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Medicine for treating damp-heat type appendiceal abscess of infants and preparation method thereof

A technology for appendix abscess and damp-heat type, which is applied in the field of medicine and its preparation for treating damp-heat type appendix abscess in children, which can solve the problems of treating the symptoms but not the root cause, large side effects, affecting appetite, etc., and achieves definite curative effect, quick onset and short course of treatment Effect

Inactive Publication Date: 2015-11-04
JINAN SHUNHAO BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

And above-mentioned treatment affects appetite, treats the symptoms but not the root cause, and has great side effects

Method used

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Experimental program
Comparison scheme
Effect test

preparation example Construction

[0067] When the dosage form of the medicine is granules, its preparation method comprises the following steps:

[0068] The first step is to mix the raw medicinal materials of the medicine according to the stated proportion, add ethanol with an alcohol concentration of 85% to 95% relative to the mixture 4 to 8 times, heat to boiling and reflux for 3 to 5 hours, filter, and use osmotic The percolating method is slowly percolating at a rate of 1-2 ml per minute, collecting the percolating liquid, and then concentrating under reduced pressure under a vacuum of 0.06-0.09 Mpa to a paste with a relative density of 1.04-1.10 at 50-60 °C, spray drying , the inlet air temperature of the spray dryer is 160-175 °C, and the outlet air temperature is 80-85 °C, and then pulverized into powder to make dry paste powder;

[0069] In the second step, 0.2-0.4 times the mass of sucrose powder and 0.1-0.2 times the mass of the dry paste powder are added to the obtained dry paste powder to prepare ...

Embodiment 1

[0078] Example 1 Granules

[0079] The preparation process of the granules of the present invention is as follows: take 150g of Sapindus japonica, 30g of Guanzhong, 300g of Peilan, 220g of Houttuynia cordata, 120g of Fructus Acumensis, 340g of bellows root, 180g of velvety back thistle, 320g of bark of Catalonia, and golden thread Grass 440g, Bixie 270g, Cassia Seed 210g, Millennium Health 160g, Pandanus 300g, Muhe 220g, Guangzhu Qiong 420g, Baiyaozi 210g, Typhoid Herb 350g, Chuanpo Stone 150g, Wanggua Root 360g, Polygonum Polygonum 240g, Chenpi 150g , Guan Nanxiang 330g, Dung Kei Benedict 110g, Mallow 400g and Mai Nu 170g;

[0080] The first step is to mix the raw medicinal materials of the medicine according to the stated ratio, add 5 times alcohol concentration of 90% ethanol relative to the mixture, heat to boiling and reflux for 4 hours, filter, and use the percolation method at a rate of 2 ml per minute. Slowly percolating at a speed, collecting the percolating liquid, ...

Embodiment 2

[0082] Example 2 Capsules

[0083] The preparation process of the capsule preparation of the present invention is as follows: taking 180g of Sapindus japonica, 40g of Guanzhong, 250g of Peilan, 150g of Houttuynia cordata, 220g of A. Grass 340g, Bixie 300g, Cassia Seed 160g, Millennium Health 150g, Pandaula 320g, Muhe 200g, Light Rod Qiong 350g, Baiyaozi 200g, Typhoid Grass 340g, Chuanposhi 160g, Wanggua Root 280g, Polygonum 220g, Chenpi 180g , Guan Nanxiang 320g, Dung Kei Benedict 180g, Mallow 360g and Mai Nu 270g;

[0084] The first step is to mix the raw medicinal materials of the medicine in proportion, add ethanol with an alcohol concentration of 85% relative to the mass of the mixture, heat and reflux for 2 hours, extract, and filter to obtain a first extract; filter the obtained medicinal residues Then add 95% ethanol with an alcohol concentration of 1.5 times the quality of the medicinal residues, heat under reflux for 2 hours, extract, and filter to obtain a second ex...

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Abstract

The invention discloses a medicine for treating damp-heat type appendiceal abscess of infants and a preparation method thereof. The medicine comprises the following raw herbal materials: sapindus mukorossi, cyrtomium fortunei, smilax discotis, eupatorium fortunei, stellaria dichotoma, houttuynia cordata, elsholtzia penduliflora, buttonbush roots, cirsium vlassovianum, bark of kalopanax septemlobus, rubia membranacea, dioscorea tokoro, semen cassiae, homalomena occulta, pandanus tectorius, rodgersia aesculifolia, lepidogrammitis rostrata, kadsura heteroclita, eriophyton wallichii, oriental stephania root, vernonia cinerea, ventilago leiocarpa, Japanese snakegourd root, Indian damnacanthus herb, polygonum hydropiper, pericarpium citri reticulatae, myrrh, aristolochia koempeferi, stephania longa, malva sinensis and smut fungi of wheat. The medicine has the benefits as follows: the medicine has the efficacy of clearing away heat, eliminating dampness, activating blood to remove stasis, removing swelling and expelling pus, meanwhile, has the effects of promoting diuresis to eliminate dampness, invigorating the spleen, drying dampness, purging heat and relieving constipation, and has the advantages of quick action, high effective rate, definite curative effect, short treatment course, no toxic or side effects and low cost.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a medicine for treating damp-heat type appendix abscess in children and a preparation method thereof. Background technique [0002] Appendice abscess is due to acute appendicitis not diagnosed and treated in time, so that the appendix is ​​wrapped into an inflammatory mass by omentum adhesion, followed by appendix gangrene, perforation, and localized peritonitis to form appendix abscess. The common pathogen is Staphylococcus aureus. [0003] Clinical manifestations of appendix abscess: Most patients have right lower quadrant pain, or a history of metastatic right lower quadrant pain, and may have fever, nausea, and vomiting. There may also be mild diarrhea and other manifestations. In a small number of patients, the greater omentum oppresses the bowel, causing symptoms of incomplete intestinal obstruction. [0004] The treatment concept of traditional med...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61K36/896A61P1/00A61P31/04
Inventor 杜国强密夫丽
Owner JINAN SHUNHAO BIOTECH CO LTD
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