Tea polyphenol microcapsules with fixed-point release characteristics and application thereof

A technology for tea polyphenols and microcapsules, applied in the field of tea polyphenol microcapsules, can solve the problems of inability to effectively prevent damage, rapid loss of tea polyphenols, poor physiological compatibility, etc., and achieves perfect capsule shape, stable blood sugar, and easy access to materials. Effect

Inactive Publication Date: 2017-12-12
JIANGNAN UNIV
View PDF6 Cites 14 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These materials have their own limitations, such as complex process, easy residue, poor physiological compatibility, etc.
It has also been reported that the use of starch with high safety and good pore-forming properties to carry tea polyphenols can play a role similar to "embedding

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Tea polyphenol microcapsules with fixed-point release characteristics and application thereof
  • Tea polyphenol microcapsules with fixed-point release characteristics and application thereof
  • Tea polyphenol microcapsules with fixed-point release characteristics and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0044] Example 1

[0045] Preparation of modified starch: The modified starch prepared in this example is porous corn starch.

[0046] Accurately weigh 15g of dry base corn starch, place it in a 250 Erlenmeyer flask, add a certain amount of sodium acetate buffer to adjust the pH to 4.8, and configure it into a starch milk solution with a concentration of 20% (ie 200g / L) at a temperature of 50 Preheat in the water bath for 15 minutes. Accurately weigh 2.8% (the mass of the enzyme accounts for the percentage of the dry starch basis) of alpha amylase and glucoamylase, (1:2), where the enzyme activity of alpha amylase is 1500 U / g, and the enzyme activity of glucoamylase is 10 10,000 U / g, the dosage ratio of α-amylase and glucoamylase enzyme is 1:2, prepare enzyme solution with acetate buffer, transfer all enzyme solution to starch suspension and time accurately, and react in constant temperature oscillator After 16h, add 5ml of 40g / L sodium hydroxide solution to stop the reaction. C...

Example Embodiment

[0048] Example 2

[0049] When sodium alginate and chitosan are used as wall materials, the second embedding after the modified starch adsorbs tea polyphenols needs to consider the influence of the concentration of the chitosan solution on the embedding rate.

[0050] Add 1.5g of modified starch and 20ml of 25mg / ml tea polyphenol solution to the beaker, place it in a constant temperature water bath shaker at 20°C, and absorb at 110r / min for 60min. Take out the beaker, add 10ml of sodium alginate solution with a mass concentration of 0.05% (ie 0.5g / L) to it, mix well, drop in 25ml of a 1.2% calcium chloride solution (ie 12g / L) and use the volume fraction In a 25ml mixture of chitosan solutions with different mass concentrations (0.01%, 0.05%, 0.10%, 0.20%, 0.30%) prepared with 8% glacial acetic acid, adjusting the pH of the mixture to 3 has a great effect on the embedding effect. The impact is shown in Table 1.

[0051] Table 1 The effect of chitosan mass concentration on the embedd...

Example Embodiment

[0054] Example 3

[0055] Weigh 1.5g of the modified starch prepared in Example 1, and mix it with 25ml of 25mg / ml TP solution by shaking for 60min, then mix it with 0.15% (w / v) 10ml of sodium alginate solution and pump it in through a gear pump 25ml 0.1% (w / v) chitosan solution and 1.2% (w / v) CaCl 2 After reacting for 10 minutes in 25ml of the mixed solution, filter and collect and wash with distilled water three times, and then put the tea polyphenol carrier system into a vacuum drying oven at 40 degrees Celsius to dry to obtain the tea polyphenol carrier system. The tea polyphenol loading capacity of the loading system was 167.4 mg / g measured by the Folin method.

[0056] The tea polyphenol carrier system of this example was used to determine the release rate of tea polyphenols in the simulated intestinal juice after 0.5 h and 2.0 h of the simulated gastric juice by the Folin method.

[0057] Tea polyphenol release rate=Tea polyphenol content in intestinal juice / Tea polyphenol co...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The present invention discloses tea polyphenol microcapsules with fixed-point release characteristics and an application thereof, and belongs to the technical field of food. The present invention provides a constructed tea polyphenol carrier system with the fixed-point release characteristics by using modified starch as core material, combining sodium alginate and chitosan, and using a double layer embedding technology to protect the tea polyphenols from effects of a gastric environment and play functions of small intestines. An embedding rate of the prepared microcapsules is improved by 70% or above. After the fixed-point release of the tea polyphenols in the microcapsules, the tea polyphenol microcapsules can significantly realize a slow digestion of the starch and have a sustained release effect for postprandial blood glucose.

Description

technical field [0001] The invention relates to a tea polyphenol microcapsule with fixed-point release property and application thereof, belonging to the technical field of food. Background technique [0002] Tea polyphenols is a general term for a class of polyhydroxy compounds to exist in tea. It is a natural antioxidant substance with a variety of physiological activities. It has a good inhibitory effect on the enzymatic hydrolysis of starch and can help achieve Slow digestion and absorption, continuous release of energy, maintenance of postprandial blood sugar homeostasis, and prevention of various diet-related chronic diseases have become a research hotspot in the fields of food science and modern nutrition. However, tea polyphenols have poor stability, are sensitive to environmental factors, and are easily destroyed. Therefore, when the body directly ingests tea polyphenols, tea polyphenols are sensitive to the digestive environment, and the transport efficiency of tea...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A23L33/105A23L33/125A23P10/30A61K36/82A61K9/50A61K47/36A61P3/04
CPCA23L33/105A23L33/125A23P10/30A23V2002/00A61K9/5036A61K9/5073A61K36/82A23V2250/21A23V2250/5118A23V2200/328
Inventor 张根义刘天棋
Owner JIANGNAN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap