Liquid wound dressing

A wound dressing and liquid technology, which can be applied to medical preparations without active ingredients, skin diseases, and medical preparations containing active ingredients, etc., can solve the problems of poor gel flow performance, long time consumption, wound irritation, etc., To achieve the effect of reducing surface potential energy, reducing surface tension and increasing permeability

Inactive Publication Date: 2015-12-09
SHANDONG WEIGAO PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The wound debridement method is too cumbersome and time-consuming, and traditional disinfectants cannot effectively remove the biofilm that has formed on the wound surface
[0005] Chinese patent 201210203351.3 discloses a wound cleaning solution. The main active ingredient in this method is one or more of wormwood extract, aloe extract, and peppermint extract. The wound cleaning solution prepared by this method can effectively reduce the The stimulation of the wound is not easy to leave scars, but the wound cleaning solution prepared by this method can only achieve the antibacterial effect, and cannot effectively remove the biofilm on the wound surface
The method is a gel prepared from hyaluronic acid and its derivatives and nano-silver, the fluidity of the gel is poor, the liquid wound dressing cannot be used for wound debridement, and the gel prepared by this method has no resistance to penetration If the pressure is adjusted, the difference between the osmotic pressure of the product and the osmotic pressure of the wound and the wound surface will be too large, which will cause certain irritation to the wound.

Method used

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  • Liquid wound dressing
  • Liquid wound dressing
  • Liquid wound dressing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] 0.2 kg of chlorhexidine acetate, 0.9 kg of sodium chloride and 0.8 kg of phosphate were added to 98.1 kg of deionized water and stirred evenly to obtain a liquid wound dressing.

Embodiment 2

[0035] Add 0.1kg of povidone-iodine, 0.3kg of polyhexamethylene biguanide, 2.4kg of sodium chloride, 0.1kg of potassium chloride, and 3kg of sodium carbonate into 94.1kg of deionized water, and stir evenly to obtain a liquid wound dressing.

Embodiment 3

[0037] Add 0.2kg of chlorhexidine acetate, 0.5kg of benzalkonium bromide, 0.7kg of sodium chloride, 0.1kg of potassium chloride, 0.1kg of calcium chloride and 3.2kg of sodium borate into 95.2kg of deionized water, and stir to obtain a liquid wound dressing.

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PUM

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Abstract

The invention provides a liquid wound dressing. The liquid wound dressing comprises a 0.02-1.2 wt% of a disinfectant, 0.05-5 wt% of an osmotic pressure regulator and deionized water. The liquid wound dressing can kill pathogenic microorganisms in a wound in an extremely short period of time, remove a biological membrane formed on the wound surface and effectively inhibit re-formation of the biological membrane after wound debridement. The liquid wound dressing is convenient to use, and can synchronously finish debridement and disinfection of the wound, effectively kill the pathogenic microorganisms on the wound, maintain the osmotic pressure and the acid-alkali environment of the wound balanced, keep the wound wet, reduce irritation to the wound, promote occlusion of wounds, reduces the consumption of antibiotics and relieves the burden of a patient.

Description

technical field [0001] The invention belongs to the field of medical device dressings, in particular to a liquid wound dressing. Background technique [0002] In recent years, the widespread use of broad-spectrum antibiotics has led to changes in the distribution and drug resistance of wound infection bacteria. According to literature reports, the main pathogenic bacteria of nosocomial infection are Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa. Although the invention of antibiotics has improved our control of traumatic infections, antibiotics cannot completely prevent the occurrence of wound infections. [0003] In recent years, many studies at home and abroad have shown that most infected wounds will form bacterial biofilms, and there is an extremely important direct relationship between bacterial biofilms and bacterial drug resistance and wound healing. Biofilms have extremely strong Drug resistance an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K45/00A61K47/04A61P17/02A61P31/02
Inventor 杜武华林栋青刁盈盈
Owner SHANDONG WEIGAO PHARM CO LTD
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