Transfusion of astragalus root amino acid and its preparing method

An amino acid, astragalus technology, applied in the direction of drug delivery, pharmaceutical formulations, plant raw materials, etc., can solve the problems of time-consuming, increase the workload of nurses, increase the chance of pollution, etc., and achieve stable and reliable products.

Inactive Publication Date: 2006-10-11
KUNMING ZIJIAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In actual operation, the injection is still added to the infusion before use. The problems of this usage are: increasing the workload of nurses, increasing the chance of pollution, time-consuming, and not conducive to the rescue of critically ill patients.
However, amino acid infusion is now basically only used as a nutritional support or supplement, and critically ill patients with cardiovascular and cerebrovascular diseases often need to be given timely drugs for promoting blood circulation and removing blood stasis, and at the same time need to infuse nutritional support agents

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Astragalus and eight kinds of amino acid infusion, formula (1000ml):

[0023] Astragalus extract 1.5ml (equivalent to 8g of raw medicine)

[0024] L-Isoleucine 3.82g L-Leucine 5.03g

[0025] L-Lysine Acetate 4.52g L-Methionine 2.34g

[0026] L-Phenylalanine 5.65g L-Threonine 2.78g

[0027] L-Tryptophan 1.0g L-Valine 3.98g

[0028] Mannitol 70g

[0029] Preparation process: under the condition of 10,000 grade and nitrogen protection, first dissolve a small amount of L-tryptophan in ~20ml of water for injection, and pay attention to make it completely dissolved, and set aside; add the prescription amount of astragalus extract to ~20ml Dissolve in water for injection, and pay attention to make it completely dissolved, filter, and set aside; then dissolve other amino acids in an appropriate amount of water for injection ~ 500ml, add the above-dissolved tryptophan solution and astragalus solution, add mannitol and dilute with water for injection to The required volume i...

Embodiment 2

[0031] Astragalus and eleven kinds of amino acid infusion, formula (1000ml):

[0032]Astragalus 1.5ml (equivalent to 8g of raw medicine)

[0033] L-Isoleucine 3.72g L-Leucine 5.00g

[0034] L-Lysine Acetate 4.32g L-Methionine 2.30g

[0035] L-Phenylalanine 5.60g L-Threonine 2.71g

[0036] L-Tryptophan 0.90g L-Valine 3.98g

[0037] L-Arginine Hydrochloride 5.10g L-Tyrosine 0.27g

[0038] L-Histidine 2.10g Sorbitol 60g

[0039] Preparation process: same as above (omitted). Can make 2 bottles of 500ml: 4g (original drug) of Astragalus eleven kinds of amino acid infusion finished product.

Embodiment 3

[0041] Astragalus and eighteen kinds of amino acid infusion, formula (1000ml):

[0042] Astragalus 2ml (equivalent to 12g of raw medicine)

[0043] L-Isoleucine 3.52g L-Leucine 4.80g

[0044] L-Lysine Acetate 4.12g L-Methionine 2.10g

[0045] L-Phenylalanine 5.22g L-Threonine 2.40g

[0046] L-Tryptophan 0.80g L-Valine 3.63g

[0047] L-Arginine Hydrochloride 4.90g L-Tyrosine 0.24g

[0048] L-Histidine 2.00g L-Alanine 1.95g

[0049] L-Proline 1.00g L-Serine 1.00g

[0050] Glycine 7.56g L-Cystine 0.10g

[0051] L-Glutamic Acid 0.75g L-Aspartic Acid 2.50g

[0052] Sorbitol 50.00g

[0053] Preparation process: same as above (omitted). Can make 2 bottles of 500ml: 6g (original drug) of Astragalus eighteen kinds of amino acid transfusion finished products.

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Abstract

The invention provides an astragalus amino acid transfusion, which contains biologically active astragalus and amino acids with nutrition and energy supplements, and is characterized in that each bottle of transfusion contains 2-10 g of astragalus equivalent to crude drugs, and the rest are amino acids or other pharmaceutical auxiliary materials. Astragalus is highly unstable in ordinary solutions, but in amino acid solutions with multiple comprehensive functions such as complexation, anti-oxidation, and shielding, the main active ingredients such as astragalus saponins are relatively stable (just like in the original plant) Therefore, the Astragalus amino acid infusion is stored at room temperature for 1 year. The product is stable, reliable, and non-irritating. Compared with the existing Astragalus injection, it has a stronger effect of invigorating qi and promoting yang, promoting blood circulation and removing blood stasis than the existing Astragalus injection.

Description

technical field [0001] The invention relates to an astragalus amino acid infusion solution which can replenish qi and blood and has biological activity on cardiovascular and cerebrovascular and its production method. Background technique [0002] Astragalus membranaceus is the dry root of Astragalus membranaceus (Fisch.) Bge.var.mongholicus (Bge) Hsiao] or Astragalus membrane pod [Astragalus membranaceus (Fisch.) Bge]. Sweet in nature and flavor, slightly warm, returns spleen, lung meridian. The main functions are to invigorate qi and promote yang, replenish qi and consolidate the surface, detoxify and promote muscle growth, diuresis and reduce swelling, and it is one of the most important drugs in qi invigorating medicines. Astragalus is widely used in various clinical departments such as internal medicine, surgery, gynecology, pediatrics, and facial features. In recent years, in the clinical practice of internal medicine, it has been found that Astragalus has remarkable e...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/481A61K9/08A61P3/02A61P9/10
Inventor 杨兆祥
Owner KUNMING ZIJIAN BIOTECH
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