Granules of iron-based montmorillonite and preparation method thereof
A technology of iron-based montmorillonite and granules, which is applied in the field of pharmaceutical preparations of iron-based montmorillonite, and achieves the effect of good market prospect and improvement of anti-oxidative stability
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Embodiment 1
[0035] The preparation formula of the present invention is made up of following components:
[0036]
[0037] Make 1000 bags, each bag is 10g, each bag contains 0.225g of ferrous ion
[0038] The weight percent of iron ion in the described iron-based montmorillonite powder is 5%
[0039] (1) soft material: take 295g pregelatinized starch, add 4500ml70% ethanol and stir to mix evenly, be mixed with pregelatinized starch slurry; then take 4500g iron-based montmorillonite powder, add 5000g fructose, 200g aspartame And 3.0g of vitamin C, 1.0g of xylitol, and 1.0g of glucosinolate were mixed evenly, and then pregelatinized starch slurry was added and stirred evenly to make a soft material;
[0040] (2) Granulation: adopt extrusion granulation method, the soft material prepared in step (1) is crossed 20 mesh sieves with mechanical extrusion method to obtain wet granules;
[0041] (3) Drying: place the wet granules prepared in step (2) in a vacuum oven at 50°C to dry;
[0042] ...
Embodiment 2
[0044] The preparation formula of the present invention is made up of following components:
[0045]
[0046] Made into 1000 bags, each bag is 10g, each bag contains 0.315g of ferrous ion
[0047] The weight percent of iron ion in the described iron-based montmorillonite powder is 7%
[0048] (1) soft material: take 295g pregelatinized starch, add 4500ml70% ethanol and stir to mix evenly, be mixed with pregelatinized starch slurry; then take 4500g iron-based montmorillonite powder, add 5000g fructose, 200g aspartame And 3.0g of vitamin C, 1.0g of xylitol, and 1.0g of glucosinolate were mixed evenly, and then pregelatinized starch slurry was added and stirred evenly to make a soft material;
[0049](2) granulation: adopt extrusion granulation method, the soft material prepared in step (1) is crossed 24 mesh sieves with mechanical extrusion method and makes wet granule;
[0050] (3) Drying: place the wet granules prepared in step (2) in a vacuum oven at 55°C;
[0051] (4) ...
Embodiment 3
[0053] The preparation formula of the present invention is made up of following components:
[0054]
[0055] Make 1000 bags, each bag is 10g, each bag contains 0.270g of ferrous ion
[0056] The weight percent of iron ion in the described iron-based montmorillonite powder is 6%
[0057] (1) soft material: take 295g pregelatinized starch, add 4500ml70% ethanol and stir to mix evenly, be mixed with pregelatinized starch slurry; then take 4500g iron-based montmorillonite powder, add 5000g fructose, 200g aspartame And 3.0g of vitamin C, 1.0g of xylitol, and 1.0g of glucosinolate were mixed evenly, and then pregelatinized starch slurry was added and stirred evenly to make a soft material;
[0058] (2) Granulation: adopt extrusion granulation method, the soft material prepared in step (1) is crossed 20 mesh sieves with mechanical extrusion method to obtain wet granules;
[0059] (3) Drying: place the wet granules prepared in step (2) in a vacuum oven at 60°C to dry;
[0060] ...
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