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Chinese medicine formulation for regulating uric acid

A technology of traditional Chinese medicine preparations and uric acid, which is applied in the direction of medical preparations containing active ingredients, drug combinations, and pharmaceutical formulas. It can solve the problems of complex ingredients, unsystematic technology, and low drying efficiency, and achieve easy industrial production and component distribution ratio. Reasonable, low production cost effect

Inactive Publication Date: 2020-06-23
广西本草坊保健品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the technology of the present invention is not systematic, there are multiple dryings and the drying efficiency is low, and the low-temperature sterilization method used cannot kill bacterial spores, resulting in unstable product quality
[0005] Another example is that CNIO5663926A Chinese patent discloses a kind of uric acid-lowering plant enzyme and preparation method thereof: raw materials include fuzhuan black tea, green brick black tea, kombucha bacterial classification, pitaya red pulp, ripe papaya pulp, green papaya pulp, Grape fruit, psyllium seed gum, Zhugai kernel, Tuhuopu, Achyranthes bidentata, grass sage, Shiyingpu, cat's whiskers, peach blossom, peony bark, red peony root, angelica tail, silver flower vine, grape root, Guan The uric acid-lowering plant enzymes are produced by processing, fermenting, and ultra-high pressure sterilization of fragrant leaves. This method has a high operating pressure of up to 350MPa, high energy consumption, and complex components.
Fermentation prepares yeast to reproduce a large number of bacteria, and adopts ultra-high pressure and low temperature sterilization. This method has basically no effect on spore-bearing bacteria, so product safety has certain risks.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] A traditional Chinese medicine preparation for regulating uric acid, which consists of the following components in parts by weight: 5 parts of cloves, 2 parts of licorice, 3 parts of Chinese yam, 5 parts of poria cocos, 2 parts of medlar, 5 parts of hemp seed, 5 parts of purslane, and seabuckthorn 5 servings and 2 servings of cassia seeds.

[0017] The preparation method of the described Chinese medicine preparation of regulating uric acid, comprises the steps:

[0018] (1) Proportioning: take the above components by the above parts by weight;

[0019] (2) Pulverization: the raw material is first pulverized to 10um with a micro-powder pulverizer, and then pulverized to 50nm with a nano pulverizer;

[0020] (3) Slurry mixing: after nano-grinding, add pure water to the nano-powder at a ratio of 1:1.05, stir evenly, and measure the solid content at 48%;

[0021] (4) Enzymolysis: adding 1.2% ligninase by mass percentage and 2% cellulase by mass percentage. The reaction c...

Embodiment 2

[0029] A traditional Chinese medicine preparation for regulating uric acid, which consists of the following components by weight: 25 parts of cloves, 8 parts of licorice, 15 parts of Chinese yam, 18 parts of poria cocos, 10 parts of medlar, 20 parts of hemp seed, 25 parts of purslane, seabuckthorn 15 servings and cassia seed 15 servings.

[0030] The preparation method of the Chinese medicine composition for regulating uric acid comprises the steps of:

[0031] (1) Proportioning: take the above components by the above parts by weight;

[0032] (2) Pulverization: the prepared raw materials are first pulverized to 50um with a micro-powder pulverizer, and then pulverized to 200nm with a nano pulverizer;

[0033] (3) Slurry mixing: after nano-grinding, add purified water to the nano-powder at a ratio of 1:1.15, stir evenly, and measure the solid content at 45%;

[0034] (4) Enzymolysis: add ligninase with a mass percentage of 1.8% and cellulase with a mass percentage of 2-2.5%. ...

Embodiment 3

[0042] A traditional Chinese medicine preparation for regulating uric acid, which consists of the following components in parts by weight: 10 parts of cloves, 5 parts of licorice, 10 parts of Chinese yam, 10 parts of poria cocos, 6 parts of medlar, 10 parts of hemp seed, 10 parts of purslane, seabuckthorn 10 servings and cassia seed 10 servings.

[0043] The preparation method of the described Chinese medicine preparation of regulating uric acid, comprises the steps:

[0044] (1) Proportioning: take the above components by the above parts by weight;

[0045] (2) Pulverization: the prepared raw materials are first pulverized to 50um with a micro-powder pulverizer, and then pulverized to 200nm with a nano pulverizer;

[0046] (3) Slurry mixing: after nano-grinding, add purified water to the nano-powder at a ratio of 1:1.15, stir evenly, and measure the solid content at 45%;

[0047] (4) Enzymolysis: add ligninase with a mass percentage of 1.8% and cellulase with a mass percent...

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PUM

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Abstract

The invention belongs to the technical field of Chinese medicine research and development, and specifically to a Chinese medicine formulation for regulating uric acid and a preparation method thereof.The Chinese medicine formulation for regulating uric acid comprises the following components in parts by weight: 5-25 parts of flos caryophylli, 2-8 parts of radix glycyrrhizae, 3-15 parts of rhizomadioscoreae, 5-18 parts of poria, 2-10 parts of fructus lycii, 5-20 parts of fructus cannabis, 5-25 parts of herba portulacae, 5-15 parts of fructus hippophae, and 2-15 parts of semen cassiae. The Chinese medicine formulation of the present invention has a reasonable distribution ratio of each component and has a synergistic effect, and also has the advantages of good safety, no toxic and side effects, convenient drinking, and obvious effect of adjusting uric acid.

Description

technical field [0001] The invention belongs to the technical field of research and development of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation for regulating uric acid and a preparation method thereof. Background technique [0002] Gout is a disorder of purine metabolism, also known as "hyperuricemia", which belongs to a type of arthritis, also known as metabolic arthritis. It is a group of diseases caused by long-term purine metabolism disorder and increased blood uric acid that cause tissue damage. Gout is a metabolic disease caused by purine metabolism disorder, but its incidence has obvious heterogeneity. In addition to hyperuricemia, it can be manifested as acute arthritis, tophi, chronic arthritis, joint deformity, chronic interstitial nephritis and uric acid Sexual urolithiasis. Clinically, it can be divided into two categories: primary and secondary. Primary gout is mostly caused by congenital purine metabolism abnorma...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P19/06
CPCA61K36/076A61K36/185A61K36/482A61K36/484A61K36/60A61K36/61A61K36/815A61K36/8945A61P19/06A61K2300/00
Inventor 梁鹏曾梓强陆桂华黄琼连曾梓宁
Owner 广西本草坊保健品有限公司