Process for the preparation of NMDA antagonists

Abstract

The invention provides a preparation method for crustacean guanidine containing antimicrobial. The crustacean guanidine containing antimicrobial is compounded after the reaction of crustacean guanidine, chitosan, and surfactant. The preparation method has the procedure that the chitosan is dissolved in the acid containing water, when the temperature rises to 20-60 DEG C under stirring for 0.5-5 hour reaction, then the crustacean guanidine is added for 0.1-2 hours full reaction, and finally the surfactant evenly added and stired; and then the crustacean guanidine containing antimicrobial is made. The crustacean guanidine containing antimicrobial in the textile has the application that the padding process is used to ensure that the textile possesses antibiotic, moisturizing, and skin protecting functions. The application in the agriculture is realized by diluting the crustacean guanidine containing antimicrobial proportionately into operating liquid of definite consistence, then applying the operating liquid to the crops or fruit trees in the means of spray or irrigation. The crustacean guanidine containing antimicrobial can inhibit the microorganisms, can destroy virus, can preserve moisture, and can increase the yield.

Description

Technical field: [0001] The invention relates to an antibacterial agent prepared from natural products guanidine and chitin as raw materials, in particular to a preparation method of an antibacterial agent containing natural polymer chitosan-based guanidine salt (hereinafter referred to as chitoguanidine). technical background: [0002] Guanidine exists in natural products such as proteins, nucleic acids, streptomycin, and various plants such as sugar beets, rice husks, mushrooms, and beans. Humans and animals also contain trace amounts of guanidine, but free guanidine is very unstable and easily absorbed in the air. of carbon dioxide to generate guanidine carbonate, so guanidine usually exists stably in the form of guanidine salt. Guanidine salt is an important component of guanidine compounds, which can be derived into a wide variety of guanidine derivatives, which have good antibacterial properties. [0003] Chitin is the collective name of chitin and chitosan. Chitosan ...

AI Technical Summary

Problems solved by technology

[0004] Although chitosan or guanidine salts can be used as antibacterial agents, chitosan as an antibacterial agent is greatly affected by molecular weight and use environment. Only in suitable molecular weight and acidic environment has obvious antibacterial activity, thus limiting its purpose

In the existing technology, Chinese patent 2003101055431 discloses a "chitin and biofilm finishing agent for textiles and its preparation and application process". Ammonium salts as antimicrobials

Although guanidinium salts have strong antibacterial activity and are less affected by environmental conditions, they usually have a small molecular weight and are easily soluble in water. They are not suitable for applications such as textiles that require a certain durability for antibacterial purposes. As disclosed in Chinese patent 01127470 A formulation of "guanidine polymer laundry disinfectant detergent polyoxyethylene hydroxyguanidine hydrochloride", although it has good antibacterial properties, is a one-time disinfectant treatment agent for clothing, has no durability, and is not suitable as a textile post-treatment agent , In addition, the stability of low-volume guanidine salt is poor, easy to decompose and easy to lose antibacterial activity is also a defect