Cataplasm of veterinary traditional Chinese medicine clearing away heat and toxic materials and preparation method of cataplasm
A technology for clearing away heat and detoxification and poultice, which can be used in antipyretics, pharmaceutical formulations, non-central analgesics, etc., and can solve the problems that human-type poultice cannot be easily transplanted, and drugs are difficult to penetrate through the skin, etc.
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Embodiment 1
[0022] Take 1 kg of honeysuckle extract, 1.2 kg of forsythia extract, 1 kg of dandelion extract, 1 g of toad venom, 200 g of eucalyptus oil, 90 g of borneol, 110 g of menthol, 90 g of camphor, NP-700 sodium polyacrylate 550g, Carbomer 940 550g, Povidone 180g, Polyvinyl Alcohol 220g, Sodium Carboxymethylcellulose 140g, Glycerin 6kg, Aluminum Glycinate 10g, EDTA 50g, Azone 100g, 2 % citric acid 20 grams. Then prepare veterinary heat-clearing and detoxifying traditional Chinese medicine cataplasm according to the following steps: (1) Evenly disperse Carbomer 940 in 4400ml of distilled water, let it stand for 10 hours, stir evenly until it swells completely, and adjust the pH with 20% sodium hydroxide To 7.2, making it into a slightly white transparent jelly;
[0023] (2) Disperse NP-700 sodium polyacrylate, sodium carboxymethyl cellulose and aluminum glycinate in glycerin, stir, let it stand for 4 hours, add eucalyptus oil, stir well, and it becomes a viscous liquid;
[0024] (...
Embodiment 2
[0036] Take 1.2 kg of honeysuckle extract, 1 kg of forsythia extract, 1.2 kg of dandelion extract, 1.5 g of toad venom, 100 g of eucalyptus oil, 110 g of borneol, 90 g of menthol, 110 g of camphor, NP-700 sodium polyacrylate 450g, carbomer 940 650g, povidone 220g, polyvinyl alcohol 180g, sodium carboxymethylcellulose 160g, glycerin 5kg, aluminum glycinate 30g, EDTA 30g, azone 140g, 2 % citric acid 5 grams. Then follow the steps below to prepare veterinary heat-clearing and detoxifying traditional Chinese medicine cataplasms: (1) Evenly disperse Carbomer 940 in 5200ml of distilled water, let it stand for 14 hours, stir until it is completely swollen, and adjust the pH with 20% sodium hydroxide to 6.8, making it into a slightly white transparent jelly;
[0037] (2) Disperse sodium polyacrylate, sodium carboxymethyl cellulose and aluminum glycinate in glycerin, stir, let stand for 6 hours, add eucalyptus oil, stir well, it becomes viscous liquid;
[0038] (3) Add polyvinyl alco...
Embodiment 3
[0050] Take 1.1 kg of honeysuckle extract, 1.1 kg of forsythia extract, 1.1 kg of dandelion extract, 1.2 g of toad venom, 110 g of eucalyptus oil, 100 g of borneol, 100 g of menthol, 100 g of camphor, NP-700 sodium polyacrylate 500g, carbomer 940 600g, povidone 200g, polyvinyl alcohol 200g, sodium carboxymethylcellulose 150g, glycerin 5.5kg, aluminum glycinate 20g, EDTA 40g, azone 120g, 2 % citric acid 15 grams. The preparation method is the same as in Example 1.
[0051] Transdermal Effect Test of Veterinary Heat-clearing and Toxic Medicine Catapult Prepared in Implementation 3
[0052] Test method: Using ZTY type transdermal diffusion instrument, using fresh calfskin as the test material, and ethanol saline as the receiving solution, the chlorogenic acid and caffeic acid in the veterinary heat-clearing and detoxifying cataplasm were detected by LUMTECH high-performance liquid chromatography The amount permeated through calf skin at six time points (2h, 4h, 6h, 8h, 10...
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