Cellulose 6-aminocaproate and its synthesis method and application

A technology of aminocaproic acid and cellulose ester, applied in coating and other directions, can solve the problems of high viscosity of solution, inconvenient experimental operation, unsatisfactory effect of inhibiting non-specific adsorption of proteins, etc., and achieves low cost, wide source, inhibition of non-specific The effect of adsorption
CN103923217BInactive Publication Date: 2016-08-17SHAANXI NORMAL UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHAANXI NORMAL UNIV
Publication Date
2016-08-17
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses 6-amino caproic acid cellulose ester as well as a synthetic method and application thereof. According to the 6-amino caproic acid cellulose ester, some hydroxyls of cellulose are substituted by a group as shown in the specification, and the total average degree of substitution of the group on each glucose unit ring is 0.6-1.2. The 6-amino caproic acid cellulose ester is synthesized from raw materials derived from a wealth of sources, the reaction conditions are gentle, the cost is low, the synthesized 6-amino caproic acid cellulose ester can be used as a surface modifying reagent for a polydimethylsiloxane micro-fluidic chip and physically adsorbed on the surface of a passage of the polydimethylsiloxane micro-fluidic chip to form a monomolecular film with positive charges, so that the surface hydrophilicity of the passage of the polydimethylsiloxane micro-fluidic chip can be improved, and nonspecific adsorption of protein on the surface of the passage of the micro-fluidic chip can be effectively inhibited, so high-efficiency reappearance and separation of analyte are realized.
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Description

technical field

[0001] The invention belongs to the technical field of microfluidic chip surface modification reagents, and specifically relates to cellulose 6-aminocaproate and its synthesis method and application. Background technique

[0002] Cellulose esters are derivatives prepared from cellulose as an intermediate, and cellulose is a compound composed of hundreds or thousands of anhydroglucose units. This combination of anhydroglucose units is called poly-β-glucoside chains, and cellulose esters can be prepared by esterifying cellulose with specific carboxylic acids or anhydrides. The cellulose esters that are actually commercially used include: cellulose acetate, cellulose nitrate, cellulose acetate butyrate and cellulose sulfonate. These cellulose esters are widely used in industrial production. However, in today's most promising microfluidic analysis systems, the application of cellulose esters is greatly limited.

[0003] The dynamic physical coating method is cu...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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