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Emulsified composition

a technology of emulsified composition and composition, which is applied in the field of emulsified composition, can solve the problems of unsatisfactory water retention of preparations containing such ingredients, impaired good feeling upon use, and heavy weight of solid fat that constitutes -gel, etc., and achieves enhanced water retention, enhanced steric regularity, and improved skin conditions

Inactive Publication Date: 2014-04-10
KAO CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention is an emulsion composition that contains specific ingredients that form a uniform structure with high steric regularity. This results in enhanced water retention, allowing water to stay in the skin for a long time. This improves skin conditions and results in excellent skin permeability and long-lasting moistness when applied to the skin. Additionally, the composition forms a soft coating layer on the skin surface, which retains water in the interlayer space, enhancing skin protection.

Problems solved by technology

However, since the water content of an aqueous solution of a single ingredient is generally limited to the bound water level, a preparation containing such an ingredient attains unsatisfactory water retention.
In addition, although the aforementioned α-gel is expected to exhibit satisfactory water retention, solid fat that constitutes α-gel provides users a heavy feeling upon use.
Thus, when the amount of α-gel is simply increased to enhance water retention, a good feeling upon use is impaired (e.g., sticky feeling upon use).

Method used

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Examples

Experimental program
Comparison scheme
Effect test

examples 54 to 56

[0123]O / W emulsion compositions having formulations shown in Table 10 were produced through production method (2). The thus-produced emulsion compositions were subjected to X-ray structural analysis and evaluated in terms of remaining water content and film formability. The skin permeability of each composition and lasting of moist skin attained by each composition were assessed. The results are also shown in Table 10.

[0124]Emulsion compositions having the same formulations as those of Examples 54 to 56 were also produced through production method (1) (Examples 30, 3, and 5). The evaluation results thereof are also shown in Table 10.

Production Method (2)

[0125]Phase I ingredients (mixture containing ingredients (A) to (E)) were heated and mixed at 80 to 95° C. Under propeller-stirring (300 rpm), phase II ingredient (aqueous phase containing ingredient (F)), which had been heated to 80 to 95° C., was added to the phase I ingredients, to thereby form an emulsion. The emulsion was gradu...

example 57

Skin Lotion

[0126]In a manner similar to that employed in Examples 1 to 10, an O / W emulsion composition (skin lotion) having a formulation shown in Table 11 was produced. X-ray structural analysis of the composition was performed. Film formability, and skin permeability of the composition, and lasting of moist skin attained by the composition were assessed. The results are also shown in Table 11.

TABLE 11(Ingredients)(wt. %)Phase ID1-(2-Hydroxyethylamino)-3-0.2isostearyloxy-2-propanolDPhytosphingosine0.01CPseudo-ceramide*0.5CCERAMIDE 20.1BCetanol0.2AMonostrearyl glyceryl ether0.2Glycerin5.0PhaseFWaterbal.IIMethylparabenq.s.EXylitol1.0EErythritol1.0Hydroxyethylcellulose0.01Eucalyptus extract0.1Thujopsis dolabrata extract0.1Altheae extract0.1Seaweed extract0.1L-Glutamic acid0.1Total100((A) + (B)) / ((A) + (B) + (C))0.40(A) / ((A) + (B))0.50(E) / ((A) + (B) + (C))1.98X-ray structure analysisα-typeFilm formabilityAPermeation sensation8Lasting of moist skin8*N-(Hexadecyloxyhydroxypropyl)-N-hydro...

example 58

Milky Lotion

[0127]In a manner similar to that employed in Examples 1 to 10, an O / W emulsion composition (milky lotion) having a formulation shown in Table 12 was produced. X-ray structural analysis of the composition was performed. The film formability and skin permeability of the composition, and lasting of moist skin attained by the composition were assessed. The results are also shown in Table 12.

TABLE 12(Ingredients)(wt. %)Phase IDSodium polyoxyethylene(4) lauryl ether0.2phosphateDPolyoxyethylene(20) sorbitan monostearate0.3(HLB 14.9)CPseudo-ceramide*1.0CCERAMIDE 20.1BCetanol1.0ASorbitan monostearate0.2Squalane4.0Dimethylpolysiloxane5.0Glycerin10.0PhaseFWaterbal.IIDSodium methyl stearoyl taurate0.3Methylparabenq.s.Phenoxyethanolq.s.Sodium hydroxideq.s.Carboxyvinyl polymer0.2Xanthan gum0.1EErythritol1.0EMannitol0.51,3-Butanediol2.0Ginger extract0.1Yuzu extract0.1Total100((A) + (B)) / ((A) + (B) + (C))0.52(A) / ((A) + (B))0.17(E) / ((A) + (B) + (C))0.65X-ray structure analysisα-typeFilm...

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PUM

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Abstract

The emulsion composition of the present invention contains(A) 0.001 to 10 wt. % of an organic compound having two or more hydroxyl groups, an inorganic value of 220 to 450, and an organic value of 300 to 1,000;(B) 0.001 to 10 wt. % of an organic compound having one hydroxyl group, an inorganic value of 100 to 200, and an organic value of 280 to 700;(C) 0.001 to 10 wt. % of a compound represented by formula (2):wherein R1 is a C4 to C30 hydrocarbon group; Z is a methylene group, a methine group, or an oxygen atom; X1, X2, X3 is a hydrogen atom, a hydroxyl group, or an acetoxy group; X4 is a hydrogen atom, an acetyl group, or a glyceryl group; each of R2 and R3 a hydrogen atom, a hydroxyl group, a hydroxymethyl group, or an acetoxymethyl group; R4 is a C5 to C60 hydrocarbon group; and R5 is a hydrogen atom or a hydrocarbon group containing 1 to 30 carbon atoms in total;(D) 0.00012 to 10 wt. % of at least one compound selected from the group consisting of a nonionic surfactant having a polyoxyethylene group and an HLB of 10 or higher, an ionic surfactant, and a sphingosine salt;(E) 0.003 to 15 wt. % of at least one compound selected from the group consisting of a sugar alcohol selected from the group consisting of erythritol, threitol, xylitol, and mannitol, a disaccharide, and a trisaccharide; and(F) water.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application is a Continuation of U.S. application Ser. No. 13 / 382,298, filed Jan. 5, 2012, which is the National Stage of International Application No. PCT / JP2010 / 004414, filed Jul. 6, 2010, which claims priority to Japanese Patent Application No. 2009-159737, filed Jul. 6, 2009 and Japanese Patent Application 2009-159738, filed Jul. 6, 2009; of which all of the disclosures are incorporated herein by reference in their entireties.FIELD OF THE INVENTION[0002]The present invention relates to an emulsion composition which allows water to remain in the skin for a long period of time.BACKGROUND OF THE INVENTION[0003]α-Gel has a hydrate-type crystal structure, which is a lamellar structure. The intercellular lipid present in the horny layer (i.e., the outermost skin layer) generally has the α-gel structure, and prevents entry of outside substances into the skin as well as transepidermal water loss. Also, the intercellular lipid itself reta...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K8/68A61K8/34A61Q19/00A61K8/37
CPCA61K8/68A61Q19/00A61K8/342A61K8/37A61K8/06A61K8/345A61K8/41A61K8/60A61K8/86A61K8/375
Inventor ORITA, MASANORIYOSHIDA, TOMOKAZUUEYAMA, CHIHIRO
Owner KAO CORP
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