Preparation method and application of edible and medicinal fungus nanofilm

Abstract

The invention discloses a preparation method of an edible and medicinal fungus nanofilm. The preparation method comprises steps of slant culture, seed culture, amplification culture, and producing of a nano material. The nanofilm can be directly synthesized by microorganisms, has uniform structure, controllable appearance, and short synthesis cycle, and is applicable to expanded production. The fungus nanofilm comprises beta-glucan and chitin, wherein beta-glucan can comprehensively activate the immune system of human bodies, activate macrophage and neutrophilic granulocyte, resist diseases caused by microorganisms, and activate the nonspecific immunity of a host for curing tumours, infectious diseases and wounds, and chitin also has good antibacterial effects. The edible and medicinal fungus nanofilm has good hygroscopicity and breathability, can resist bacteria, diminish inflammation and promote wound healing, can be used as artificial skin, is degradable naturally, and has an obvious three-dimensional space net structure, so that the fungus nanofilm can be combined with drugs to be used as sustained-release materials to be applicable to fields such as health care and the like.

Description

technical field [0001] The invention belongs to the intersecting technical fields of microbial technology and nanotechnology, and in particular relates to a preparation method of edible and medicinal fungal nanofilms such as ganoderma lucidum and a method for applying it to medical care fields such as artificial skin. Background technique [0002] Bacterial cellulose is a type of nanocellulose produced by Acetobacter xylinum, which is composed of β-D-glucose connected by β-1,4-glucosidic bonds. As a new type of biological nanomaterial, it has good biological properties. Compatibility and biodegradability, the use of bacterial cellulose to produce artificial skin, scaffold materials and antibacterial materials are current research hotspots, but due to the shortcomings of bacterial cellulose synthesis, such as difficulty in orientation, long production cycle, and difficulty in large-scale application, Therefore, there is a need to obtain new microbial nanomaterials to meet the...

AI Technical Summary

Problems solved by technology

[0005] At present, there have been studies on the immobilized film obtained from the fruiting body of Ganoderma lucidum after alkaline digestion and decolorization for artificial skin, or the slow-release material prepared by mixing the digestive juice with microcrystalline cellulose. In the above process, strong alkali needs to be added, which may cause Affect the biological safety of the product; and due to the long growth cycle and high cost of the fruiting bodies of Ganoderma lucidum, artificial skin and slow-release materials cannot be mass-produced