Self-growing artificial skin with antibacterial effect for burns and preparation method of self-growing artificial skin

Abstract

The invention provides self-growing artificial skin with an antibacterial effect for burns and a preparation method of the self-growing artificial skin. The preparation method comprises the following steps: step S1, preparing a bacterial cellulose membrane and drying the bacterial cellulose membrane; s2, preparing an iodophor solution of which the iodine content is 0.5-12wt%; and S3, putting the dried bacterial cellulose membrane into the iodophor solution in the step S2, and soaking for 12-48 hours to obtain the self-growing artificial skin with the antibacterial effect for burn. The bacterial cellulose membrane with the antibacterial effect, which is obtained by the technical scheme of the invention, still has a very high killing rate on escherichia coli, staphylococcus aureus, pseudomonas aeruginosa, bacillus subtilis, candida albicans and the like after 30 days, and can be used as artificial skin for treating burns. The artificial skin has excellent biocompatibility, biocompatibility and biological adaptability, has very good antibacterial performance, can provide a humid and low-oxygen environment for new skin growth, and has the effect of promoting wound healing.

Description

technical field [0001] The invention belongs to the technical field of medical dressings, in particular to a self-growing artificial skin with antibacterial effect for burns and a preparation method thereof. Background technique [0002] Among all kinds of disasters, fire is one of the most frequent and common major disasters that threaten the safety of people's lives and properties, and after a fire occurs, people are almost always burned, and the physical and psychological damage caused by burns is very serious. Huge, long treatment process and prone to infection. In addition to being caused by fire, burns also include damage caused by high-temperature objects or electrical energy, chemical substances (such as strong acids and alkalis), radioactive energy, and strong flashes acting on the body's skin surface. [0003] In addition to the destruction of skin and tissue, extensive burns can also cause a series of complex pathological and physiological changes throughout the ...

AI Technical Summary

Problems solved by technology

The disadvantages are: it is impossible to keep the wound moist, and the wound healing time is long; the fibers in the dressing are easy to fall off, causing foreign body reactions and affecting the healing; when the dressing is soaked, pathogens can easily pass through; Cause pain; when changing the dressing, it is easy to damage the new tissue; the workload of changing the dressing is heavy, etc.

At present, there have been reports on the preparation of artificial skin with antibacterial properties by loading nano-silver on BC film, but the preparation process is relatively complicated, and the size of the loaded nano-silver particles is difficult to control, which affects its antibacterial properties.