Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Cataplasm of veterinary traditional Chinese medicine clearing away heat and toxic materials and preparation method of cataplasm

A technology for clearing away heat and detoxification and poultice, which can be used in antipyretics, pharmaceutical formulations, non-central analgesics, etc., and can solve the problems that human-type poultice cannot be easily transplanted, and drugs are difficult to penetrate through the skin, etc.

Inactive Publication Date: 2013-05-01
SHANXI AGRI UNIV
View PDF8 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the skin structure of animals and humans is quite different, some animals have a thicker dermis, and it is difficult for drugs to penetrate the skin. Catapults for the development of veterinary drugs with specific characteristics

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Cataplasm of veterinary traditional Chinese medicine clearing away heat and toxic materials and preparation method of cataplasm
  • Cataplasm of veterinary traditional Chinese medicine clearing away heat and toxic materials and preparation method of cataplasm

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Take 1 kg of honeysuckle extract, 1.2 kg of forsythia extract, 1 kg of dandelion extract, 1 g of toad venom, 200 g of eucalyptus oil, 90 g of borneol, 110 g of menthol, 90 g of camphor, NP-700 sodium polyacrylate 550g, Carbomer 940 550g, Povidone 180g, Polyvinyl Alcohol 220g, Sodium Carboxymethylcellulose 140g, Glycerin 6kg, Aluminum Glycinate 10g, EDTA 50g, Azone 100g, 2 % citric acid 20 grams. Then prepare veterinary heat-clearing and detoxifying traditional Chinese medicine cataplasm according to the following steps: (1) Evenly disperse Carbomer 940 in 4400ml of distilled water, let it stand for 10 hours, stir evenly until it swells completely, and adjust the pH with 20% sodium hydroxide To 7.2, making it into a slightly white transparent jelly;

[0023] (2) Disperse NP-700 sodium polyacrylate, sodium carboxymethyl cellulose and aluminum glycinate in glycerin, stir, let it stand for 4 hours, add eucalyptus oil, stir well, and it becomes a viscous liquid;

[0024] (...

Embodiment 2

[0036] Take 1.2 kg of honeysuckle extract, 1 kg of forsythia extract, 1.2 kg of dandelion extract, 1.5 g of toad venom, 100 g of eucalyptus oil, 110 g of borneol, 90 g of menthol, 110 g of camphor, NP-700 sodium polyacrylate 450g, carbomer 940 650g, povidone 220g, polyvinyl alcohol 180g, sodium carboxymethylcellulose 160g, glycerin 5kg, aluminum glycinate 30g, EDTA 30g, azone 140g, 2 % citric acid 5 grams. Then follow the steps below to prepare veterinary heat-clearing and detoxifying traditional Chinese medicine cataplasms: (1) Evenly disperse Carbomer 940 in 5200ml of distilled water, let it stand for 14 hours, stir until it is completely swollen, and adjust the pH with 20% sodium hydroxide to 6.8, making it into a slightly white transparent jelly;

[0037] (2) Disperse sodium polyacrylate, sodium carboxymethyl cellulose and aluminum glycinate in glycerin, stir, let stand for 6 hours, add eucalyptus oil, stir well, it becomes viscous liquid;

[0038] (3) Add polyvinyl alco...

Embodiment 3

[0050] Take 1.1 kg of honeysuckle extract, 1.1 kg of forsythia extract, 1.1 kg of dandelion extract, 1.2 g of toad venom, 110 g of eucalyptus oil, 100 g of borneol, 100 g of menthol, 100 g of camphor, NP-700 sodium polyacrylate 500g, carbomer 940 600g, povidone 200g, polyvinyl alcohol 200g, sodium carboxymethylcellulose 150g, glycerin 5.5kg, aluminum glycinate 20g, EDTA 40g, azone 120g, 2 % citric acid 15 grams. The preparation method is the same as in Example 1.

[0051] Transdermal Effect Test of Veterinary Heat-clearing and Toxic Medicine Catapult Prepared in Implementation 3

[0052] Test method: Using ZTY type transdermal diffusion instrument, using fresh calfskin as the test material, and ethanol saline as the receiving solution, the chlorogenic acid and caffeic acid in the veterinary heat-clearing and detoxifying cataplasm were detected by LUMTECH high-performance liquid chromatography The amount permeated through calf skin at six time points (2h, 4h, 6h, 8h, 10...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses cataplasm of a veterinary traditional Chinese medicine clearing away heat and toxic materials and a preparation method of the cataplasm. The cataplasm comprises raw materials in parts by mass as follows: 10-12 parts of a honeysuckle extract, 10-12 parts of a fructus forsythiae extract, 10-12 parts of a dandelion extract, 0.01-0.015 part of venenum bufonis, 1-2 parts of eucalyptus oil, 0.9-1.1 parts of borneol, 0.9-1.1 parts of menthol, 0.9-1.1 parts of camphor, 4.5-5.5 parts of NP-700 type sodium polyacrylate, 5.5-6.5 parts of carbomer 940, 1.8-2.2 parts of povidone, 1.8-2.2 parts of polyvinyl alcohol, 1.4-1.6 parts of sodium carboxymethylcellulose, 50-60 parts of glycerol, 0.1-0.3 part of aluminum glycinate, 0.3-0.5 part of EDTA (ethylene diamine tetraacetic acid), 1.0-1.4 parts of azone and 0.05-0.2 part of 2% of citric acid. The preparation method comprises the steps that the group of the components is prepared into a paste according to a certain method and certain steps, the paste is applied onto a non-woven fabric, the fabric is covered by a separate paper protective film, and then the film is sealed by a plastic bag, so that a finished product is obtained. Experiments show that the cataplasm has the functions of suppressing pain and resisting swelling, and can be used for diseases which are not ulcerated in a preliminary stage, such as sores, ulcers, malignant boils, poisons and the like; and the functional components of the cataplasm can penetrate through the skin of a calf, the matrix is a non-toxic and innocuous high polymer material, and no environmental pollution exists during processing and usage.

Description

technical field [0001] The invention relates to the technical field of veterinary drug production, in particular to a veterinary traditional Chinese medicine cataplasm for clearing heat, detoxifying, reducing swelling and relieving pain and a preparation method thereof. Background technique [0002] Although the traditional Chinese medicine black plaster has a good curative effect on many traumatic diseases such as sores, bruises, rheumatic pains, and internal diseases such as cough and asthma, waist and knee pain, food accumulation, mastitis, and menstrual pain, but its A large amount of lead red is required in the preparation and production process, which not only damages the pharmaceutical workers but also pollutes the environment, and its quality control is difficult to standardize, so it has lost its original status. [0003] The cataplasm is an external patch made of non-toxic and harmless polymer material as the matrix. It can be peeled and pasted repeatedly, and it i...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/634A61K9/70A61P29/00A61P17/02A61K35/56A61K31/125A61K31/045A61K35/65
Inventor 王文魁张美萍孙荣荣程佳李雪莲周利青郭娜任鸿春曹文斌刘睿芬刘耀伟白峰齐永华
Owner SHANXI AGRI UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products