The invention relates to an oral pill, and in particular to an oral pill for treating impotence and a preparation method of the oral pill. According to a specific prescription, the finished oral pillproduct is prepared from radix aconiti lateralis preparata, dried ginger, herba cistanche, medical pipefish, hippocampus japonicus, Chinese leek seeds, flos carthami, centipedes, radix morindae officinalis, herba cynomorii, radix polygoni multiflori preparata, silkworm moth, fructus cnidii, fructus alpiniae oxyphyllae, fructus psoraleae, seeds of Chinese dodder, fructus rosae laevigatae, herba epimedii, antler tablets, cassia bark, radix ginseng, spongilla fragilla fragilis leidy, Chinese chives, radix angelicae sinensis, rhizoma polygonati, crocus sativus, colla corii asini, antlet glue, tortoise-shell glue and the like by virtue of such processes as conducting airing, conducting crushing, conducting heating, conducting mixing and the like. The oral pill provided by the invention is low in cost of medicinal raw materials, cheap in process, simple in preparation method and free from toxic and side effects; the syndrome of the impotence in patients can be effectively improved; a remission rate can reach 93.5%; and a non-symptomatic rate is lower than 10%, lower than that of other medicines.