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Qingzhuo Yishen Capsules

A technology of clearing turbidity and nourishing the kidney and capsules, applied in capsule delivery, plant raw materials, urinary system diseases, etc., can solve problems such as cataract, femoral head necrosis, adrenal insufficiency, water and sodium retention hypertension, etc., to improve kidney Effects of blood flow, delay of kidney damage, and low recurrence rate

Active Publication Date: 2016-01-20
XIANGYU PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If you take adrenal corticosteroids for a long time, it has been proven that there will be a lot of adverse reactions: fat metabolism disorder, edema, abnormal body fat distribution, etc.; protein decomposition, increased metabolism, negative balance of nitrogen, and muscle atrophy , muscle weakness, difficult wound healing, etc.; the disorder of sugar metabolism leads to hyperglycemia and diabetes; Those who are prone to peptic ulcer and severe gastric perforation can lead to gastric perforation; pleasure and excitement in the nervous system can lead to insomnia, and severe psychotic seizures can occur; due to the formation of inhibitory antibodies, infection and tuberculosis are more likely to occur and spread; a large number, Long-term medication can also cause cataract and aseptic necrosis of the femoral head; such as sudden drug withdrawal or surgical infection, it can cause adrenal insufficiency, leading to nausea, vomiting, abdominal pain, shock, etc.
Therefore, the use of standardized hormone therapy in Western medicine has poor effects, many side effects, and a high recurrence rate.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A Qingzhuo Yishen capsule for treating nephrotic syndrome, which is prepared from the following raw materials: 100g of Cordyceps sinensis, 1400g of Astragalus membranaceus, 280g of Salvia miltiorrhiza, 280g of safflower, 280g of Suanzaoren, 500g of dodder, and 100g of rhubarb.

[0034] The preparation method of the Qingzhuo Yishen Capsules is as follows: taking the crude drug by weight for subsequent use

[0035] (1) Grind Cordyceps sinensis into fine powder;

[0036] (2) Take astragalus, salvia miltiorrhiza, safflower, jujube seed, add water and decoct twice, add 10 times the amount of water for the first time, decoct for 1.5 hours, and obtain the filtrate and medicinal residue after filtration;

[0037] (3) Add rhubarb to the dregs obtained in step (2), add 8 times the amount of water, decoct for 1 hour, and filter to obtain the filtrate

[0038] (4) Combine the filtrates of step (2) and step (3), concentrate into a clear paste with a relative density of 1.14-1.16 (8...

Embodiment 2

[0043] A Qingzhuo Yishen Capsule, which is prepared from the following raw materials:

[0044] Astragalus 1400g, Salvia miltiorrhiza 280g, safflower 280g, jujube seed 280g, dodder seed 500g,

[0045] Rhubarb 100g, Seaweed 100g, Epimedium 80g, Curcuma 80g, Aconite 70g,

[0046] Gorgon 70g, Poria 70g, Atractylodes 60g, Melon seeds 60g, Pueraria 60g,

[0047] 50g white lentils, 50g purslane, 50g citrus aurantium, 40g mulberry, 40g lingxiaohua,

[0048] Baibu 30g, pinellia 30g, medlar 30g.

[0049] The preparation method of the Qingzhuo Yishen Capsules is as follows: taking the crude drug by weight for subsequent use

[0050] (1) Take aconite, Gorgon fruit, Poria cocos, Atractylodes atractylodes, Citrus aurantium, mulberry, Ling Xiaohua, Baibu, Pinellia and grind them into fine powder;

[0051] (2) Take astragalus, salvia miltiorrhiza, safflower, jujube seed, add water to decoct, add 10 times the amount of water, decoct for 1.5 hours, filter to obtain filtrate and medicinal resi...

Embodiment 3

[0057] clinical information

[0058] The observed cases were all hospitalized patients, a total of 136 patients, including 70 males and 66 females, aged 21-70 years, with an average age of 32.7 years; the course of disease was 3 months to 2 years, 136 patients were randomly divided into 3 groups, There were 46 people in the control group, 45 people in the Example 1 group, and 45 people in the Example 2 group.

[0059] Inclusion criteria:

[0060] (1) massive proteinuria, urine protein quantitative ≥ 3.5g / d; (2) hypoalbuminemia, plasma albumin ≤ 30g / L; (3) edema; (4) hyperlipidemia. Among them, (1) and (2) are necessary conditions for diagnosis. Nephrotic syndrome caused by systemic and congenital genetic diseases, elevated blood urea nitrogen (BUN), creatinine (Scr) or decreased endogenous creatinine clearance (Ccr) before treatment were excluded.

[0061] treatment method:

[0062] Control group: Oral prednisone at a dose of 1 mg / (kg·d) in the morning, with the maximum da...

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Abstract

The invention relates to a capsule for clearing away turbid and tonifying kidneys. The capsule is prepared from the following raw materials by weight: 100g of cordyceps sinensis, 1400g of astragalus membranaceus, 280g of root of red-rooted salvia, 280g of flowers carthami, 280g of spina date seeds, 500g of semen cuscutae and 100g of rheum officinale. The applied capsule for clearing away turbid and tonifying the kidneys is used for treating both deficiency and excess and treating both symptoms and root causes, is accurate in curative effect, rigorous in formula, and simple and convenient to prepare, and has a broad application prospect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a Qingzhuo Yishen capsule which uses Chinese herbal medicines as raw materials for treating nephrotic syndrome. Background technique [0002] Kidney disease has become one of the major diseases endangering public health. Moreover, due to non-standard treatment, drug abuse and unhealthy lifestyle, the incidence of kidney disease in my country has also increased year after year. Nephrotic syndrome (NS), referred to as nephrotic syndrome, refers to a group of glomerular diseases caused by various etiologies, mainly including increased glomerular basement membrane permeability and decreased glomerular filtration rate. sign. Nephrotic syndrome is not an independent disease, but a group of syndromes in glomerular diseases. Its typical symptoms are massive proteinuria, hypoalbuminemia, high edema, and hyperlipidemia. It can be caused by many kinds o...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/725A61K36/9066A61K9/48A61P13/12
Inventor 林凡友
Owner XIANGYU PHARMA