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A kind of Chinese herbal medicine toothpaste containing nano diamondene

A nanodiamondene and Chinese herbal medicine toothpaste technology, which is applied in the field of oral hygiene and health care, can solve the problems of increasing the load of human excretion and processing drug residue components, reducing the original efficacy of drug ingredients, and uneven particle size of powder, so as to achieve continuous protection of oral hygiene , Relieve gum bleeding, increase the effect of staying time

Active Publication Date: 2018-05-18
ZHENGZHOU ARTIFICIAL DIAMOND & PROD ENG TECH RES CENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] 1. In the toothpaste containing fine powder of Chinese herbal plant tissue, due to the uneven particle size of the powder, it is difficult to effectively and evenly mix with other components in the toothpaste. As a result, it is difficult to fully contact with the oral tissue and reduce the actual efficacy
[0006] 2. In the toothpaste formula containing Chinese herbal medicine extracts, although it can be mixed evenly in the toothpaste formula, this kind of mixing is only physical mixing. In practice, it is taken away from the oral environment with the process of rapid tooth brushing and mouthwash. The ingredients stay in the mouth for a short time and cannot effectively release the drug effect
These medicinal ingredients will produce a certain degree of physical and chemical reactions after being mixed with other ingredients of the toothpaste, and the original efficacy of the medicinal ingredients will be reduced due to these reactions, thereby reducing the therapeutic effect of the medicine as a whole
[0007] 3. In order to achieve a certain effect, Chinese herbal toothpaste often contains a lot of Chinese herbal ingredients, which increases the load of human excretion and treatment of drug residues, and damages human body functions to a certain extent.

Method used

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  • A kind of Chinese herbal medicine toothpaste containing nano diamondene
  • A kind of Chinese herbal medicine toothpaste containing nano diamondene
  • A kind of Chinese herbal medicine toothpaste containing nano diamondene

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1 Preparation of nanodiamondene

[0030] Nanodiamondene was prepared by the following method:

[0031] (1) Preliminary crushing: Send the diamond raw material into the ball mill shaping barrel to crush and sieve out the particles above 70 mesh. The crushing time is 1-5 hours. The coarse material below 70 mesh is returned to the ball mill shaping barrel for re-crushing; The sieve machine sieves out fine materials with a mesh size of 800 mesh or more, and the vibrating time is 30 minutes to 2 hours, and the fine materials are repeatedly sieved more than once;

[0032] (2) Re-crushing: The fine material above 800 mesh screened is transported to the air flow crusher, the fine material is crushed by high-pressure airflow, and the fine powder above 8000 mesh is screened out, and the sieved residue is returned to the air flow crusher for re-crushing ;

[0033] (3) Pickling: First, put the fine powder above 8000 mesh in the mixture of concentrated sulfuric acid and...

Embodiment 2

[0038] A Chinese herbal medicine toothpaste containing nanodiamondene, prepared from the following raw materials in weight percentage: nanodiamondene (without surface functionalization treatment) 0.6%, honeysuckle extract and isatis root extract (the ratio of the two is 1: 1) 2%, friction agent 35%, hydroxyethyl cellulose 1.5%, carrageenan 1%, thickener 1.3%, sodium lauryl sulfate 2%, glycerin 11%, propylene glycol 8%, sweetener 0.5%, sorbic acid 0.6%, and the balance is deionized water.

[0039]Calcium hydrogen phosphate dihydrate and calcium hydrogen phosphate anhydrous salt are mixed at a ratio of 7:1 to prepare friction agent.

[0040] The above-mentioned Chinese herbal medicine toothpaste containing nanodiamondene is prepared according to the following steps:

[0041] (1) Use deionized water to fully mix nanodiamondene, Chinese herbal medicine extracts, carrageenan, and some thickeners in a shaker to prevent precipitation; (2) Mix abrasives, sweeteners, and hydroxyethyl ...

Embodiment 3

[0044] The difference between Example 3 and Example 2 is that: Example 3 uses surface functionalized nanodiamondene to prepare Chinese herbal medicine toothpaste. Specifically: a Chinese herbal medicine toothpaste containing nano-diamantene, which is prepared from the following raw materials in weight percentage: 0.6% nano-diamantene treated with surface functionalization, honeysuckle extract and isatis root extract (the ratio of the two is 1: 1) 2%, friction agent 35%, hydroxyethyl cellulose 1.5%, carrageenan 1%, thickener 1.3%, sodium lauryl sulfate 2%, glycerin 11%, propylene glycol 8%, sweetener 0.5%, sorbic acid 0.6%, and the balance is deionized water.

[0045] The nano-diamantene is treated with surface functionalization, and the treatment process is as follows: the nano-diamantene is placed in concentrated HNO with a mass ratio of 1:2 3 / Concentrated H 2 SO 4 In the mixed solution, heat and reflux at 90°C for 24 hours and then centrifuge to precipitate; take the pr...

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PUM

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Abstract

The invention discloses a Chinese herbal medicine toothpaste containing nano-diamondene, which belongs to the field of oral hygiene and health care. The ointment is prepared from the following raw materials in weight percentage: 0.3%-1.6% of nano-diamondene, 1%-4% of Chinese herbal medicine extract %, friction agent 18%~45%, hydroxyethyl cellulose 1.2%~2.3%, carrageenan 0.5%~2%, thickener 1%~4%, sodium lauryl sulfate 1.5%~3.5% , glycerin 8%~15%, propylene glycol 7%~10%, sweetener 0.5%~0.8%, preservative 0.5%~0.8%, and the balance is deionized water. The Chinese herbal medicine toothpaste containing nanodiamantene provided by the present invention is added with nanodiamantene, which can continuously kill bacterial colonies, and has more effective and lasting ability to protect oral hygiene than traditional Chinese herbal medicine toothpaste. The drug ingredients are distributed and stored regularly in the layered "storage room" of diamondene, and can achieve the effect of slow release, which greatly increases the residence time of the drug ingredients in the oral cavity and plays a role in continuous protection of oral hygiene.

Description

technical field [0001] The invention belongs to the field of oral hygiene and health care, and in particular relates to a Chinese herbal medicine toothpaste containing nano-diamondene. Background technique [0002] Oral health is a mirror that reflects life and health, but modern life is fast-paced and work pressure is high. Compared with other diseases such as heart disease and high blood pressure, oral health problems are said to be ignored by people, and there are even "toothaches" among the people. It is not a disease" wrong statement. The focus of oral health is to remove food residues and dirt, control bacterial colonies, enhance physiological stimulation, and make the oral cavity and dental system have a clean and healthy environment. [0003] Toothpaste is the most important cleaning product for oral hygiene in daily life. With the continuous development of new materials and the continuous improvement of technology levels, various types of toothpaste have also come...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/73A61K8/24A61K8/19A61Q11/00A61P1/02
CPCA61K8/19A61K8/24A61K8/731A61K8/97A61K2800/28A61Q11/00
Inventor 郭留希赵清国何本锋刘永奇杨晋中张建华武艳强邵静茹穆小娜
Owner ZHENGZHOU ARTIFICIAL DIAMOND & PROD ENG TECH RES CENT