The invention relates to a nanometer composite oxide ceramics binding aluminium-spinel fireproof casting material and a manufacturing method thereof. The composition of ingredients thereof is that various grades of special-class bauxite clinker, brown fused alumina, secondary white fused alumina, white fused alumina and aluminum-magnesium spinel are adopted as skeletal material; and the base material comprises plate-shaped corundum powder, calcinatory alpha-Al2O3 powder, active Al2O3 powder, aluminum-magnesium spinel powder, pure calcium aluminate cement, nanometer Al2O3-MgO composite ceramics binding agent hydrate colloid suspension bonding agent as well as various addition agents. The ingredients are mixed and stirred for making the nanometer Al2O3-MgO composite ceramics binding aluminium-spinel fireproof casting material. The fireproof casting material of the invention has excellent microstructure and mechanics performance, and also has the performances such as special slag corrosion resistance, stability of high temperature structure and high temperature resistance, and the like, is used in the entirely casting LF finery, and the service life thereof is prolonged obviously, and the development demands for effective operation of secondary refining equipment, thus providing the best service for the steal industry.