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A method for preparing natural ferulic acid from soapstock containing oryzanol

A technology of oryzanol and ferulic acid, applied in the field of plant extraction and separation, can solve the problems of low purity, pollution, and complicated treatment

Active Publication Date: 2021-09-14
HUNAN HUACHENG BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0027] In order to overcome the defects of low extraction and preparation of natural ferulic acid in the prior art, low purity, pollution, complicated treatment, etc., the present invention provides a method for preparing natural ferulic acid using soapstock containing oryzanol as a raw material, which can be produced on an industrial scale White natural ferulic acid with a purity of more than 99%

Method used

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  • A method for preparing natural ferulic acid from soapstock containing oryzanol

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Experimental program
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Effect test

Embodiment 1

[0068] 1. Alkali-alcohol hot-melt filtration. 3m ahead 3 Add 1200L of edible ethanol with a concentration of 89% in the extraction tank, put 400kg of oryzanol-containing soapstock raw materials into the extraction tank under constant stirring, continue to add 1200L of edible ethanol with a concentration of 89%, keep stirring continuously and heat, and heat up to 52°C. The pH of the system was adjusted to 9.0 with a 6% dilute sodium hydroxide aqueous solution to dissolve the raw material, and the material was passed through a disc centrifuge while it was hot, and the filtrate was collected to obtain 2650 L of dissolved filtrate.

[0069] 2. Acid precipitation and separation. Adjust the pH of the dissolved filtrate to 6.5 with dilute sulfuric acid with a concentration of 5wt%, stir well, and let stand for 6 hours to make the oryzanol precipitate completely, and collect the centrifugal precipitate by a three-legged sedimentation centrifuge to obtain 261 kg of the centrifugal pre...

Embodiment 2

[0080] 1. Alkali-alcohol hot-melt filtration. 3m ahead 3 Add 1000L of edible ethanol with a concentration of 92% in the extraction tank, put 300kg of oryzanol-containing soapstock raw material into the extraction tank under constant stirring, continue to add 1000L of edible ethanol with a concentration of 92%, keep stirring and heating continuously, and heat up to 55°C. The pH of the system was adjusted to 10.0 with a 5% dilute sodium hydroxide aqueous solution to dissolve the raw material, and the material was passed through a three-legged sedimentation centrifuge while it was hot, and the filtrate was collected to obtain 2160 L of dissolved filtrate.

[0081] 2. Acid precipitation and separation. Adjust the pH of the dissolved filtrate to 7.0 with dilute hydrochloric acid with a concentration of 8 wt%, stir well, and let stand for 5 hours to make the oryzanol precipitate completely, and collect the centrifugal precipitate by a three-legged sedimentation centrifuge to obtain...

Embodiment 3

[0092] Others are the same as in Example 1, the difference is that the pH of the system is adjusted to 9.0 with dilute lye in step (1); the pH of the dissolved filtrate is adjusted to 7.0 with dilute acid in step (2); the alkali alcohol is adjusted with dilute sulfuric acid in step (6) The pH of the hydrolysis filtrate was 4.0. After testing, the finished product has a natural ferulic acid content of 98.73%, is pure white by visual inspection, and has a product yield of 82.31%.

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Abstract

A method for preparing natural ferulic acid from soapstock containing oryzanol, comprising the following steps: alkali-alcohol hot-melt filtration, acid precipitation separation, organic solvent decolorization at normal temperature, alkali-alcohol thermal reflux hydrolysis, cold analysis separation, acidification and cold storage Desalination, ultrafiltration membrane refining, alumina decolorization, solvent recovery, solid-liquid separation, drying, etc. to prepare natural ferulic acid. In the present invention, the content of oryzanol in the raw material is firstly increased to 50-70 wt%, and then hydrolyzed by hot-melting and refluxing with an alkali-alcohol solvent, and through the synergistic effect of purification and decolorization of oryzanol before hydrolysis and refining and decolorization of ferulic acid alcohol solution after hydrolysis, high-purity, pure White natural ferulic acid. The process of the present invention has the remarkable advantages of high yield, high purity, and complete decolorization; the reaction is milder than that of high-temperature concentrated alkali hydrolysis, the alkali concentration is lower, the dosage is less, and the conversion is complete; the production process is simple and the cost is low; The requirement of vanillin on the naturalness of raw materials has created obvious economic and social benefits.

Description

technical field [0001] The invention belongs to the technical field of plant extraction and separation, and relates to a method for preparing natural ferulic acid by using soapstock containing oryzanol as a raw material. Background technique [0002] Oryzanol exists in rice bran oil and is a mixture of ferulic acid esters mainly composed of triterpene (en) alcohols. It mainly acts on the autonomic nervous system and endocrine center of the diencephalon, can adjust autonomic nervous function, reduce endocrine balance disorders, and improve symptoms of mental and nervous disorders. It also has various physiological functions such as lowering blood lipids, reducing liver lipids, preventing lipid oxidation, and anti-oxidation. In addition, it also has the effect of resisting arrhythmia, which can reduce the excitability of myocardial muscle by regulating the function of autonomic nerves. The lipid-lowering effect of oryzanol can also improve the blood supply of the myocardium ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07C27/02C07C51/09C07C51/42C07C51/43C07C51/47C07C59/64
CPCC07C51/09C07C51/42C07C51/43C07C51/47C07C59/64
Inventor 黄华学刘庚贵刘永胜
Owner HUNAN HUACHENG BIOTECH
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