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Dietary composition for preventing and treating hepatic sarcopenia and preparation method thereof

A technology of composition and diet, applied in the direction of drug combination, food science, active ingredients of heterocyclic compounds, etc., can solve the problems of hepatic sarcopenia, such as poor pertinence, poor patient compliance, and insignificant curative effect, and achieve liver protection function, susceptibility to hepatic encephalopathy, effect of prevention and treatment of hepatic sarcopenia

Pending Publication Date: 2020-09-01
THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In view of this, the present invention aims at the problems that the treatment measures for hepatic sarcopenia in patients with liver cirrhosis are not highly targeted, difficult to implement, poor patient compliance, and insignificant in curative effect, and provides a diet for preventing and treating hepatic sarcopenia Compositions and methods for their preparation

Method used

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  • Dietary composition for preventing and treating hepatic sarcopenia and preparation method thereof
  • Dietary composition for preventing and treating hepatic sarcopenia and preparation method thereof
  • Dietary composition for preventing and treating hepatic sarcopenia and preparation method thereof

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preparation example Construction

[0034] The invention also discloses a preparation method of a dietary composition for preventing and treating hepatic sarcopenia, comprising the following steps:

[0035] Step 1. Prepare black wolfberry, schisandra, and licorice extracts:

[0036] Step 1.1: Take fresh black wolfberry, dry and crush it at 55°C, accurately weigh the black wolfberry powder, add 50% ethanol according to 1:25 (g / mL), reflux extraction at 70°C for 3 times, 2h each time, concentrate under reduced pressure, freeze-dry That is the black wolfberry extract;

[0037] Step 1.2: Schisandra chinensis is dried at 60°C and pulverized, accurately weigh the schisandra chinensis powder, add 70% ethanol at a ratio of 1:10 (g / mL), reflux extraction at 80°C for 3 times, 2h each time, concentrate under reduced pressure, and freeze-dry. Schisandra extract;

[0038] Step 1.3: Grind the dried licorice, accurately weigh the licorice powder, add 60% ethanol at a ratio of 1:20 (g / mL), reflux at 70°C for 2 extractions, 1 ...

Embodiment 1

[0047] A dietary composition for preventing and treating hepatic sarcopenia, consisting of the following components in parts by mass: 5 g of black wolfberry powder extract, 5 g of schisandra powder extract, 2.5 g of licorice extract powder, 10 g of leucine, Amino acid 5g, lysine 1.5g, glutamine 5g, maltodextrin 10g, medium chain triglyceride 5g, vitamin C 200mg, vitamin E (α-TE) 10mg, vitamin B (B10.8mg, B2 0.8mg , B6 0.8mg, B12 1.36ug), vitamin D 6ug, selenium 30ug, zinc 8mg, magnesium 100mg.

[0048] The preparation method of the above-mentioned dietary composition for preventing and treating hepatic sarcopenia is as follows:

[0049] Step 1. Prepare black wolfberry, schisandra, and licorice extracts:

[0050] Step 1.1: Take fresh black wolfberry, dry and crush it at 55°C, accurately weigh the black wolfberry powder, add 50% ethanol according to 1:25 (g / mL), reflux extraction at 70°C for 3 times, 2h each time, concentrate under reduced pressure, freeze-dry That is the blac...

Embodiment 2

[0058] A dietary composition for preventing and treating hepatic sarcopenia, consisting of the following components in parts by mass: 10g of black wolfberry powder extract, 10g of schisandra powder extract, 3.5g of licorice extract powder, 15g of leucine, Amino acid 6g, lysine 2g, glutamine 8g, maltodextrin 15g, medium chain triglyceride 8g, vitamin C 300mg, vitamin E (α-TE) 15mg, vitamin B (B10.1mg, B2 0.1mg, B6 0.1mg, B12 1.7ug), Vitamin D 8ug, Selenium 40ug, Zinc 10mg, Magnesium 200mg.

[0059] The preparation method of the dietary composition for preventing and treating hepatic sarcopenia is the same as that in Example 1.

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Abstract

The invention discloses a dietary composition for preventing and treating hepatic sarcopenia and a preparation method thereof. The composition comprises the following components in parts by mass: 5-15parts of a black Chinese wolfberry powder extract; 5-15 parts of a schisandra chinensis powder extract; 2.5-5 parts of licorice root extract powder; 10-30 parts of leucine; 5-7.5 parts of arginine; 1.5-2.25 parts of lysine; 5-10 parts of glutamine; 10-30 parts of maltodextrin; 5-10 parts of medium chain triglyceride; 0.2-0.5 part of vitamin C; 0.01-0.02 part of vitamin E; 0.0024-0.0046 part of vitamin B; 6*10<-6>-10*10 <-6> parts of vitamin D; 3*10<-5>-5*10<-5> parts of selenium; 0.008-0.015 part of zinc; and 0.1-0.3 part of magnesium. The composition has the effects of protecting liver, resisting inflammation and resisting oxidation, cooperates with protein to promote muscle protein synthesis, and hinders muscular reduction.

Description

technical field [0001] The invention belongs to the technical field of nutritional diet and drug research and development, and in particular relates to a dietary composition for preventing and treating hepatic sarcopenia and a preparation method thereof. Background technique [0002] Malnutrition is an important complication in patients with chronic liver disease. According to comprehensive literature reports, the incidence rate is 65%-90% (①Caregaro L, Alberino F, Amodio P, et al. Malnutrition in alcoholic and virus-related cirrhosis [J]. The American Journal of Clinical Nutrition, 1996, 63 (4) :602-609. ② Kerwin A J, Nussbaum M S. Adjuvant Nutrition Management of Patients with Liver Failure, Including Transplant [J]. Surgical Clinics of North America, 2011, 91(3): 565-578.). Among hospitalized patients with cirrhosis, 81% had protein-energy malnutrition. The incidence of malnutrition in Child-Pugh class A and B cirrhosis patients is 21%-40%, and the incidence of malnutri...

Claims

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Application Information

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IPC IPC(8): A23L33/105A23L33/175A23L33/15A23L33/155A23L33/12A23L33/16A23L33/00A61K36/815A61K36/79A61K36/57A61P1/16A61P21/00A61K31/198A61K31/718A61K31/375A61K31/355A61K31/59A61K33/04A61K33/30A61K33/06A61K31/51A61K31/525A61K31/4415A61K31/714
CPCA23L33/105A23L33/175A23L33/15A23L33/155A23L33/12A23L33/16A23L33/00A61K36/12A61K36/815A61K36/79A61K36/57A61K36/484A61K31/198A61K31/718A61K31/375A61K31/355A61K31/59A61K33/04A61K33/30A61K33/06A61K31/51A61K31/525A61K31/4415A61K31/714A61P1/16A61P21/00A23V2002/00A61K2300/00A23V2200/30A23V2200/316A23V2250/21A23V2250/0628A23V2250/0606A23V2250/063A23V2250/062A23V2250/5114A23V2250/1944A23V2250/708A23V2250/712A23V2250/71A23V2250/1626A23V2250/1642A23V2250/161A23V2250/7042A23V2250/7044A23V2250/7052A23V2250/706
Inventor 廖侠贾庆安卜阳
Owner THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV
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