One-pot production process of methyl isopropyl ketone

Abstract

The invention discloses a one-pot production process of methyl isopropyl ketone, and relates to the field of chemical synthesis. The process comprises the following steps: adding a certain amount of butanone, palladium on carbon and a basic catalyst into a hydrogenation reaction kettle, after nitrogen and hydrogen are replaced until no air is left in the reaction kettle, increasing the pressure in the reaction kettle to a certain pressure by using hydrogen, and heating the materials in the reaction kettle to a temperature required by reaction; starting the reaction kettle for stirring, adding the formaldehyde aqueous solution into the hydrogenation reaction kettle, and controlling the reaction temperature and the reaction pressure at the same time; the addition time of the formaldehyde is controlled within 1-10 hours; and after the reaction is finished, pressing out the materials in the reaction kettle, layering, rectifying an organic layer, obtaining a finished product, and packaging. The method has the beneficial effects that the process flow can be shortened, the energy consumption and the equipment investment are reduced, and the wastewater amount is reduced; the reaction yield is improved, and safety and controllability are realized.

Description

Technical field [0001] The present invention relates mainly to the field of chemical synthesis, specifically a production process of methyl isopropyl ketone one-pot cooking. Background [0002] Methyl isopropylone, Chinese alias: 1,1-Dimethylacetone; 3-Methyl-2-butanone; 3-Methylbutanone; Isopropyl methyl ketone; 3-Methyl-2-butanone; Methyl isopropyl ketone; Methyl isopropyl ketone / 3-methyl-2-butanone; Methyl isopropyl methyl ketone / 3-methyl-2-butanone. English name: Methyl Isopropyl Ketone, EINECS: 209-264-3, CAS NO.: 563-80-4, molecular formula: C5H10O, molecular weight: 86.13, mainly used as a dye intermediate, and can be used in pharmaceutical, pesticide, textile, paint, mineral processing and other industries. [0003] The method of synthesizing methyl isopropyl ketone in the prior art, including butanone methanol method, butanone formaldehyde method and the like. Among them, the existing butanone formaldehyde method to synthesize methyl isopropyl ketone is generally for but...

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Problems solved by technology

[0004] (1) Since a large amount of polymers will be produced in the condensation reaction of this process, the product yield will be seriously affected;

[0005] (2) Due to the step-by-step reaction, more equipment is needed, resulting in a substantial increase in equipment investment;

[0006] (3) The reaction time is long, at least 10 hours or more;

[0007] (4) Since the condensation product is slightly soluble in water, the water layer needs to be extracted with toluene after stratification, so that there is a small amount of toluene in the sewage, which increases the cost of sewage treatment

[0008] Although there is a "one pot cooking" reaction method recorded in the literature, adding all the materials together will cause the disproportionation reaction between formaldehyde and sodium hydroxide, so that the sodium hydroxide will be consumed, resulting in the inability of the normal condensation reaction, even if there is a conversion reaction rate is very low

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