Antibacterial peptide, composition containing antibacterial peptide and application

A composition and antimicrobial peptide technology, applied in the direction of medical preparations containing active ingredients, medical preparations with non-active ingredients, antibacterial drugs, etc., can solve the problem of rapid activity reduction, difficulty in preparation, poor activity stability, etc. problem, to achieve the effect of low hemolysis rate and good antibacterial activity
CN113307850AActive Publication Date: 2021-08-27WENZHOU UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
WENZHOU UNIVERSITY
Publication Date
2021-08-27

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Abstract

The invention relates to an antibacterial peptide, a composition containing the antibacterial peptide and application. The amino acid sequence of the antibacterial peptide is as shown in SEQ ID No. 1. The antibacterial peptide has antibacterial activity against microorganisms in the genus Staphylococcus, Streptococcus, Enterococcus, Micrococcus, Moraxella, Corynebacterium, Klebsiella, Enterobacter, Serratia, Proteus, Pseudomonas, Morgan morganella, Haemophilus, Flavomonas, Acinetobacter and Propionibacterium.
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Description

technical field

[0001] The present invention relates to an antimicrobial peptide, which is used in the treatment of blepharitis, hordeolum, dacryocystitis, conjunctivitis or sterility during operation. Background technique

[0002] Since the invention of antibiotics, humans have made great achievements in the control and treatment of microbial infections, but with the continuous use of antibiotics, microbial resistance has become a major problem in microbial infection control, so that some microorganisms can no longer be used. There are antibiotics to control. For example, in clinical drug treatment, vancomycin-resistant staphylococci, enterococci and other Gram-negative bacterial infection diseases have become clinical problems worldwide.

[0003] Antimicrobial peptides are a class of small-molecule polypeptides widely present in microorganisms, animals and plants. They have antimicrobial activity and are usually composed of 12 to 50 amino acid residues with a molecular we...

Claims

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