Biological degradable macromolecule microspheres of carrying insulin and preparation method

A polymer microsphere, biodegradable technology, applied in the field of biodegradable polymer microspheres and preparation, to achieve the effects of sustained release, improved insulin release behavior, and uniform distribution
CN1562356AInactive Publication Date: 2005-01-12CHANGZHOU INST OF ENERGY STORAGE MATERIALS &DEVICES

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
CHANGZHOU INST OF ENERGY STORAGE MATERIALS &DEVICES
Publication Date
2005-01-12
Estimated Expiration
Not applicable · inactive patent

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Abstract

A diodegradable high-molecular microsphere carrying insulin is prepared through preparing the nanoparticles of insulin, preparing the mixed solution of different two polymers, and dual-layer coating of said insulin nanoparticles.
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Description

technical field

[0001] The invention relates to a biodegradable polymer microsphere loaded with insulin and a preparation method thereof. Background technique

[0002] Diabetes is a worldwide disease, mainly manifested as glucose metabolism disorder caused by endocrine disorders. The incidence of diabetes is increasing year by year, and it has become the third leading cause of death after cardiovascular disease and cancer.

[0003] There are two types of diabetes, one is insulin-dependent diabetes mellitus (IDDM), also known as type 1 diabetes, which mostly appears in children and young adults and can be attributed to a genetic factor or an abnormal immune mechanism As a result, almost no insulin is produced in the body. The other, non-insulin-dependent diabetes mellitus (NIDDM), also known as type 2 diabetes, is diabetes that often begins in middle age. The patient can secrete insulin, but its function cannot be performed normally.

[0004] Insulin is the drug of choice...

Claims

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