Povidone iodine effervescent tablet used for animal delivery room and preparation method of povidone iodine effervescent tablet

A technology of povidone-iodine and effervescent tablets, which is applied to medical preparations with non-active ingredients, active ingredients of artificially synthesized polymeric materials, and pharmaceutical formulas. Treatment and prevention of animal umbilical cord infection, good economic value and social benefits, wide bactericidal effect

Inactive Publication Date: 2019-12-06
石家庄卫科生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In my country, the incidence of umbilical cord infection generally accounts for about 20% of the total incidence of newborn cattle and sheep, and the mortality rate can reach more than 80%. Umbilical cord infection will affect the growth and development of animals, making them lose their breeding value

Method used

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  • Povidone iodine effervescent tablet used for animal delivery room and preparation method of povidone iodine effervescent tablet
  • Povidone iodine effervescent tablet used for animal delivery room and preparation method of povidone iodine effervescent tablet
  • Povidone iodine effervescent tablet used for animal delivery room and preparation method of povidone iodine effervescent tablet

Examples

Experimental program
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Effect test

Embodiment 1

[0040] The present embodiment provides a povidone-iodine effervescent tablet used in the animal delivery room, which comprises the following components by weight percentage: 40% povidone-iodine, 17.5% citric acid, 10% sodium bicarbonate, polyethylene glycol Alcohol 6000 8%, microcrystalline cellulose 10%, anhydrous magnesium sulfate 12%, light magnesium carbonate loaded with BS-12 1.0%, sodium lauryl sulfate 0.5%, sodium carboxymethylcellulose 0.5%, Sodium chloride 0.5%.

[0041] The preparation method of the above-mentioned povidone-iodine effervescent tablet is as follows: get 12g of povidone-iodine powder and put it into an oven at 40° C. for drying for 4 hours. After drying, immediately pack the dried povidone-iodine powder into aluminum foil bag, and seal the aluminum foil bag to realize airtight storage in the dark, then mix 12g of povidone-iodine powder, 2.4g of polyethylene glycol 6000, and 3g of microcrystalline cellulose in a mixer for 10min after drying , mix well ...

Embodiment 2

[0043] The present embodiment provides a povidone-iodine effervescent tablet used in an animal delivery room, which comprises the following components by weight percentage: 20% povidone-iodine, 25% citric acid, 15% sodium bicarbonate, polyethylene glycol Alcohol 6000 4%, microcrystalline cellulose 18%, anhydrous magnesium sulfate 15%, light magnesium carbonate loaded with BS-12 1%, sodium lauryl sulfate 1%, sodium carboxymethylcellulose 0.3%, Sodium chloride 0.7%.

[0044] The preparation steps and the condition parameters involved in each step are the same as those in Example 1, and will not be repeated here.

Embodiment 3

[0046] The present embodiment provides a povidone-iodine effervescent tablet used in the animal delivery room, which comprises the following components by weight percentage: 50% povidone-iodine, 14% malic acid, 14.5% sodium bicarbonate, polyethylene glycol Alcohol 10000 5%, low-substituted hydroxypropyl cellulose 5%, anhydrous magnesium sulfate 10%, light magnesium carbonate loaded with BS-12 0.3%, sodium lauryl sulfate 0.2%, sodium carboxymethylcellulose 0.7%, sodium chloride 0.3%.

[0047] The preparation steps and the condition parameters involved in each step are the same as those in Example 1, and will not be repeated here.

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Abstract

The invention discloses a povidone iodine effervescent tablet used for an animal delivery room. The povidone iodine effervescent tablet is prepared from the following components in percentage by weight: 5-50% of povidone iodine, 5-30% of an acid source, 5-20% of an alkali source, 3-8% of a dissolving promoting agent, 5-20% of a disintegrating agent, 10-15% of a drying agent, 0.3-2.1% of a surfactant, 0.3-0.7% of a film-forming agent and 0.3-0.7% of a filler, wherein the sum of the weight percentages of the components is 100%. On the other hand, the invention further provides a preparation method of the povidone iodine effervescent tablet. The povidone iodine effervescent tablet disclosed by the invention has the characteristics of being high in dissolving speed, good in pharmaceutical effect, small in irritation, wide in bacteriocidal spectrum, safe in use, convenient to carry and the like, and can treat and prevent animal umbilical cord infection, and good economic value and social benefits can be created.

Description

technical field [0001] The invention relates to the field of animal disinfection medicines, in particular to a povidone-iodine effervescent tablet used in animal delivery rooms and a preparation method thereof. Background technique [0002] Umbilical cord infection is the most common disease in mammals. It is an inflammation caused by bacterial infection during umbilical cord cutting. It has become one of the problems that endanger newborn cattle and sheep. Infectious diseases of newborn cattle and sheep infected by umbilical cord generally include omphalitis and umbilical cord gangrene, cystitis, peritonitis, sepsis, pyelonephritis, lung abscess, liver abscess, suppurative meningitis, suppurative arthritis and tetanus. The pathogenic bacteria of umbilical cord infection mainly include Escherichia coli, Streptococcus, Staphylococcus, Pseudomonas aeruginosa, Streptococcus pneumoniae and Bacillus tetani. In my country, the incidence of umbilical cord infection disease general...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/46A61K47/10A61K47/38A61K31/79A61P31/04
CPCA61K9/0007A61K9/2031A61K9/2054A61K31/79A61P31/04
Inventor 钱雪桥王大伟杨迦王奎涛
Owner 石家庄卫科生物科技有限公司
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