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Fermentation composition with effect of resisting lung cancer and preparation method of fermentation composition

A fermented composition and anti-lung cancer technology, which can be used in medical preparations containing active ingredients, drug combinations, anti-tumor drugs, etc., can solve problems such as large damage to the human body, and achieve inhibition of growth and proliferation, easy absorption, good treatment and assistance. effect of treatment

Inactive Publication Date: 2018-05-08
胡广
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the existing chemical anti-cancer drugs have a certain effect on inhibiting the proliferation of cancer cells, they are more harmful to the human body. How to find a drug that has less side effects on the human body and has an anti-cancer effect has become a more urgent problem. need

Method used

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Experimental program
Comparison scheme
Effect test

preparation example Construction

[0053] In the present invention, the preparation method of the fermented composition with anti-lung cancer effect specifically comprises the following steps:

[0054] a. Prepare medium mixed solution: weigh each component of medium according to the formula, mix and stir evenly, and prepare medium mixed solution;

[0055] b. Sterilization treatment: Introduce water vapor at 110-125°C into the culture medium mixture prepared in step a to carry out sterilization treatment;

[0056] c. Cooling: cool down the culture medium mixture treated in step b to 35-42°C;

[0057] d. Inoculation: in a sterile environment, add the mixed strains to the culture medium mixture treated in step c, stir the mixed solution at a constant temperature to complete oxygen consumption, and obtain a fermentation broth;

[0058] e. Static treatment: place the fermented liquid prepared in step d in a sealed container; keep the fermentation temperature in the tank at 35-42°C every day, discharge the gas in th...

Embodiment 1

[0062] A fermented composition with an anti-lung cancer effect, the fermented composition is made by fermenting a culture medium, and the culture medium includes the following components by weight percentage: 1% of Cordyceps mycelium, 3% of Korean ginseng, white ginseng Mustard Seed 1.5%, Agrimony 2%, Hakka 1%, Atractylodes Rhizoma 2%, Hedyotis diffusa 0.8%, Echinacea 2%, Peucedanum 0.5%, Plantain 1.5%, Imperata 0.5%, Perilla 0.5 %, Trichosanthes 0.2%, Shengnanxing 0.8%, Pinellia 0.2%, Morus alba 1%, carbon source 6%, nitrogen source 5%, fermentation strain 2%, and the balance is water; the carbon source is glucose , the nitrogen source is beef extract, and the fermentation strain is composed of Lactobacillus acidophilus (15wt%), Bifidobacterium cyanozoum (15wt%), Bifidobacterium bifidum (7wt%), Bifidobacterium breve (9wt%) %), Bifidobacterium infantis (12wt%), Bifidobacterium longum (6wt%), Streptococcus thermophilus (11wt%), Lactobacillus plantarum (8wt%), acetic acid bacter...

Embodiment 2

[0070] A fermented composition with anti-lung cancer effect, said fermented composition is made by fermenting a culture medium, said culture medium comprises the following components by weight percentage: Cordyceps mycelium 3%, Korean ginseng 2%, white Mustard Seed 2.5%, Agrimony 1%, Hakka 3%, Atractylodes Rhizome 1.5%, Hedyotis diffusa 1.5%, Echinacea 1%, Pedicure 1%, Plantain 0.8%, Imperata 1%, Perilla 0.2 %, Trichosanthes 0.5%, Shengnanxing 0.5%, Pinellia 0.5%, Morus alba 0.5%, carbon source 10%, nitrogen source 1%, fermentation strain 10%, and the balance is water; the carbon source is glucose , the nitrogen source is beef extract, and the fermented bacteria are composed of Lactobacillus acidophilus (13wt%), Bifidobacterium adolescentis (8wt%), Bifidobacterium animalis (15wt%), Bifidobacterium bifidum (5wt%) ) Bifidobacterium infantis (12wt%), Streptococcus thermophilus (5wt%), Lactobacillus plantarum (11wt%), Bacillus natto (12wt%), Bacillus licheniformis (6wt%), photosyn...

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Abstract

The invention relates to a fermentation composition with the effect of resisting lung cancer. The fermentation composition is prepared by fermentation of a culture medium, wherein the culture medium is prepared from the following components in percentage by weight: 1 to 3 percent of cordyceps sinensis , 2 to 3 percent of Korean ginseng, 1.5 to 2.5 percent of semen brassicae, 1 to 2 percent of agrimonia pilosa, 1 to 3 percent of radix rehmanniae, 1.5 to 2 percent of rhizoma atractylodis macrocephalae, 0.8 to 1.5 percent of herba hedyotidis diffusae, 1 to 2 percent of rhizoma paridis, 0.5 to 1 percent of rhizoma corydalis, 0.8 to 1.5 percent of plantain herb, 0.5 to 1 percent of rhizoma imperatae, 0.2 to 0.5 percent of fructus perillae, 0.2 to 0.5 percent of pericarpium trichosanthis, 0.5 to0.8 percent of arisaema erubescens, 0.2 to 0.5 percent of rhizoma pinelliae, 0.5 to 1 percent of cortex mori, 6 to 10 percent of a carbon source, 1 to 5 percent of a nitrogen source, 2 to 10 percentof fermentation strain and the balance of water. The invention further provides a preparation method of the fermentation composition. The fermentation composition disclosed by the invention has the advantages of better inhibitory effects on lung cancer cells, no side effects on a human body and simple preparation process.

Description

technical field [0001] The invention relates to the field of biological fermentation, in particular to a fermentation composition with anti-lung cancer effect and a preparation method thereof. Background technique [0002] Lung cancer is one of the malignant tumors with the fastest increasing morbidity and mortality and the greatest threat to the health and life of the population. In the past 50 years, many countries have reported that the morbidity and mortality of lung cancer have increased significantly. The incidence and mortality of lung cancer in men rank first among all malignant tumors, and the incidence and mortality of lung cancer occupy the second place in women. The etiology of lung cancer is still not completely clear. A large number of data show that long-term heavy smoking has a very close relationship with the occurrence of lung cancer. Although the existing chemical anti-cancer drugs have a certain effect on inhibiting the proliferation of cancer cells, the...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P35/00
CPCA61K36/068A61K36/12A61K36/258A61K36/284A61K36/31A61K36/428A61K36/535A61K36/605A61K36/66A61K36/68A61K36/73A61K36/748A61K36/804A61K36/8884A61K36/8888A61K36/896A61K36/899A61K2236/19A61K2300/00
Inventor 胡广李秋菊胡均霖
Owner 胡广
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