3D printed mask and manufacturing technology thereof

A 3D printing and preparation technology, applied in the field of skin care products, can solve the problems of long time-consuming, inactivation, cumbersome process, etc., and achieve the effect of simple method and short time-consuming

Inactive Publication Date: 2015-09-30
GUANGZHOU SALIAI STEMCELL SCI & TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above method is cumbersome and time-consuming, and a large part of the active ingredients in the mask will be inactivated after ...

Method used

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  • 3D printed mask and manufacturing technology thereof
  • 3D printed mask and manufacturing technology thereof

Examples

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preparation example Construction

[0049] The present invention has no special limitation on the preparation method of the above-mentioned facial mask liquid, and the preparation method of the facial mask liquid known to those skilled in the art will suffice. In the present invention, preferably adopt following method to carry out the preparation of mask liquid:

[0050] mixing the hyaluronic acid aqueous solution with the freeze-dried powder of the stem cell growth factor, and then mixing with the aqueous solution of the honeysuckle extract and the honey aqueous solution to obtain a mixed solution;

[0051] The mixed solution is sterilized by filtration and concentrated to obtain a mask liquid.

[0052] In the present invention, hyaluronic acid is first prepared into an aqueous solution, and the concentration of the hyaluronic acid aqueous solution is 1-5 μg / ml, preferably 2-4 μg / ml. After obtaining the hyaluronic acid aqueous solution, dissolve the stem cell growth factor freeze-dried powder with the hyaluro...

Embodiment 1

[0075] Preparation of Stem Cell Growth Factor

[0076] Obtain primary mesenchymal stem cells from autologous adipose tissue by enzymatic digestion. The process is as follows: adipose tissue solution obtained by liposuction, rinsed with PBS (phosphate buffered saline) for 2 to 3 times, and added BSA with a final concentration of 1 wt%. (bovine serum albumin) and collagenase type 1 with a final concentration of 0.1wt%, shake in a shaking incubator at 37°C for 30min; then add X-VIVO15 containing 10% (volume percent concentration) FBS (fetal bovine serum) Serum-free medium was used to stop the digestion; after that, the undigested tissue was filtered through an 80-mesh mesh, and the filtrate was centrifuged at 400 g for 10 min; finally, the upper three layers were discarded, and the adipose stem cells in the lower layer were the primary mesenchymal stem cells isolated in this example.

[0077] Primary mesenchymal stem cells were inoculated in LONZA X-VIVO15 serum-free medium conta...

Embodiment 2

[0080] Preparation of honeysuckle extract

[0081] First take honeysuckle powder, add 10 times the mass of 50wt% ethanol, extract twice at 80°C for two hours each time, combine the immersion solution and filter; then the filtrate is concentrated under reduced pressure, ethanol is recovered, and the pH of the concentrated solution is adjusted to about 2 , extracted four times with 4 times the amount of ethyl acetate, combined the extracts; then added an appropriate amount of water to the extracts to wash twice, adjusted the pH to 6-7 with 40wt% NaOH, allowed the layers to stand, and took the water layer; Finally, the water layer is pressurized and concentrated to a thick paste, and air-dried at room temperature to obtain the honeysuckle extract.

[0082] The composition of the above-mentioned honeysuckle extract was analyzed, and the results were as follows: the content of neochlorogenic acid was 4 wt%, the content of chlorogenic acid was 10 wt%, the content of caffeic acid was...

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Abstract

The invention provides a manufacturing technology of a 3D printed mask. The technology includes the following steps that under sterile vacuum conditions, according to human facial profiles, collagen gel and mask essence are sequentially stacked and printed through a 3D printer to obtain the 3D printed mask. The mask is manufactured through the 3D printing technology, the mask can be obtained by sequentially stacking and printing the collagen gel and the mask essence, the method is simple, and consumed time is short. Besides, the high-temperature process is not needed during printing, and effective components of the mask essence can be completely stored. Besides, a porous mask support is formed through the collagen gel in the vacuum condition, and the mask essence can be adsorbed to the largest extent. The obtained 3D printed mask is specialized according to individuation of the human facial profiles, and can completely fit with pores on human face skin.

Description

technical field [0001] The invention belongs to the technical field of skin care products, and in particular relates to a 3D printing facial mask and a preparation process thereof. Background technique [0002] Mask is a carrier of beauty care products, and it is applied on the face for 15 to 30 minutes. When the nutrients of the skin care products are slowly absorbed by the skin, the film is removed. Masks are used very frequently as daily skin care products, especially for women with a wide variety of masks and different functions. [0003] The Chinese patent with the application number 201510013546.5 discloses a preparation method of a complex polysaccharide bio-mask. The method takes konjac gum, sodium carboxymethyl cellulose, and calcium hydroxide according to the weight ratio, and uses purified water as a solvent to mix and stir the preparation , filled into molds, and then undergo high-temperature cooking, freezing, rinsing, sterilization, packaging, and inspection ...

Claims

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Application Information

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IPC IPC(8): A61K8/98A61K8/97A61K8/73A61K8/64A61K8/65A61Q19/00B33Y10/00
Inventor 陈海佳王一飞葛啸虎应杰万桦
Owner GUANGZHOU SALIAI STEMCELL SCI & TECH CO LTD
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