Rumen bypass becholine microcapsule and preparation technique

A technology of choline chloride and preparation process, which is applied in the directions of microcapsules, capsule transportation, and animal feed molding or processing, can solve the problems such as exposure of compressed and deformed capsule cores, influence product absorption, deformation and rupture, etc., and achieve coating The effect of uniform thickness, increased absorption rate and rounded particles

Inactive Publication Date: 2008-09-24
WUHAN POLYTECHNIC UNIVERSITY
View PDF1 Cites 24 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Considering the problems of choline chloride moisture absorption and vitamin destructiveness, the application uses silicon dioxide as a carrier to solve the problem of moisture absorption; considering the characteristics of the rumen of ruminants, it is hoped that hydrogenated vegetable oil will be used to coat the capsule core to achieve Reduce the absorption of choline chloride in the rumen, but there is a problem of poor solidity when using hydrogenated vegetable oil as a coating. The final product of this application is a cylindrical solid particle with a certain length and diameter, and hydrogenated vegetable oil is used as a coating. Poor solidity, it will be deformed and broken under a little external pressure
Considering the cost and other reasons, the packaging of animal feed additives is usually rela...

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Rumen bypass becholine microcapsule and preparation technique

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] 1. Core material preparation:

[0026] Choline chloride 40kg, starch 10kg, microcrystalline cellulose 5kg, footstone 45kg and 1.5% sodium carboxymethylcellulose aqueous solution 30000ml are mixed in proportion, then granulated by a swing granulator, and then shot blasted by a shot blasting machine. Dry (equipment: FLP type fluidized granulation coating dryer), sieve, the particle size of the sieve is between 16-40 mesh, set aside.

[0027] 2. Preparation of coating solution:

[0028] Add 12g acrylic resin IV to every 100ml95% alcohol solution, stir to make it dissolve to make acrylic resin IV solution; add 3g chitosan to every 100ml4% acetic acid solution, stir to make it dissolve to make chitosan solution; Add 2.5g of ethyl cellulose to the solution, stir to make it dissolve to make ethyl cellulose solution.

[0029] 3. Preparation of microcapsules:

[0030] The above-mentioned granular core material is sent into the coating chamber of the fluidized bed,

[0031] (...

Embodiment 2

[0035] 1. Core material preparation:

[0036] Choline chloride 35kg, starch 5kg, microcrystalline cellulose 10kg, footstone 50kg, 1.5% sodium carboxymethylcellulose aqueous solution 30000ml are mixed in proportion, and all the other are with embodiment 1.

[0037] 2. Preparation of coating solution:

[0038] With embodiment 1.

[0039] 3. Preparation of microcapsules:

[0040] Send the above-mentioned granular core material into the coating chamber of the fluidized bed, and spray acrylic resin IV solution, ethyl cellulose solution, chitosan in sequence in the order of inner layer coating, additional layer coating, and outer layer coating. solution, wherein, the spraying amount of the inner layer coating is 3% of the mass of the core material as the acrylic resin IV after drying as the inner layer coating, and the spraying amount of the additional layer coating is that of ethyl cellulose after drying as the additional layer coating Clothing is 3% of core material quality, an...

Embodiment 3

[0042] 1. Core material preparation:

[0043] Choline chloride 45kg, starch 8kg, microcrystalline cellulose 7kg, footstone 40kg, 1.5% sodium carboxymethylcellulose aqueous solution 30000ml are mixed in proportion, and all the other are with embodiment 1.

[0044] 2. Preparation of coating solution:

[0045] With embodiment 1.

[0046] 3. Preparation of microcapsules:

[0047] Send the above-mentioned granular core material into the coating chamber of the fluidized bed, and spray acrylic resin IV solution, ethyl cellulose solution, chitosan in sequence in the order of inner layer coating, additional layer coating and outer layer coating Solution, wherein, the spraying amount of the inner layer coating is the dried acrylic resin IV as the inner layer coating is 5% of the core material quality, and the spraying amount of the outer layer coating is the dried chitosan as the outer layer coating 3% of the mass of the core material, the spraying amount of the additional layer coat...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a through-rumen choline chloride microcapsule and the preparation technique thereof, and solves the problems that choline chloride has a poor effect through the rumen, ruminants have a low intestinal absorption rate and packing, storage and transportation are not easy. The technical proposal is as follows: choline chloride with a mass percentage of 35 to 40 percent is adopted as the main active ingredient and used as the core material, acrylics IV is used as the internal coating of the core material, chitosan is used as the external coating, and the mass of the internal and external coatings is both 3 to 5 percent of the mass of the core material. The through-rumen choline chloride microcapsule can guarantee that a good moisture resistance is ensured during packing, storage and transportation, deformation and damage fail to occur due to compression, the goal of a slow release can be achieved in the rumen and the intestinal absorption rate of choline chloride is improved.

Description

technical field [0001] The invention relates to a rumen-passed choline chloride microcapsule and a preparation process thereof. Background technique [0002] Choline is one of the B vitamins. In the growth and metabolism of livestock and poultry, choline is the donor of methyl, and is the important bioactive substance in biological tissues—acetylcholine, phospholipid, ceramide, etc. Important component; it can not only improve the utilization rate of amino acids in livestock and poultry, promote fat metabolism, prevent fat accumulation in liver and kidney and tissue deterioration, but also enhance the physical fitness and disease resistance of livestock and poultry, and promote the growth of livestock and poultry . [0003] As an animal feed additive, choline chloride has been widely used in the feeding of various monogastric animals. For example, as a full-price compound feed for chickens in different physiological stages, it can increase the egg production rate of breeder...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K9/50A61K31/14A61K47/32A61K47/36A61K47/38A61P3/02A23K1/16A23K20/10A23K20/163A23K40/10
Inventor 王春维赵胜军侯永清陈东东李建文刘昌杜
Owner WUHAN POLYTECHNIC UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap