Medical implant material surface modifying method

A technology for surface modification and implantation of materials, applied in abrasives, medical science, prostheses, etc., can solve the problems of reducing the corrosion resistance of the implant surface, irregular hole shape, and long acid etching treatment time, so as to shorten the healing time Time, good stretch, good for bonding effect

Inactive Publication Date: 2013-06-12
大连理工(营口)新材料工程中心有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The invention patents with the publication numbers of CN 101904774A and CN 102113918A both adopt the treatment method of sandblasting and acid etching. The holes formed on the titanium surface are limited to microns and the shape of the holes is irregular. The subsequent acid etching treatment takes a long time, which is easy to cause hydrogen embrittlement. And reduce the corrosion resistance of the implant surface

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] (1) Place the TC4 titanium alloy implant in a mixture of 20g / L sodium silicate, 3g / L emulsifier OP-10, and water (the balance) for ultrasonic cleaning for 30min at 70°C and dry;

[0016] (2) Place in a mixed solution of 1% ammonium fluoride, 1% hydrofluoric acid, 10% nitric acid and water (remainder), process for 45s, temperature 60°C, and dry;

[0017] (3) Sandblasting the surface, using titanium dioxide as the sandblasting abrasive, with a purity of ≥98%, a particle size of 0.1~0.5mm, a spray distance of 20mm, and a sandblasting time of 20s. The surface forms a rough surface with ups and downs, and the pit size is 10~50μm , then ultrasonically cleaned in ethanol, and dried;

[0018] (4) Use the Nadezhda-2 high-current pulsed electron beam system to process the sample, so that a large number of micron and submicron holes are formed on the surface on the basis of the original depressions, with a size of 0.5-5 μm. Main parameter range: accelerating voltage 25keV, pulse ...

Embodiment 2

[0021] (1) Put the Ti-6Al-7Nb titanium alloy implant in a mixture of 30g / L sodium silicate, 7g / L emulsifier OP-10 and water (remainder) for ultrasonic cleaning for 15min at 60°C and bake Dry;

[0022] (2) Place in a mixed solution of 2% ammonium fluoride, 2% hydrofluoric acid, 10% nitric acid and water (remainder), process for 45 seconds, and dry at 60°C;

[0023] (3) Surface sandblasting, the sandblasting abrasive is made of titanium dioxide, the purity is ≥98%, the particle size is 0.1~0.5mm, the spray distance is 40mm, the sandblasting time is 30s, the surface forms a rough surface with ups and downs, the size of the pit

[0024] 10~50μm, then ultrasonically cleaned in ethanol and dried;

[0025] (4) Use the Nadezhda-2 high-current pulsed electron beam system to process the sample, so that a large number of micron and submicron holes are formed on the surface on the basis of the original depressions, with a size of 0.5-5 μm. Main parameter range: accelerating voltage 27k...

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Abstract

The invention discloses a medical implant material surface modifying method which comprises the following steps of: putting a titanium alloy implantation body into a mixture liquid, washing for 15-30 minutes in an ultrasonic mode, and drying; putting into the mixture liquid and treating for 30-45 seconds at 50-60 DEG C, and drying; carrying out sand spraying treatment to form a high-low rough surface on the surface, subsequently putting ethanol to carry out ultrasonic washing, and drying; treating a sample by using a strong current pulse electronic beam system so as to generate micron and submicron grade pores on the surface on the basis of the original recesses; putting into the mixture liquid and treating for 2-4 minutes at 110-130 DEG C, wherein pores less than 0.5 micrometer are generated on the inner walls and the pore ridges of the original pores; taking out the sample, putting into deionized water to be subjected to ultrasonic washing, and drying. By preparing the surface with micron and nano multi-grade micropore composite structures in such mode, the ambient tissue reaction activity can be irritated, and osteoblast cells are good in adhesion and extension.

Description

technical field [0001] The invention relates to the surface modification technology of biomedical metal materials, in particular to a method for modifying the surface of titanium alloy, a human body hard tissue substitute material, by using technologies such as specific pretreatment, pulsed electron beam treatment, and corrosion. Background technique [0002] Currently, substitute materials for hard tissues such as artificial joints, artificial bones, and artificial teeth are widely used in the medical field. Titanium and titanium alloys as alternative materials have light specific gravity, elastic modulus and tensile strength close to that of bone, and superior corrosion resistance and biocompatibility. The ideal way of combining human hard tissue replacement materials with bone tissue is bone bonding in the form of chemical bonds. This combination can not only increase the bonding strength between the implanted prosthesis and bone, but also shorten the healing time of the ...

Claims

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Application Information

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IPC IPC(8): A61L27/06A61L27/56B24C1/06B24C11/00
Inventor 周文龙焦岩付雪松昌锋
Owner 大连理工(营口)新材料工程中心有限公司
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