Organic silicon modified TPU medical catheter and preparation method thereof

Abstract

The invention belongs to the technical field of polyurethane elastomers, and particularly relates to an organic silicon modified TPU medical catheter and a preparation method thereof. The organic silicon modified TPU medical catheter comprises a TPU material and a polyvinylpyrrolidone coating, wherein the TPU material is prepared from the following raw materials in parts by mass: 49 to 70 parts oforganic silicon modified polyol, 23 to 40 parts of diisocyanate, 3 to 12 parts of a chain extender, 0.02 to 0.04 part of a catalyst and 0.1 to 0.5 part of a coupling agent. The organic silicon modified TPU medical catheter has excellent mechanical performance and biocompatibility and high low-temperature flexibility, water resistance and hydrophilic lubricity, participates in a reaction in initial raw material synthesis, and avoids the problem of migration. The invention further provides a preparation method which is simple in process and easy and convenient to operate.

Description

technical field [0001] The invention belongs to the technical field of polyurethane elastomers, and in particular relates to an organosilicon-modified TPU medical catheter and a preparation method thereof. Background technique [0002] At present, most of the raw materials used in medical catheters in my country are soft polyvinyl chloride, but the residual vinyl chloride monomer in the material and the plasticizer added to it will cause great harm to the human body. Compared with other medical materials such as PE, PP, TPE, PVC and silicone rubber, TPU has good biocompatibility, no distortion, no allergic reaction, good blood compatibility and antithrombotic performance, and does not damage blood components. It has excellent stability, mechanical and processing properties, and the material does not contain plasticizers, is easy to incinerate, does not release corrosive substances and other dangerous chemicals, and is widely used in the medical industry. [0003] Medical ca...

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Problems solved by technology

[0004] Patent CN 109135293 A discloses a dynamic vulcanized silicone rubber / thermoplastic polyurethane elastomer and its preparation method. Silicon rubber and TPU are used for dynamic vulcanization, which is prepared in two steps, high temperature kneading granulation and dynamic vulcanization; the operation is complicated , it is necessary to develop special equipment for dynamic vulcanization and precisely control the dynamic vulcanization process. It is easy for the rubber to be difficult to shear and break, and to form tiny dispersed phase particles. It is difficult to achieve the ideal dispersion of silicone rubber in the TPU matrix, resulting in insufficient microscopic morphology of the product. The mechanical properties and elasticity are poor, the blending modification method can only improve the surface properties, the silicone is easy to migrate, and the hydrophobicity and environmental protection properties of the material are not suitable for medical interventional catheters

[0005] Patent CN201510740025X discloses a silicone-modified thermoplastic polyurethane elastomer and its preparation method, using macromolecular diol, hydroxyalkyl-terminated polydimethylsiloxane, diisocyanate, small molecule chain extender, Catalysts, antioxidants, and UV absorbers to synthesize polyurethane elastomers; it directly adds silicone during the TPU synthesis process. Although the high and low temperature resistance and mechanical properties of polyurethane elastomers are enhanced, silicones are less compatible with other components. Poor, easy to migrate during use, and the addition of silicone further enhances the hydrophobicity of the TPU material, which is not suitable for medical interventional catheters

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