Lignan compound in herba portulacae and extraction and separation method and application of lignan compound

A technology of lignans and separation method, which is applied in the field of extraction and separation of lignans, can solve the problems of low structural novelty and the like, and achieves the effects of environmental protection of the process method, simple and fast operation method
CN112300104AActive Publication Date: 2021-02-02LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
Publication Date
2021-02-02

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Abstract

The invention relates to the field of traditional Chinese medicine extraction and separation, in particular to a new compound extracted, separated and identified from a purslane medicinal material andan extraction and separation method and application thereof. The invention provides a lignan compound olealignan A extracted from portulaca oleracea and an extraction and separation method and application thereof. The ester compound is prepared by sequentially adopting alcohol decoction extraction, silica gel column chromatography, polyamide column chromatography, ODS medium-pressure column and Sephadex LH-20 purification and liquid phase separation. The extraction and separation method is simple, convenient, quick and environment-friendly, and the compound separated by the method is relatively high in purity and pharmacological experiments prove that the obtained compound has anti-tumor and anti-cholinesterase effects so that the lignan compound olealignan A extracted from purslane and the salt and derivative thereof can be used as natural products to develop new traditional Chinese medicine, and have a wide medical application prospect.
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Description

technical field

[0001] The invention relates to the field of extraction and separation of traditional Chinese medicines, in particular to a new compound extracted, separated and identified from purslane medicinal material and its extraction and separation method and application, specifically a lignan compound extraction and separation method and its application. Background technique

[0002] Purslane (Portulaca oleracea L.), also known as amaranth, longevity vegetable, ant vegetable, is an annual herb of the family Portulacaceae. Purslane is widely distributed and rich in resources. It is one of the 78 wild plants with the same origin of medicine and food stipulated by the Ministry of Health of my country. Purslane is recorded in the 2015 edition of "Pharmacopoeia of the People's Republic of China". It has the functions of clearing heat and detoxifying, cooling blood and stopping bleeding, and stopping dysentery. , hemorrhoids, metrorrhagia, etc.

[0003] Modern pharmacolo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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