Feed additive and preparation method and application thereof

A feed additive and animal feed technology, applied in applications, animal feed, animal feed, etc., can solve the problems of ineffective preservation of biologically active ingredients, easy mold growth in feed additives, and reduced animal immunity, so as to improve feed conversion rate and production performance, realize waste recycling, and enhance immunity

Inactive Publication Date: 2016-11-23
GUANGZHOU JINAN BIOMEDICINE RES & DEV CENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are many problems in the current use of feed additives. First, feed additives are prone to mold and deterioration, and cannot effectively preserve the biologically active ingredients contained in them, especially the ingredients such as probiotics and feed enzymes; secondly, Some feed additives are poorly absorbed in animals, especially additives containing biologically active ingredients, which are easily inactivated after being hydrolyzed by pepsin in the body; finally, feed additives are often used in excessive amounts, beyond the range, and beyond the time limit. Drug-resistant pathogenic bacteria and mutated pathogenic bacteria in the body continue to occur, animal immunity is reduced, and the disease is prone to complex

Method used

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  • Feed additive and preparation method and application thereof

Examples

Experimental program
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Example Embodiment

[0032] Example 1 Preparation of Bioactive Peptide Microcapsules

[0033] The bioactive peptide microcapsules of the present invention are respectively made of the following groups of preparation raw materials:

[0034]

[0035] Group A preparation method:

[0036] S1: Take 1g of chitosan, add acetic acid solution with a volume concentration of 1% to the chitosan according to the ratio of material to liquid 1:4, soak and swell for 60min, heat to dissolve at 45°C, add distilled water to make mass Volume concentration is 1% chitosan solution;

[0037] S2: Dissolve 4g of sodium alginate in water and stir until dissolved to make a sodium alginate solution with a mass volume concentration of 1%, then add 0.5g of casein phosphopeptide and 0.5g of antimicrobial peptide to the sodium alginate solution, and stir Until it is completely dissolved, solution A is obtained and set aside;

[0038] S3: Slowly drop solution A into 1% chitosan solution, add water to dilute to 2 times the v...

Example Embodiment

[0040] Example 2 Quality Detection of Bioactive Peptide Microcapsules

[0041] The appearance, average particle size, drug loading and encapsulation efficiency of the microcapsules prepared in groups A-E in Example 1 of the present invention were measured, and the results are shown in the table below.

[0042] Table 1 The quality test results of microcapsules of the present invention to enhance intestinal absorption of danshensu

[0043] group

[0044] The results showed that the microcapsules prepared in group B had high cysticity, smooth surface, the narrowest average particle size, and the highest drug loading and encapsulation efficiency, indicating that the microcapsules in group B were of better quality. The obtained microcapsules are used as bioactive peptide microcapsules in the feed additive preparation raw materials of the present invention.

Example Embodiment

[0045] The preparation of embodiment 3 feed additives

[0046] The feed additive of the embodiment of the present invention 3 is made up of the preparation raw material of following percentage by weight:

[0047] 40% moxa powder, 25% salina powder, 15% plant extract and 20% bioactive peptide microcapsules, wherein the plant extract is composed of the following preparation raw materials in percentage by weight: oregano 45%, cinnamon 30% and ebony 25%.

[0048] Preparation:

[0049] (1) Plant extract preparation:

[0050]S1: Dried oregano and cinnamon were crushed, added ebony plums, soaked in water for 1 hour according to the ratio of material to liquid ratio of 1:10, refluxed twice for 3 hours each time, filtered and retained the filter residue, combined the filtrate to obtain water extraction liquid;

[0051] S2: Add ethanol with a volume fraction of 8 times the total weight of the filter residue to the filter residue in step S1, which is 60%, reflux extraction twice, eac...

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Abstract

The invention belongs to the field of feed additives and particularly relates to a feed additive and a preparation method and application thereof. The feed additive provided by the invention is prepared from the following raw materials in percentage by weight: 30% to 40% of artemisia powder, 20% to 35% of dunaliella salina powder, 15% to 20% of plant extract and 15% to 25% of bioactive peptide microcapsules, wherein the plant extract is prepared from the raw materials: oregano, cinnamomum cassia and black plum, each bioactive peptide microcapsule is prepared from a capsule core and a capsule wall material which are in the weight ratio of (0.2 to 0.6) to 1, each capsule core is prepared from casein phosphopeptide and antibacterial peptide which are in the weight ratio of (1 to 4) to (0.5 to 2), and each capsule wall material is prepared from chitosan and sodium alginate which are in the weight ratio of 1 to (4 to 6). The feed additive provided by the invention can be used for promoting the growth of animals, increasing efficiency of feed utilization, enhancing the immunity of the animals, lowering disease infection rate and effectively preventing and treating diseases of livestock and poultry, is stable in quality, can be stored in long term and is not prone to mildewing.

Description

technical field [0001] The invention belongs to the field of feed additives, in particular to a feed additive and its preparation method and application. Background technique [0002] With the rapid development of my country's animal husbandry industry, people's demand for animal products has shifted from the initial quantity demand to the demand for quality and safety. Residues of harmful substances in livestock products are the main problem affecting the safety of livestock products, and feed additives are one of the main factors causing the residues of harmful substances to exceed the standard. [0003] As an important raw material in animal husbandry, feed additives play an important role in inventions such as animal production performance, enhancement of disease resistance, improvement of feed utilization efficiency, improvement of animal product quality and economic benefits. However, there are many problems in the current use of feed additives. First, feed additives ...

Claims

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Application Information

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IPC IPC(8): A23K10/37A23K10/30A23K20/147
CPCY02P60/87
Inventor 王一飞王巧利廖晓凤马婧
Owner GUANGZHOU JINAN BIOMEDICINE RES & DEV CENT
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