High-strength degradable bone fracture binding band and preparation method thereof

Abstract

The invention discloses a high-strength degradable bone fracture binding band and a preparation method of the high-strength degradable bone fracture binding band and belongs to the technical field of medical instruments. The bone fracture binding band is formed by combined preparation of a high-strength orientation fiber band and a randomly arranged fiber film or a random orientation thin film. The degree of crystallinity is increased through a nucleating agent, and the orientation technology is adopted to obtain the high-strength orientation fiber band; the bone fracture binding band is prepared under the condition that the linear speed of a disc-shaped yarn take-up device is greater than or equal to 500 m / min by the adoption of the solution electrospinning technology; the mass percent of a spinning solution is that a degradable polymer accounts for 5-12%, the nucleating agent accounts for 0.5-2%, and a solvent accounts for 86-95%. The orientation fiber band is arranged in a single orientation or double orientations, the random fiber film is sprayed on the surface of the orientation fiber band, or the random orientation thin film is stacked on the orientation fiber band, and then the bone fracture binding band is prepared by means of ultrasonic welding. The tensile strength and tensile modulus of the prepared bone fracture binding band are improved substantially compared with those of a randomly arranged electrostatic spinning film, and the bone fracture binding band has good application prospect with respect to repair and fixation of clinical bone fractures.

Description

technical field [0001] The invention belongs to the technical field of medical devices, in particular to a high-strength and degradable fracture binding belt and a preparation method thereof. Background technique [0002] A fracture is a complete or partial break in the continuity of the bone structure. There are three main reasons for fractures: one is direct violence. Violence directly acts on a certain part of the bone to cause a fracture in that part, causing fractures in the injured part, often accompanied by soft tissue damage to varying degrees. For example, when a wheel hits the calf, fractures of the tibial and fibula shafts occur at the impact site; the second is indirect violence. During indirect violence, fractures occur in the distance through longitudinal conduction, leverage or torsion. Gravity causes sharp forward bending, and compression or burst fractures occur in the vertebral bodies at the junction of the thoracolumbar spine; the third is cumulative str...

AI Technical Summary

Problems solved by technology

However, in the actual clinical application process, it is found that metal materials have the following defects: (1) The elastic modulus is large, and significant stress shielding occurs during the treatment process, which is easy to cause osteoporosis, slow bone tissue recovery, and easy to cause secondary fractures, etc. Problems; (2) The biocompatibility of some metal materials is not good, which sometimes leads to inflammatory reactions; (3) Second operations are often required to remove them after recovery, which not only increases the pain of the patient's treatment, but also increases the patient's economic burden

However, the disadvantage of biomedical polymer fracture fixation materials is that their tensile strength and tensile modulus are much lower than those of metal materials, and cannot meet the requirements of fracture fixation in occasions with high strength requirements

Images