, can solve the problems of poor stability of antioxidants, exaggerated claims, accelerated skin aging, etc., and achieves the effect of simple preparation process, safe and effective production cost
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[0026] Among them, NADH is reduced nicotinamide adenine dinucleotide (reduced nicotinamide adenine dinucleotide), also known as reduced coenzyme I, with a chemical formula of C21H27N7O14P2 and a molecular weight of 663.43. Its oxidized form is nicotinamide adenine dinucleotide (oxidized nicotinamide adenine dinucleotide, abbreviated as NAD), which plays the role of transferring hydrogen and electrons in biological oxidation, and plays an important role in maintaining cell growth, differentiation and energy metabolism. It participates in the metabolism, rhythm, pathological changes, aging and apoptosis of body cells and other life processes. The current NADH preparation method includes the following steps: extracting the crude extract of nicotinamide riboside adenylyltransferase or its pure enzyme; immobilizing the crude extract of recombinant nicotinamide ribosyl adenylyltransferase or its pure enzyme; The recombinant nicotinamide riboside adenylyltransferase catalyzes the pre...
Embodiment 1
[0041] (1) Raw materials: 50 parts by weight of NADH, 25 parts by weight of ceramide, 15 parts by weight of bird's nest acid, 30 parts by weight of ginsenoside, 15 parts by weight of icariin, 7 parts by weight of baohuoside I, 10 parts by weight of s-adenoside Glycoside methionine, 20 parts by weight of phosphatidylserine, 5 parts by weight of NMN, and 50 parts by weight of PPD.
[0042] (2) Excipients: 50 parts by weight of glycerin, 50 parts by weight of deionized water, 25 parts by weight of hyaluronic acid, 50 parts by weight of surfactant, 50 parts by weight of pH regulator, and 50 parts by weight of antioxidant.
[0043] (3) preparation method, comprises the steps:
[0044] (a) Pass each component of the raw materials and auxiliary materials through a 30-80 mesh sieve, so that the particle size distribution is uniform, the fluidity is better, and it is kept dry. Proportionally weigh the screened raw materials, add relevant auxiliary materials, and mix evenly;
[0045] (...
Embodiment 2
[0048] (1) Raw materials: 1 part by weight of NADH, 4 parts by weight of ceramide, 1 part by weight of bird's nest acid, 5 parts by weight of ginsenoside, 4 parts by weight of icariin, 6 parts by weight of baohuoside I, 2 parts by weight of s-glandin Glycoside methionine, 8 parts by weight of phosphatidylserine, 2 parts by weight of NMN, and 40 parts by weight of PPD.
[0049] (2) Excipients: 1 part by weight of glycerin, 3 parts by weight of deionized water, 1 part by weight of hyaluronic acid, and an appropriate amount of 1 part by weight of surfactant, 1 part by weight of pH regulator, and 1 part by weight of antioxidant.
[0050] (3) Preparation method:
[0051] a. Pass each component of raw materials and auxiliary materials through a 30-80 mesh sieve, so that the particle size distribution is uniform, the fluidity is better, and it is kept dry. Proportionally weigh the screened raw materials, add relevant auxiliary materials, and mix evenly;
[0052] b. Add water and sti...
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