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A kind of medical degradable magnesium alloy suture thread and preparation method thereof

A magnesium alloy and suture technology, applied in medical science, surgery, coating, etc., can solve the problems of unsatisfactory suture effect, easy rupture, stress concentration, etc., to facilitate clinical suture operation, inhibit wound infection, and improve use. performance effect

Active Publication Date: 2021-02-05
苏州晶俊新材料科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at present, a single pure magnesium or magnesium alloy wire is used as a medical suture. In the actual use process, when the suture is knotted, its local deformation, stress concentration, and easy to break are likely to occur, resulting in final suture failure or poor suture effect. ideal

Method used

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  • A kind of medical degradable magnesium alloy suture thread and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] as attached figure 1 As shown, a medical degradable magnesium alloy suture is composed of five pure magnesium wires with a diameter of 0.52 mm and one pure magnesium wire with a diameter of 0.36 mm as the core, and degradable gelatin as the outer surface layer. , and its specific preparation process is as follows:

[0027] 1) Prepare pure magnesium into pure magnesium round wires with diameters of 0.52mm and 0.36mm;

[0028] 2) Perform fluoridation treatment on the pure magnesium wire obtained in step 1), select a solution whose main components are 2g / L sodium fluoride, 2g / L potassium fluoride and hydrofluoric acid, immerse the pure magnesium wire in the solution, soak For 12 hours, a dense porous ceramic layer rich in magnesium fluoride is formed on the surface in situ, with an average layer thickness of 5 μm;

[0029] 3) Take 5 pieces of 0.52mm diameter pure magnesium wire obtained in step 2) and 1 piece of 0.36mm diameter pure magnesium wire obtained in step 2), pl...

Embodiment 2

[0034] A medical degradable magnesium alloy suture, which is composed of four AZ61 magnesium alloy wires with a circumscribed circle diameter of 0.1 mm and a triangular cross-section wound as the core with a porous ceramic layer on the surface, and degradable polylactic acid as the outer surface layer. The specific preparation process as follows:

[0035] 1) Prepare the AZ61 magnesium alloy into a triangular wire with a circumcircle diameter of 0.1 mm;

[0036] 2) Perform micro-arc oxidation treatment on the AZ61 magnesium alloy wire obtained in step 1). The main components of the electrolyte are 13g / L sodium silicate, 5g / L sodium phosphate and 2.5g / L sodium hydroxide. AZ61 magnesium alloy wire is immersed in the electrolyte, and a pulse voltage of 380V is applied for 3 minutes to make the surface original. Form a dense porous ceramic layer rich in magnesium oxide, magnesium silicate, and magnesium phosphate, with an average layer thickness of 6 μm;

[0037] 3) Take 4 AZ61 m...

Embodiment 3

[0042] A medical degradable magnesium alloy suture, which is composed of seven Mg2Zn magnesium alloy wires with a diameter of 0.03 mm and a porous ceramic layer on the surface as the core, and degradable polyamide as the outer surface layer. The specific preparation process is as follows:

[0043] 1) Prepare the Mg2Zn magnesium alloy into a round wire with a diameter of 0.03mm;

[0044] 2) Perform micro-arc oxidation treatment on the Mg2Zn magnesium alloy wire obtained in step 1). The main components of the electrolyte are 10g / L sodium silicate, 3g / L sodium phosphate, 2g / L sodium hydroxide and 5g / L hydroxyapatite nanoparticles, and the Mg2Zn magnesium alloy wire is immersed in the electrolyte, and pulsed The voltage is 400V, and the time is 2 minutes, so that the dense porous ceramic layer rich in magnesium oxide, magnesium silicate, magnesium phosphate, and hydroxyapatite is formed on the surface in situ, with an average layer thickness of 4 μm;

[0045]3) Take 7 Mg2Zn magne...

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Abstract

The invention discloses a medical degradable magnesium alloy suture and a preparation method thereof. The suture is composed of 2 to 9 pure magnesium or magnesium alloy wires with a porous ceramic layer on the surface wound as a core, degradable gelatin or polymer As the outer surface layer composition. The preparation method is as follows: 2 to 9 pure magnesium or magnesium alloy wires with porous ceramic layers on the surface are wound into a suture thread by a wire winding device, and the outer surface of the suture thread is covered with a degradable gelatin or polymer layer. The medical degradable magnesium alloy suture thread of the present invention has higher strength and plasticity than pure magnesium or magnesium alloy wire with the same composition and diameter, has improved corrosion resistance, and meets medical needs.

Description

technical field [0001] The invention relates to the technical field of polymer composite materials, in particular to a medical degradable magnesium alloy suture and a preparation method thereof. Background technique [0002] At present, the commonly used metal medical sutures are made of titanium-nickel alloy wires, which have good chemical stability and excellent mechanical properties, and can meet the needs of clinical sutures such as intraepithelial, subcutaneous, and tendon operations, but the sutures cannot be degraded after surgery. The sutures need to be removed through a second operation, and it does not have antibacterial effect. The published patent CN201310191483.3 deposits a layer of silver ion plating with a thickness of 0.1-20 μm on the surface of the titanium-nickel memory alloy wire, which makes the titanium-nickel suture have antibacterial properties, but the problem of stitch removal is still unavoidable. [0003] In order to solve the problem of secondary...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L17/06A61L17/14
CPCA61L17/06A61L17/145
Inventor 白晶程兆俊邵怡
Owner 苏州晶俊新材料科技有限公司
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