149 results about "Methine group" patented technology

A photoelectric conversion element is provided and includes: an electrically conductive thin layer; an organic photoelectric conversion layer; and a transparent electrically conductive thin layer. The organic photoelectric conversion layer contains: a compound represented by formula (I); and a fullerene or a fullerene derivative.In the formula, Z1 represents an atomic group necessary for forming a 5- or 6-membered ring, L1, L2 and L3 each independently represents an unsubstituted methine group or a substituted methine group, D1 represents an atomic group, and n represents an integer of 0 or more.

A curable composition containing a lake dye having an absorption maximum in the wavelength region of from 700 nm to 1100 nm and a thermosetting compound and / or a photo-setting compound; a solid imaging device installing therein a filter prepared using the curable composition; and a lake dye represented by the following formula (V): wherein L1 represents a methine chain composed of odd number(s) of methine group(s); A1 and A2 are each independently represents an alkyl group having a sulfo group; Y represents a cation necessary to balance a charge and selected from the group consisting of alkali earth metal ions (Mg2+, Ca2+, Ba2+, Sr2+), transition metal ions (Ag+, Fe+, Co2+, Ni2+, Cu2+, Zn2+) and (Al3+).

Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared spectral range. The cyanine compounds of Formula I are presented:wherein Q is a portion of a polymethine bridge selected from the group consisting of:Also included are bioconjugates of the compounds of Formula I, methods of labeling biomolecules with the compounds, and methods of imaging.

The invention relates to compounds of a general formula (I): wherein Ar<1>is an optionally-substituted aryl or heteroaromatic group; R<1 >is an optionally-substituted lower alkyl, lower alkenyl, lower alkynyl or cyclo-lower alkyl group, or is an aryl, aralkyl or heteroaromatic group optionally having a substituent; R<2>is a hydrogen atom, a lower alkyl group, a lower alkenyl group or a lower alkynyl group, or is an aryl, aralkyl or heteroaromatic group optionally having a substituent; R<3>is a hydrogen atom or a lower alkyl group; R<4>is a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkyl group or a group of -N(R<1k>)R<1m>; T and U are a nitrogen atom or a methine group, etc. The compounds of the invention have excellent Weel kinase-inhibitory effect and are therefore useful in the field of medicines, especially treatment of various cancers.

A lithographic printing plate precursor comprises an imageable layer comprising a free radically polymerizable component, an initiator composition capable of generating free radicals upon exposure to imaging infrared radiation, an infrared radiation absorbing dye that is defined by Structure (I) shown in the disclosure, which dyes comprise one or more ethylenically unsaturated polymerizable groups in an organic group that is attached to the methine chain. These infrared radiation absorbing dyes exhibit a reduced tendency to crystallize in the imageable layers in the presence of tetraaryl borate counter anions and therefore provide improved shelf life.

A subject matter of the invention is cyanine derivatives of formula:in which the dotted lines represent the atoms necessary for the formation of one or two fused aromatic rings, each ring comprising 5 or 6 carbon atoms;R1, R2, R3 and R4 represent, independently of one another: H; substituted or unsubstituted C1-C15 alkyl; C1-C6 alkoxy; (C2-C12)dialkylamino; C1-C6 alkoxycarbonyl; di(C2-C12)alkylamido; a substituted or unsubstituted aryl, arylalkyl or aryloxy group; a halogen atom; a nitro; an L1-W, L2-M, L2-A or L2-G group;R5 and R6 represent, independently of one another: substituted or unsubstituted C1-C15 alkyl; a substituted or unsubstituted aryl or arylalkyl group; an L1-W, L2-M, L2-A or L2-G group;X is chosen from: O, S or CR7R8; Y is chosen from: O, S or CR9R10;R7, R8, R9 and R10 independently represent: substituted or unsubstituted C1-C15 alkyl; substituted or unsubstituted aryl, arylalkyl or aryloxy; an L1-W, L2-M, L2-A or L2-G group;R7 and R8 and / or R9 and R10 can also together form a ring comprising 5 or 6 atoms or a heterocycle comprising 4 to 5 carbon atoms and an oxygen atom;B represents a polymethine bridge comprising 1 to 5 methine groups, said groups being in particular individually unsubstituted or substituted by a substituted or unsubstituted C1-C15 alkyl; a substituted or unsubstituted aryl, arylalkyl or aryloxy group; a nitro group; an L1-W, L2-M, L2-A or L2-G group;L1 and L2 are connecting arms; G is a reactive group; A is a coupling agent; M is a conjugated molecule, W is a phosphate or phosphonate ester (preferably diester), with the proviso that the cyanine derivative comprises at least one L1-W group and at least one L2-A, L2-G or L2-M group.

A near infrared fluorescent contrast agent which is excellent in permeability in a living tissue and enables specific imaging of tumor and / or blood vessel, comprising a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R7, and R8 represent a C1-C10 alkyl group or the like; R3, R4, R5, R6, R9, R10, R11, and R12 represent a hydrogen atom, a C1-C6 alkyl group, an aryl group or the like; X1 and X2 represent a C1-C15 alkyl group or an aryl group and X1 and X2 in total have 0 to 4 carboxyl groups; m1, m2, and m3 represents 0 or 1; L1 to L7 independently represent a methine group; M represents a hydrogen atom, a metal, or a quaternary ammonium salt; and n represents an integer of 1 to 7 necessary for neutralizing charge.

Provided is an organic electroluminescent device (organic EL device), in which the luminous efficiency of the device is improved, driving stability is sufficiently ensured, and the construction of the device is simple. This organic EL device is an organic electroluminescent device, including a light-emitting layer between an anode and a cathode laminated on a substrate, in which the light-emitting layer contains a phosphorescent light-emitting dopant and an indolocarbazole compound as a host material. Examples of the indolocarbazole compound include a compound represented by the following formula (1). It should be noted that in the formulae: a ring A and a ring B are represented by the formulae (1a) and (1b), respectively; Ar's each represent an aromatic hydrocarbon group or an aromatic heterocyclic group; R's each represent a hydrogen atom, an alkyl group, or a cycloalkyl group; X represents a methine group or a nitrogen atom; A represents an aromatic hydrocarbon group, an alkyl group, a cycloalkyl group, or a group represented by the formula (1c); and n represents 0 or 1.

A crosslinkable composition including a component A with at least 2 acidic protons C—H in activated methylene or methine groups (the RMA donor group), and a component B with at least 2 activated unsaturated groups (the RMA acceptor group), and a catalyst system C that contains, or is able to generate a basic catalyst capable of activating the RMA reaction between components A and B, characterised in that the cross-linkable composition further includes an X—H group containing component D that is also a Michael addition donor reactable with component B under the action of catalyst C, wherein X is N, P, O, S or wherein X is C as part of an acidic methyl (CH3) group. A component D and catalyst additive mixtures for the manufacture of RMA crosslinkable composition.

The present invention relates to a crosslinkable polymer composition comprising reactive components A and B each comprising at least 2 reactive groups wherein the at least 2 reactive groups of component A are acidic protons (C—H) in activated methylene or methine groups and the at least 2 reactive groups of component B are activated unsaturated groups (C═C) to achieve crosslinking by Real Michael Addition (RMA), wherein the component A is a malonate containing component and wherein components A and B react on drying of the crosslinkable polymer composition by deblocking of latent base catalyst C by evaporation of carbon dioxide, which latent base crosslinking catalyst, is a substituted carbonate salt according to formula 1wherein X+ represents a non acidic cation and wherein R is hydrogen, alkyl, aryl or aralkyl group.

Disclosed is a photosensitive composition for volume hologram recording which shows excellent interference fringe record and a volume hologram recording medium having lighter weight and excellent storage stability. The invention is directed to a volume hologram recording photosensitive composition comprising: (a) a compound having at least one active methylene group in one molecule or a compound having at least two active methine groups in one molecule; (b) a compound containing in one molecule two or more groups which are nucleophilicly added by a carbanion generating from an active methylene group or an active methine group; (c) a Michael-reaction catalyst; (d) a photopolymerizable compound; and (e) a photopolymerization initiator composition.

A composition having excellent transparency, flexibility, rubber elasticity, thermal resistance, impact resistance, abrasion resistance and the like, a composition having excellent rigidity and impact resistance as well as excellently balanced in whitening resistance, abrasion resistance and heat sealability, and a composition having excellent rubbery properties, thermal resistance, abrasion resistance and flexibility are provided. A composition comprising a specific propylene•α-olefin copolymer for which, in a signal chart measured by 13C-NMR and predetermined such that the peak present at the highest magnetic field among the signals originating from CH (methine) of the constituent unit derived from an α-olefin having 4 to 20 carbon atoms is to be at 34.4 ppm, an absorption intensity A at about 22.0 to 20.9 ppm and an absorption intensity B at about 19.0 to 20.6 ppm satisfy the following relational expressions (i) and (ii) with respect to an absorption intensity C at about 19.0 to 22.0 ppm, which is assignable to propylene methyl: (A / C)×100≦8  (i), and (B / C)×100≧60  (ii), a molded product thereof, and the α-olefin-based copolymer are provided.

This invention relates to a method of treating cancer, and particularly a method including the steps of administering to a mammal in need of such treatment, either simultaneously or sequentially, (i) a compound selected from a paclitaxel and docetaxel, and (ii) a compound of the formula or a pharmaceutically acceptable salt or ester thereof; wherein R1, R2 and R3 are each independently selected from the group consisting of H, C1-C6 alkyl, halogen, CF3, CN, NO2, NH2, OH, OR, NHCOR, NHSO2R, SR, SO2R or NHR, wherein each R is independently C1-C6 alkyl optionally substituted with one or more substituents selected from hydroxy, amino and methoxy, and wherein each of R1, R2 and R3 may be present at any of the available positions 1 to 8; and wherein in each of the carbocyclic aromatic rings in formula (I), up to two of the methine (-CH=) groups may be replaced by an aza (-N=) group; and wherein any two of R1, R2 and R3 may additionally together represent the group -CH =CH.CH =CH-, such that this group, together with the carbon or nitrogen atoms to which it is attached, forms a fused 6 membered aromatic ring.

An RMA crosslinkable composition having at least one crosslinkable component including reactive components A and B each including at least 2 reactive groups, the at least 2 reactive groups of component A being acidic protons (C—H) in activated methylene or methine groups and the at least 2 reactive groups of component B are activated unsaturated groups (C═C) and a base catalyst (C) which reactive components A and B crosslink by Real Michael Addition (RMA) reaction under action of the base catalyst, characterised in that the at least one crosslinkable component including reactive components A and B in the composition have a total hydroxy number of less than 60, preferably less than 40 and more preferably less than 20 mg KOH / g solids. Further, specific resins A and B having a low hydroxy number for use in RMA cross-linkable compositions and a process for the manufacture thereof.

Disclosed is a compound represented by the following formula (I): wherein Z1 represents an atomic group necessary to form a 5- or 6-membered nitrogen-containing heterocyclic ring; Z2 represents an atomic group necessary to form a 5- or 6-membered heterocyclic ring, Z2 may further be substituted, or may be condensed with a hetero ring of a benzene ring; R1 represents a hydrogen atom, a halogen atom, a mercapto group, an alkyl group, an alkenyl group, an aryl group, an alkylthio group, an alkenylthio group, or an arylthio group; L1 and L2 each represents a methine group; p1, represents 0 or 1; V1 represents a substituent; and n represents 0, 1 or 2, and when n represents 2, a plurality of V1 may be the same or different.

A near-infrared absorptive image-forming composition, which contains a dye of formula (I):wherein L1 is a methine chain composed of 7 methine groups, and L1 may have a substituent but the substituent is not an amino group; R1, R2 and A each independently are an alkyl or cycloalkyl group, which may be substituted; B is a group of atoms necessary for forming an aromatic hydrocarbon ring or aromatic heteroring, and the ring formed with B may be substituted; Y is a cation necessary for keeping the charge balance in the molecule, but Y may not be present when Y is unnecessary for the charge balance; and R1 and R2 may bond to each other, to form a ring; an ink and an electrophotographic toner, each containing the composition; and an inkjet-recording method, an electrophotographic-recording method, and a near-infrared-ray-reading method.

The present invention relates to a radiation-sensitive mixture which contains an acrylate or methacrylate monomer and / or oligomer capable of free radical polymerization and having at least two acrylate and / or methacrylate groups and at least one photooxidizable group, a photoinitiator, an organic polymeric binder and a heptamethinecyanine dye acting as an IR-absorbing dye. It furthermore relates to a recording material comprising a substrate and a photopolymerizable layer and a process for the production of a printing plate from this recording material. The recording material is distinguished by suitable photosensitivity.

A near infrared fluorescent contrast agent which is excellent in permeability in a living tissue and enables specific imaging of tumor and / or blood vessel, comprising a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R7, and R8 represent a C1-C10 alkyl group or the like; R3, R4, R5, R6, R9, R10, R11, and R12 represent a hydrogen atom, a C1-C6 alkyl group, an aryl group or the like; X1 and X2 represent a C1-C15 alkyl group or an aryl group and X1 and X2 in total have 0 to 4 carboxyl groups; m1, m2, and m3 represents 0 or 1; L1 to L7 independently represent a methine group; M represents a hydrogen atom, a metal, or a quaternary ammonium salt; and n represents an integer of 1 to 7 necessary for neutralizing charge.

The present invention relates to a compound that has URAT1 inhibitory action, and a URAT1 inhibitor, a blood uric acid level-reducing agent and a pharmaceutical composition comprising the compound. More specifically, the present invention relates to a compound represented by Formula (I) below.[in the formula,R1 is -Q1-A1 and the like; is a double bond or a single bond; when is a double bond, W1 is a nitrogen atom or a group represented by the general formula: ═C(Ra)—, and W2 is a nitrogen atom or a group represented by the general formula: ═C(Rb)—; when is a single bond, W1 is a group represented by the general formula: —C(Raa)(Rab)— or a group represented by the general formula: —(C═O)—, and W2 is a group represented by the general formula: —C(Rba)(Rbb)—, a group represented by the general formula: —(C═O)— or a group represented by the general formula: —N(Rbc)—; W3, W4 and W5 are each independently a nitrogen atom or a methine group and the like that may have a substituent; X is a single bond, an oxygen atom and the like; Y is a single bond or (CRYiRYi′)n; and Z is a hydroxyl group or COOR2 and the like.

An RMA crosslinkable composition for making thick coating layers having at least one crosslinkable component comprising reactive components A and B each including at least 2 reactive groups wherein the at least 2 reactive groups of component A are acidic protons (C—H) in activated methylene or methine groups, and the at least 2 reactive groups of component B are activated unsaturated groups (C═C), to achieve crosslinking by Real Michael Addition reaction, the composition further including a base catalyst (C), an X—H group containing component (D) that is also a Michael addition donor reactable with component B under the action of catalyst C, wherein X is C, N, P, O or S and a sag control component (E). A crosslikable composition is also disclosed for preparing thick coating layers having a dry thickness of at least 70 mu having a surface appearance and hardness of the resulting cured composition.

A curable composition containing a lake dye having an absorption maximum in the wavelength region of from 700 nm to 1100 nm and a thermosetting compound and / or a photo-setting compound; a solid imaging device installing therein a filter prepared using the curable composition; and a lake dye represented by the following formula (V):wherein L1 represents a methine chain composed of odd number(s) of methine group(s); A1 and A2 are each independently represents an alkyl group having a sulfo group; Y represents a cation necessary to balance a charge and selected from the group consisting of alkali earth metal ions (Mg2+, Ca2+, Ba2+, Sr2+), transition metal ions (Ag+, Fe+, Co2+, Ni2+, Cu2+, Zn2+) and (Al3+).

The emulsion composition of the present invention contains(A) 0.001 to 10 wt. % of an organic compound having two or more hydroxyl groups, an inorganic value of 220 to 450, and an organic value of 300 to 1,000;(B) 0.001 to 10 wt. % of an organic compound having one hydroxyl group, an inorganic value of 100 to 200, and an organic value of 280 to 700;(C) 0.001 to 10 wt. % of a compound represented by formula (2):wherein R1 is a C4 to C30 hydrocarbon group; Z is a methylene group, a methine group, or an oxygen atom; X1, X2, X3 is a hydrogen atom, a hydroxyl group, or an acetoxy group; X4 is a hydrogen atom, an acetyl group, or a glyceryl group; each of R2 and R3 a hydrogen atom, a hydroxyl group, a hydroxymethyl group, or an acetoxymethyl group; R4 is a C5 to C60 hydrocarbon group; and R5 is a hydrogen atom or a hydrocarbon group containing 1 to 30 carbon atoms in total;(D) 0.00012 to 10 wt. % of at least one compound selected from the group consisting of a nonionic surfactant having a polyoxyethylene group and an HLB of 10 or higher, an ionic surfactant, and a sphingosine salt;(E) 0.003 to 15 wt. % of at least one compound selected from the group consisting of a sugar alcohol selected from the group consisting of erythritol, threitol, xylitol, and mannitol, a disaccharide, and a trisaccharide; and(F) water.

A photoelectric conversion device is provided and includes a photoelectric conversion layer containing a compound represented by the following formula (1). Formula (1):In the formula, Z1 represents an atomic group for forming a 5- or 6-membered nitrogen-containing heterocyclic ring; Za represents an atomic group for forming a 5- or 6 membered ring; R1 represents a hydrogen atom, an alkyl group, an alkenyl group, an aryl group or a heterocyclic group; L11 to L14 each represents a methine group which may have a substituent or may form a ring with another methine group; p1 represents 0 or 1; n1 represents an integer of 0 to 4 and when n1 is an integer of 2 or more, each L13 or L14 may be the same as or different from every other L13 or L14; M1 represents an ion for neutralizing the electric charge; and m1 represents a number necessary for neutralization of the electric charge; provided that a compound where Z1 is an atomic group forming a thiazoline nucleus or a thiazole nucleus is excluded.

A photoelectric conversion device using a semiconductor fine material such as a semiconductor fine particle sensitized with a dye carried thereon, characterized in that the dye is a methine type dye having a specific partial structure, for example, a methine type dye having a specific carboxyl-substituted hetero ring on one side of a methine group and an aromatic residue substituted with a dialkylamino group or an organic metal complex residue on the other side of the methine group, or a methine type dye having a carboxyl-substituted aromatic ring on one side of a methine group and a heteroaromatic ring having a dialkylamino group or an organic metal complex residue on the other side of the methine group; and a solar cell using the photoelectric conversion element. The photoelectric conversion element exhibits a conversion efficiency comparable or superior to that of a conventionally known photoelectric conversion element sensitized with a methine type dye.

The invention relates to an adhesion promotor for improving adhesion on a substrate surface of an RMA crosslink able composition comprising one or more crosslinkable components comprising a reactive component A with at least two acidic protons C—H in activated methylene or methine groups, a reactive component B with at least two activated unsaturated C═C groups, a catalyst C for catalyzing the RMA crosslinking reaction between components A and B, said adhesion promotor P comprising a moiety comprising one or more functional groups X or precursors thereof readable with component A or component B and a moiety comprising one or more functional groups Y or precursors thereof that adsorb or react with the substrate surface not being an alkoxysilane group. The invention also relates to a RMA crosslinkable composition, also in the form of a kit of parts, to a premix for use as a part in the kit of parts.

A composition and process useful to make flexible polyurethane foams and in particular flexible molded polyurethane foams is disclosed. The usage of dipolar aprotic liquids such as DMSO, DMI, sulfolane, N-methyl-acetoacetamide, N,N-dimethylacetoacetamide as well as glycols containing hydroxyl numbers OH#≦1100 as cell opening aides for 2-cyanoacetamide or other similar molecules containing active methylene or methine groups to make a polyurethane foam is also disclosed. The advantage of using cell opener aids results in a) no foam shrinkage; b) lower use levels of cell opener; c) foam performance reproducibility d) optimum physical properties. In addition, combining the acid blocked amine catalyst together with the cell opener and the cell opener aid results in a less corrosive mixture as well as provides a method that does not require mechanical crushing for cell opening.

Provided is an azole derivative which can be contained as an active ingredient in an agricultural or horticultural chemical agent having an excellent disease control effect. This azole derivative is represented by general formula (I). (In formula (I), R1 represents a C1-C6 alkyl group which may be substituted; R2 represents a functional group containing a carbonyl group, wherein a carbon atom in the carbonyl group is bonded to both a carbon atom substituted by R1 in the cyclopentane ring and any one selected from a hydrogen atom, a hydroxyl group, R3, OR3 and NR3R4; R3 and R4 independently represent a C1-C6 alkyl group, a C2-C6 alkenyl group or a C2-C6 alkynyl group; Y represents a halogen atom, a C1-C4 alkyl group, a C1-C4 haloalkyl group, a C1-C4 alkoxy group, a C1-C4 haloalkoxy group, a phenyl group, a cyano group or a nitro group; m represents 0-5; and A represents a nitrogen atom or a methine group.).

The present invention is to provide a curable coating composition having much less of a volatile organic component, and being excellent in coating film performance such as durability and scratch resistance, and a coating film forming method using the above curable coating composition capable of suppressing generation of sagging and so on. The present invention is a curable coating composition which comprises (a) a component having an active methylene group and / or an active methine group, (b) a component having a methacrylate group and / or an acrylate group, (c) a Michael reaction catalyst and (d) a photo-polymerization initiator. The present invention also provides a coating film forming method which comprises a step (1) of applying a curable coating on a substrate to be coated and a step (2) including a stage of irradiating with ultraviolet ray and a stage of heating, said curable coating comprising the above curable coating composition.

The invention discloses an MOF loaded corrosion inhibitor filler, a self-repairing anticorrosive coating and a preparation method thereof. The filler takes a metal organic framework compound hmt-MOF as a capsule shell and an encapsulated corrosion inhibitor as a capsule core, and an hmt-MOF compound is formed by assembling two organic polydentate ligands including hexamethylenetetramine and terephthalic acid; amino nitrogen atoms in hexamethylenetetramine and carboxyl oxygen atoms in terephthalic acid can react with functional groups in resin, compatibility is good, dispersion is easy, high storage stability is achieved, and the compound can react with a metal substrate to generate -N / O coordination bonds, hydrogen bonds and the like; and the adhesive force and the corrosion resistance ofthe coating and the substrate are enhanced, and a high self-repairing function can be kept for a long time in an acid-base environment. The raw materials are easy to obtain and low in toxicity, the production technological process is simple, preparation is easy, the trend of green and environment-friendly development is met, large-scale industrial production can be achieved, and good application prospects are achieved.

The photosensitive resin composition contains a binder resin (A), a photopolymerizable compound (B), a photopolymerization initiator (C) and a solvent (D), wherein the binder resin (A) comprises a polymer (AA) containing a structural unit (A1) derived from at least one kind of compound selected from a group consisting of unsaturated carboxylic acids and unsaturated carboxylic acid anhydrides, a structural unit (A2) derived from an unsaturated compound having at least one kind of group selected from a group consisting of active methylene groups and active methine groups, and a structural unit (A3) derived from a monomer copolymerizable with the structural unit (A1) and the structural unit (A2), however, (A3) excluding the structural unit (A1) and the structural unit (A2).