A kind of production method of quinolinic acid

Abstract

The invention provides a quinolinic acid production method. Quinolinic acid is produced through the following steps: preparing quinoline acid copper through an oxidizing reaction, treating an oxidation reaction mother liquid, preparing quinoline acid sodium through an alkaline hydrolysis reaction, decolouring, preparing quinolinic acid through an acid separation reaction, and treating an acid separation reaction mother liquid. The oxidation reaction mother liquid, alkaline hydrolysis reaction filter cake washing water and the acid separation reaction mother liquid are comprehensively and effectively treated; active ingredients, including copper ions, quinolinic acid and the like, in each mother liquid and washing water are recycled and are utilized into the production of the next batch of the quinolinic acid; the control on an acid separation reaction is optimized, and the yield of the quinolinic acid is improved. When the active ingredients are applied, the recycled copper oxide and the recycled basic copper carbonate are purified; the yield of the quinoline acid is improved; meanwhile, the purity of the quinoline acid is ensured; refining steps of the quinoline acid are reduced; the production cost is reduced. Through the treatment of each mother liquid and the application of the washing water, water resources are saved; the wastewater discharge is reduced; the pressure on the environment is relieved.

Description

Technical field [0001] The invention relates to a method for producing chemical raw materials, in particular to a method for producing quinolinic acid, and belongs to the technical field of chemical engineering. Background technique [0002] Quinolinic acid, also known as 2,3-pyridinedicarboxylic acid, is an important intermediate of pesticides, medicines and dyes. It can be used to synthesize fluorophenethyl ether, moxifloxacin, imidazolinone herbicides, and quinolone antibiotics; nicotinic acid obtained by decarboxylation of quinolinic acid at high temperature can be used to synthesize various hypertension, skin diseases and coronary heart diseases It can also be used as a drug intermediate to synthesize inositol nicotinate, isoniazid, etc. [0003] There are many production methods of quinolinic acid, including: 1. Quinoline oxidation method, which uses quinoline as raw material. The main oxidants are potassium permanganate, hydrogen peroxide, ozone and sodium chlorate; 2. Quin...

AI Technical Summary

Problems solved by technology

[0004] But, when adopting the quinoline oxidation method of prior art to produce quinolinic acid, the yield and the purity of quinolinic acid are low, need its refining

In the production process, there are effective components in the oxidation reaction mother liquor and the acid precipitation reaction mother liquor, which are usually discharged as wastewater after treatment, and the effective ingredients are lost in vain, which not only reduces the yield of quinolinic acid, but also increases the treatment of wastewater. difficulty

The prior art also has a simple method of applying mechanically, and the oxidation reaction mother liquor is applied mechanically to the production of the next batch of quinolinic acid. However, the impurity ions in the above two mother liquors are also introduced into the reaction system, which reduces the purity of the quinolinic acid.