Preparation method of microencapsulation diolame sodium butyrate

Abstract

The invention relates to a preparation method of an animal feed additive microencapsulation diolame sodium butyrate. The method comprises the following steps of: mixing hydroxypropyl methyl cellulose, chitosan and silica, boiling at high temperature of 230DEG C in a fluidized bed; spraying sodium butyrate aqueous solution on a mixture of three materials; drying at a high temperature, solidifying at a low temperature, solidifying and molding sodium butyrate particles; dissolving a coated material Brazil palm wax, palm oil and polyethylene glycol into an organic solvent, carrying out bottom-spraying and coating in a fluidized bed to obtain the evenly-coated sodium butyrate particles of which the mass percent of the sodium butyrate is 30-70%. The microencapsulation process is carried out on feed grade sodium butyrate power to avoid the loss of sodium butyrate in poultry crop and pig stomach, so as to reach the rear section of small intestine and cover the whole intestinal tract, meanwhile, overcomes foul smell, prevents air slaking, and protects sodium butyrate from losing in the process of feed processing.

Description

Technical field [0001] The patent of the present invention relates to a preparation method of microencapsulated coated sodium butyrate for animal feed additives. Background technique [0002] Sodium butyrate, also known as sodium n-butyrate, is converted into butyric acid after being eaten by animals. It is the same short-chain fatty acid (SCFA) as acetic acid and propionic acid. Butyric acid plays a major role in short-chain fatty acids. Unlike short-chain volatile fatty acids such as acetic acid or propionic acid, butyric acid is hydrolipidic and more lipophilic. It is relatively stable at pH 4-6 and is not easily decomposed. The molecular formula of sodium butyrate is C 4 H 7 O 2 Na, with a relative molecular mass of 110.09, is white to off-white, is a hygroscopic powder, like a fluff, has a special cheese-like smell, is easily soluble in water, and the pH value of the aqueous solution is alkaline. [0003] Sodium butyrate used as a feed additive in breeding can promote the gro...

AI Technical Summary

Problems solved by technology

[0004] Ordinary sodium butyrate is highly irritating to the esophagus and stomach, and is easy to absorb moisture, which affects the processing quality of the feed, and has a strange smell, which affects the customer's recognition of the quality of the feed

In addition, ordinary sodium butyrate is mostly absorbed in the crop or stomach, and only a small part reaches the intestinal tract. At the same time, the gastric acid environment also has a greater impact on sodium butyrate, so ordinary sodium butyrate cannot satisfy the needs of various intestinal components. Nutrient requirements for sodium butyrate

In the process of feed processing, factors such as moisture content in feed, carrier type, pelleting temperature and other factors also have a great influence on the stability of ordinary sodium butyrate, which may cause greater losses

[0005] At present, the technical means used in the relevant research on the protection of butyric acid mainly include coating technology and chemical esterification technology. The coating technology mainly uses different types of coating materials to coat sodium butyrate to protect butyric acid as much as possible. Salt is not absorbed in the stomach, but the current technology is immature, and its loss in gastric juice is relatively large, and the dissolution effect in intestinal juice is not ideal. It mainly provides nutrition for the small intestine, and only a small amount can reach the large intestine; and the market High sales price, difficult to promote

Chemical esterification technology is still in its infancy and difficult to popularize and apply

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