Unlock instant, AI-driven research and patent intelligence for your innovation.

A pharmaceutical composition for increasing bone density, its preparation method and application

A technology for increasing bone density and composition, which can be used in drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as poor treatment effect and low absorption, and achieve guaranteed efficacy and enhanced bone density. Effect

Active Publication Date: 2020-06-23
ZHEJIANG ASEN PHARMA
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, estrogen drugs have the risk of inducing periuterine cancer, and calcium supplementation alone has the problem of low absorption, so most of the products have poor therapeutic effects

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A pharmaceutical composition for increasing bone density, its preparation method and application
  • A pharmaceutical composition for increasing bone density, its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] A pharmaceutical composition for enhancing bone density is prepared as follows:

[0064] Composition of raw materials: calcium carbonate 10g, D-glucosamine sulfate potassium salt 25g, collagen 15g, chondroitin sulfate 15g, casein phosphopeptide 0.5g, drynaria fortune extract 10g, panax notoginseng extract 10g;

[0065] Accessories: 10g starch, 15g lactose, 15g dextrin, 2g magnesium stearate;

[0066] Preparation:

[0067] Step 1: Pass the raw and auxiliary materials through an 80-mesh sieve respectively, crush the D-glucosamine sulfate potassium salt and then sieve, weigh according to the formula ratio, and set aside;

[0068] Step 2: Mix Rhizoma Drynariae extract, Panax notoginseng extract, and casein phosphopeptide uniformly to obtain mixed powder 1; then mixed powder 1, calcium carbonate, collagen, chondroitin sulfate, and D-glucosamine sulfate potassium salt , Starch, lactose, and dextrin are mixed for 15 minutes and mixed evenly to obtain the total mixed powder;

[0069] Ste...

Embodiment 2

[0073] A pharmaceutical composition for enhancing bone density is prepared as follows:

[0074] Composition of raw materials: calcium carbonate 25g, D-glucosamine sulfate potassium salt 20g, collagen 8g, chondroitin sulfate 8g, casein phosphopeptide 5g, Drynaria fortunei extract 5g, Panax notoginseng extract 5g;

[0075] Accessories: 15g starch, 2g lactose, 10g dextrin, 0.1g magnesium stearate;

[0076] Preparation:

[0077] Step 1: Pass the raw and auxiliary materials through an 80-mesh sieve respectively, crush the D-glucosamine sulfate potassium salt and then sieve, weigh according to the formula ratio, and set aside;

[0078] Step 2: Mix Rhizoma Drynariae extract, Panax notoginseng extract, and casein phosphopeptide evenly to obtain mixed powder 1; then mix powder 1, calcium carbonate, collagen, chondroitin sulfate, and D-glucosamine sulfate potassium salt , Starch, lactose, and dextrin are mixed for 30 minutes and mixed evenly to obtain the total mixed powder;

[0079] Step 3: Add ...

Embodiment 3

[0083] A pharmaceutical composition for enhancing bone density is prepared as follows:

[0084] Composition of raw materials: calcium carbonate 20g, D-glucosamine sulfate potassium salt 10g, collagen 5g, chondroitin sulfate 5g, casein phosphopeptide 2g, Drynaria fortunei extract 1g, Panax notoginseng extract 5g;

[0085] Accessories composition: starch 20g, lactose 10g, dextrin 5g, magnesium stearate 1g;

[0086] Preparation:

[0087] Step 1: Pass the raw and auxiliary materials through an 80-mesh sieve respectively, crush the D-glucosamine sulfate potassium salt and then sieve, weigh according to the formula ratio, and set aside;

[0088] Step 2: Mix Rhizoma Drynariae extract, Panax notoginseng extract, and casein phosphopeptide uniformly to obtain mixed powder 1; then mixed powder 1, calcium carbonate, collagen, chondroitin sulfate, and D-glucosamine sulfate potassium salt , Starch, lactose, and dextrin are mixed for 40 minutes and mixed evenly to obtain the total mixed powder;

[008...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a pharmaceutical composition having an effect of increasing bone density and a preparation method thereof. The pharmaceutical composition mainly comprises 10-25 parts by weight of calcium carbonate, 10-25 parts by weight of potassium D-glucosamine sulfate, 2-15 parts by weight of collagen, 5-15 parts by weight of chondroitin sulfate, 0.5 to 5 parts by weight of casein phosphopeptide, 1 to 10 parts by weight of rhizoma drynariae extract and 1 to 10 parts by weight of pseudo-ginseng extract. The pharmaceutical composition combines traditional Chinese herbal medicine characteristics and modern medical research. Through directly supplementing calcium, promoting calcium absorption, inhibiting excessive bone turnover and promoting osteoblast cell proliferation, bone density is improved.

Description

Technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition with the function of increasing bone density. The invention also relates to a preparation method of the pharmaceutical composition, belonging to the technical field of health food. Background technique [0002] Osteoporosis is a systemic bone disease characterized by osteopenia and destruction of the fine structure of bone tissue, which increases the fragility of bone and increases the risk of fracture. With the extension of human life span, the aging of the population brings new problems to human health. Osteoporosis and the fractures caused by it occupy the seventh place among the current common diseases, seriously threatening the health of middle-aged and elderly people. The medical profession has put the prevention and treatment of osteoporosis, the prevention of fractures, the treatment of hyperlipidemia, the prevention of myocardial infarction, the tre...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/01A61P19/10A61K36/258A61K33/10A61K31/726A61K31/7008
CPCA61K9/2059A61K31/7008A61K31/726A61K33/10A61K36/126A61K36/258A61K38/014A61K38/018A61K2300/00
Inventor 邓金明吴海英
Owner ZHEJIANG ASEN PHARMA