Lactobacillus plantarum capable of effectively relieving diabetes

A technology of Lactobacillus plantarum and diabetes, which is applied in the field of microorganisms, can solve problems such as insulin resistance and affect the health of patients, and achieve the effect of improving insulin resistance, no toxic side effects, and lowering blood sugar

Active Publication Date: 2020-06-19
UNIV OF SHANGHAI FOR SCI & TECH
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, there are two methods for diabetes treatment: one is insulin injection, but it may cause insulin resistance; the second is oral hypoglycemic drugs, but long-term use of dr

Method used

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  • Lactobacillus plantarum capable of effectively relieving diabetes
  • Lactobacillus plantarum capable of effectively relieving diabetes
  • Lactobacillus plantarum capable of effectively relieving diabetes

Examples

Experimental program
Comparison scheme
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Example Embodiment

[0019] Example:

[0020] (1) Preparation of culture medium

[0021] MRS liquid medium: peptone 10g, yeast extract 5g, diamine citrate 2g, beef extract 10g, glucose 20g, Tween-801mL, sodium acetate 5g, dipotassium hydrogen phosphate 2g, magnesium sulfate 0.58g, manganese sulfate 0.25g, agar Powder 15g, distilled water 1000mL.

[0022] MRS solid medium: add 15 g of agar to the MRS liquid medium, add 1000 mL of distilled water, and sterilize for use.

[0023] (2) Cultivation of probiotics

[0024] The probiotic strains were cultured in MRS liquid medium to the second generation, centrifuged, washed twice with sterilized distilled water and resuspended, and the concentration of the bacterial liquid was adjusted to 2 × 10 9 spare.

[0025] (3) Feeding and sample collection of rats

[0026] Feeding: 7-week-old SD rats were purchased, adapted for 1 week, and randomly divided into a model group and a normal group. The model group was fed with high-fat diet, and the normal group w...

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Abstract

The invention provides a Lactobacillus plantarum AR113 strain capable of effectively relieving diabetes. The Lactobacillus plantarum AR113 strain is preserved in the China General Microbiological Culture Collection Center on March 22, 2017, and the preservation number is CGMCC No. 13909. The Lactobacillus plantarum AR113 strain provided by the invention is capable of effectively relieving or eventreating diabetes, and playing roles of reducing blood sugar and improving insulin resistance.

Description

technical field [0001] The invention belongs to the field of microorganisms, and in particular relates to a plant lactobacillus capable of effectively alleviating diabetes. Background technique [0002] Diabetes is a serious chronic disease caused by the inability of the body to produce enough insulin or the inability of the cells to effectively use the insulin it produces. The typical symptom is high blood sugar concentration, which is mainly divided into 3 categories including: type Ⅰ, type Ⅱ, and pregnancy type. Among them, type II diabetes is the most common type, accounting for more than 90% of diabetic patients, and may even cause complications such as coronary heart disease, atherosclerosis, nephropathy, neuropathy, retinopathy, and foot lesions. At present, there are two methods for diabetes treatment: one is insulin injection, but it may cause insulin resistance; the second is oral hypoglycemic drugs, but long-term use of drugs will cause some side effects, such as...

Claims

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Application Information

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IPC IPC(8): C12N1/20A61K35/747A61P3/10A23L33/135C12R1/25
CPCA61K35/747A61P3/10A23L33/135A23V2002/00C12R2001/25C12N1/205A23V2400/169A23V2200/328
Inventor 艾连中王光强夏永军熊智强张汇
Owner UNIV OF SHANGHAI FOR SCI & TECH
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