Pharmaceutical delivery system

a delivery system and drug technology, applied in the field of delivery systems, can solve the problems of not reliably demonstrating the ability to deliver active agents in a controlled manner, difficult to deliver active agents to this area for an extended period of time, and significant physical deformation of the vaginal cavity, so as to reduce adverse effects, increase the potential for systemic uptake, and effectively impact the life cycle
US20050095245A1Inactive Publication Date: 2005-05-05DRAGTEK CORP

Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
DRAGTEK CORP
Publication Date
2005-05-05
Estimated Expiration
Not applicable · inactive patent

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Abstract

A pharmaceutical formulation to treat vaginal conditions in a human patient comprises: at least one active agent; a modified release dosage form which provides extended release of the anti-infective agent upon vaginal administration to the patient; and wherein the formulation, when containing a total dose of the anti-infective agent of about 25 μg to about 500 mg based on the active agent will produce a plasma concentration versus time curve (ng / mL versus hours) having an area under the curve (AUC) of less than about 600 ng / mL.hr.
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Description

BACKGROUND OF THE INVENTION

[0001] 1. Field of the Invention

[0002] The present invention is directed to delivery systems, which stabilize surface active therapeutic agents, or those therapeutic agents which obtain surface active properties in a delivery system. These systems are suitable for use in the vaginal cavity, as well as other mucosal cavities of the body. The invention is additionally concerned with preparations demonstrating a modified, controlled, extended or sustained release of the active and / or therapeutic agent and a minimal number of administrations to produce efficacy upon administration of said delivery system.

[0003] 2. Description of the Related Art

[0004] One significant aspect of medicine is the treatment of the female reproductive system for the prevention, treatment, mitigation, diagnosis and cure of diseases and the prevention of conception. Usually, this involves the delivery of active agents to the vaginal cavity and its environs. Systems to affect the de...

Claims

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