Biomedical material with silver-ion-bearing hydroxyapatite coating and preparation method thereof
A technology of biomedical materials and hydroxyapatite, which is applied in the field of surface modification of biomedical materials, can solve the problems of unfavorable release of antibacterial materials and uneven distribution of antibacterial materials, so as to achieve good antibacterial effect, reduce costs, and achieve good results. The effect of uniformity
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
preparation example Construction
[0039] (1) Preparation of hydroxyapatite suspension
[0040] According to the calcium-phosphorus molar ratio of 1.67, prepare an aqueous solution of calcium nitrate with a molar concentration of 0.5-2.5 mol / L and an aqueous solution of diammonium hydrogen phosphate with a molar concentration of 0.5-3 mol / L; The aqueous solution is added dropwise to the calcium nitrate aqueous solution at a rate of 5-15ml / min for reaction, and then ammonia water with a percentage concentration of 10%-30% is added dropwise to the reaction solution at a rate of 1-10ml / min, and the pH of the reaction solution is controlled to be 9-12, keep the reaction temperature at 30-90°C, after the complete reaction, let stand for 5-15 minutes, and then age for 24-48 hours to prepare the hydroxyapatite suspension for use;
[0041] (2) Loading of antibacterial materials
[0042] A certain amount of antibacterial material is added to the hydroxyapatite suspension under constant stirring, and the mass ratio of t...
Embodiment 1
[0047] Example 1 Preparation of Hydroxyapatite Bioactive Coating by Powder Plasma Spraying
[0048] In this example, hydroxyapatite powder is used as the raw material for spraying. Use atmospheric plasma spraying equipment (Sulzer Metco MNspray system and AR2000 robot arm) to spray a layer of HA coating on the surface of the substrate, the coating thickness is 100 microns, the spraying power is 24 kW, the spraying distance is 100 mm, and the hydroxyapatite powder is directly injected In the central area of the plasma flame, a coating is finally formed on the titanium alloy substrate. The surface morphology of the coating is observed with a scanning electron microscope. The scanning electron microscope photo is shown in figure 1 (a). For the antibacterial properties of its coating, see figure 2 .
Embodiment 2
[0049] Embodiment two liquid phase ion spraying hydroxyapatite bioactive coating
[0050] First, prepare the hydroxyapatite suspension as the raw material for spraying. According to the molar ratio of calcium to phosphorus of 1.67, configure an aqueous solution of calcium nitrate with a molar concentration of 1.6mol / L and an aqueous solution of diammonium hydrogen phosphate with a molar concentration of 2.5mol / L; under continuous and sufficient stirring , the above-mentioned configured diammonium hydrogen phosphate aqueous solution and ammonia water with a percentage concentration of 30% are added dropwise to the configured calcium nitrate aqueous solution at a rate of 5ml / min for reaction, and the pH value of the reaction solution is kept at 10. The temperature is 40°C. After the reaction is complete, it is left to stand for 5 minutes, and finally aged for 24 hours to prepare a suspension of hydroxyapatite as a raw material for spraying.
[0051] In this example, the B702 ele...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com