Synthetic method of saponin

Abstract

The invention belongs to the field of organic synthesis, and involves a synthesis method of saponin, and in particular a method to construct glycosidic bond in saponin. The method includes the following steps: directly reacting an excessive amount of aldose or ketose with aglycone in an appropriate organic solvent under the action of an acid catalyst and reflux temperature of 30 DEG C to obtain the target product of saponin.

Description

technical field

[0001] The invention belongs to the field of organic synthesis and relates to a construction strategy of glycosidic bonds in saponins. Background technique

[0002] Saponins are a special class of secondary metabolites, sugar moiety and triterpene, steroid or steroid alkaloid connected by glycosidic bonds conjugate. According to the structure of saponins, it can be divided into triterpenoid saponins, steroidal saponins and steroidal alkaloids. Saponin is a glycoconjugate of triterpenes and steroids that widely exists in nature and has a wide range of activities. Antibacterial, antiviral, hypoglycemic, prevent and treat cardiovascular disease, hypotensive, diuretic, anti-fatigue, antipyretic and analgesic, liver protection, etc., and can also be used as a natural food sweetener, protective agent, foaming agent, and flavor enhancer , antioxidants, etc. However, saponins always exist in a large family with similar structures in nature, which makes the separa...