Freeze-drying powder for improving dry and sensitive skin and preparation method thereof

A technology of freeze-dried powder and solvent, which is applied in the field of cosmetics, can solve the problems of not being able to guarantee whether there is still activity, not being able to improve the skin in an all-round way, and discounting product effects, so as to relieve skin redness, relieve seborrheic dermatitis, and ensure dispersion Effects of Sex and Uniformity

Active Publication Date: 2018-11-27
MELLGEN SHENZHEN BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the prior art, most of them are single or combination products of two cytokines, which directly lead to a relatively single efficacy of the product and cannot improve human skin in an all-round way.
At the same time, since the biologically active cell growth factor is directly added to the cosmetic base containing more complex ingredients, it is impossible to guarantee whether it will still be active after long-term mixing with the cosmetic base, and the effect of the product will be greatly reduced.

Method used

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  • Freeze-drying powder for improving dry and sensitive skin and preparation method thereof
  • Freeze-drying powder for improving dry and sensitive skin and preparation method thereof
  • Freeze-drying powder for improving dry and sensitive skin and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A kind of freeze-dried powder, its preparation steps are as follows:

[0029] (1) Weigh the following raw materials: 0.1 g of milk immune protein, 1 g of tetrahydromethyl pyrimidine carboxylic acid, 6 g of mannitol, and 85 g of phosphate buffer solution with a pH value of 6.8;

[0030] (2) Pre-disperse milk immune protein in an equal amount of glycerol, then add phosphate buffer, stir for 1 hour, and wait until the solution is translucent and free of granular substances; then add mannitol, tetrahydromethyl pyrimidine carboxylic acid , stirring and dissolving to obtain a mixed solution;

[0031] (3) Pre-freeze the prepared mixed solution in a -80°C refrigerator for 24 hours, then transfer to a vacuum freeze dryer for freeze-drying, turn off the machine after 48 hours, and take out the freeze-dried powder.

Embodiment 2

[0033] A kind of freeze-dried powder, its preparation steps are as follows:

[0034] (1) Weigh the following raw materials: 2 g of milk immune protein, 0.1 g of tetrahydromethyl pyrimidine carboxylic acid, 4 g of mannitol, and 95 g of phosphate buffer solution with a pH value of 7.4;

[0035] (2) Pre-disperse milk immune protein in an equal amount of glycerol, then add phosphate buffer, stir for 0.5 hours, and wait until the solution is translucent and free of granular substances; then add mannitol, tetrahydromethylpyrimidine carboxylate acid, stirring and dissolving to obtain a mixed solution;

[0036] (3) Pre-freeze the prepared mixed solution in a -80°C refrigerator for 48 hours, then transfer to a vacuum freeze dryer for freeze-drying, turn off the machine after 24 hours, and take out the freeze-dried powder.

Embodiment 3

[0038] (1) Weigh the following raw materials: 1 g of milk immune protein, 0.5 g of tetrahydromethylpyrimidine carboxylic acid, 4 g of mannitol, 1 g of trehalose, 1 g of glycine, and 92.5 g of phosphate buffer with a pH value of 6.8;

[0039] (2) Pre-disperse the milk immune protein in an equal amount of glycerol, then add phosphate buffer, stir for 0.5 hours, and wait until the solution is translucent and free of granular substances; then add mannitol, trehalose, glycine, four Hydromethylpyrimidine carboxylic acid, stirring and dissolving; finally adding the cell repair factor and stirring evenly to prepare a mixed solution, wherein the active concentration of the cell repair factor in the solution is 100 IU / mL;

[0040] (3) Pre-freeze the prepared mixed solution in a -80°C refrigerator for 48 hours, then transfer to a vacuum freeze dryer for freeze-drying, turn off the machine after 24 hours, and take out the freeze-dried powder.

[0041]The cell repair factor described in th...

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Abstract

The invention discloses freeze-drying powder for improving dry and sensitive skin and a preparation method thereof. The freeze-drying powder mainly contains milk immunoprotein, tetralin methyl pyrimidine carboxylic acid and cytothesis factors to inhibit inflammation signal factors such as IL-1, IL-6, IL-7 and TNF-a to balance the anti-inflammatory action, and scytitis of seborrheic dermatitis, contact dermatitis, eczema and the like can be effectively relieved; the releasing of histamine is inhibited to effectively relieve rubefaction and severe cutaneous pruritus; the cell lipid bilayer structure can be strengthened, the skin sebum barrier is reconstructed, the percutaneous water desorption of the skin is reduced, and the skin transdermal driage is normalized; the proliferation of skin cells can be rebalanced; the metabolism capacity of the cells is improved, the growth of basal cells is accelerated, the horn cell renewing is promoted, the separation of senescent and dying horn cellsform the skin tissue is accelerated, and therefore the pachulosis state is improved, and the surface of the skin is fine and smooth.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to a freeze-dried powder for improving dry and sensitive skin and a preparation method thereof. Background technique [0002] In recent years, biogenetic engineering technology has made great progress, and the beauty cosmetics industry has ushered in a new development opportunity, entering the era of biogenetic cosmetic cosmetics, mainly using a series of cell growth factors as the main functional ingredients, directly added to skin creams , body lotion, eye cream, skin care water, facial mask, repair essence and other cosmetics to achieve skin repair, anti-wrinkle, redness and other cosmetic effects. However, in the prior art, most of them are single or combination products of two cytokines, which directly lead to relatively single efficacy of the product and cannot comprehensively improve human skin. At the same time, since the biologically active cell growth factor is directly added to ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/64A61K8/49A61K8/02A61P17/00A61P17/04A61P17/08A61P29/00A61Q19/00
CPCA61K8/022A61K8/4953A61K8/64A61K2800/84A61Q19/005A61Q19/007A61P17/00A61P17/04A61P17/08A61P29/00
Inventor 阮仁全
Owner MELLGEN SHENZHEN BIOTECHNOLOGY CO LTD
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