Quaternized abalone antibacterial peptide gel as well as preparation method and application thereof

Abstract

The invention provides quaternized abalone antibacterial peptide gel as well as a preparation method and application thereof. The gel is prepared from quaternized abalone antibacterial peptide powder,thyme essential oil, sodium alginate, propylene glycol alginate and water. According to the quaternized abalone antibacterial peptide gel as well as the preparation method and application thereof, the abalone polypeptide extracted by adopting an enzymolysis technology and a membrane separation technology is higher in degree and fewer in impurities, the quaternized abalone antibacterial peptide powder is obtained through quaternization reaction, and then the quaternized abalone antibacterial peptide powder is added into a gel matrix to be uniformly mixed. The quaternized abalone antibacterialpeptide gel disclosed by the invention is high in compatibility of all the components, a formed polymer network can effectively wrap quaternized abalone antibacterial peptide, and the quaternized abalone antibacterial peptide gel is mild and non-irritant to skin and has a certain moisturizing effect; and in addition, the quaternized abalone antibacterial polypeptide gel has a relatively strong antibacterial effect and is not easy to generate drug resistance, so that a method and a route are provided for researching and developing a new antibacterial agent, and meanwhile, the quaternized abalone antibacterial polypeptide gel has a good application prospect in the fields of medicines and cosmetics.

Description

technical field [0001] The invention belongs to the technical field of deep processing of marine shellfish, and in particular relates to a quaternized abalone antimicrobial peptide gel and its preparation method and application. Background technique [0002] Abalone has rich nutritional value such as protein, polysaccharide, fatty acid, etc., which are biologically active substances beneficial to the human body, and protein accounts for more than 50% of the dry weight. Abalone peptides are a class of macromolecular substances with a wide range of biological activities. Many scholars have discovered and applied them in the field of health food because of their anti-tumor, anti-oxidation, and immune regulation functions. However, there are few studies on the antibacterial effects of abalone peptides. Even though relevant research shows that although abalone polypeptide has certain antibacterial function, its antibacterial effect is relatively weak and not enough for practical ...

AI Technical Summary

Problems solved by technology

[0004] Many antibiotics are added to commercially available antibacterial gels to achieve antibacterial effect. Long-term use of antibiotic-containing drugs will cause bacterial resistance, which may lead to bacterial infections without cure

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