Vitamin A acetate microcapsule and preparation method thereof

Abstract

The invention discloses a vitamin A acetate microcapsule and a preparation method thereof. The method comprises the following steps: uniformly mixing gelatin with sugar, an emulsifying agent, a thickening agent, metal inorganic salt and water, adding vitamin A acetate molten oil containing an antioxidant, performing high-speed shearing, performing high-pressure homogenizing emulsification and performing micron filtration to obtain an emulsion; performing spray drying on the obtained emulsion, and embedding emulsion droplets in starch to obtain microcapsule particles; and performing drying, screening and crosslinking to obtain the vitamin A acetate microcapsule. According to the preparation method, emulsion preparation is mainly improved, so that particle size distribution is more uniform,the embedding effect on the vitamin A is better, the loss rate of vitamin A acetate is low in the spray drying process, the particle uniformity is good, the embedding effect is good, and the product storage stability is high. Especially, the metal inorganic salt added into the formula can promote crosslinking, effectively reduce the crosslinking temperature and shorten the crosslinking time.

Description

technical field [0001] The invention belongs to the technical field of vitamin A, and relates to a vitamin A acetate microcapsule and a preparation method. Background technique [0002] Vitamin A (vitamin A), also known as retinol (its aldehyde derivative retinal) or anti-dry eye factor, is an unsaturated monohydric alcohol with an alicyclic ring. Vitamin A can enhance the sensitivity of the human eye to low light, so that it can see things in a dark place with a certain illumination; it can maintain the health of epithelial tissue cells and promote the synthesis of immunoglobulin; it can promote the biosynthesis of proteins and the differentiation of bone cells. Maintain the normal growth and development of bones; contribute to cell proliferation and growth, promote growth and reproduction; and have the effect of delaying or preventing precancerous lesions, preventing chemical carcinogens, inhibiting tumor growth, and delaying aging; it can also be used as a nutritional sup...

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Problems solved by technology

However, this method does not add an emulsifier when configuring the emulsion, resulting in a large particle size, poor fluidity, and high viscosity. The use of a pressure atomizer requires the use of a high-pressure metering pump, and because the nozzle aperture is small, the emulsion must pass through Strict filtration, otherwise it is easy to block the nozzle, and the nozzle wears a lot, so it is not suitable for high-viscosity materials and large-scale production

[0008] There are corresponding defects in the above-mentioned methods, less attention is paid to the preparation of the emulsion, and the temperature required for cross-linking is too high, VA acetate in the cross-linking process The loss in the medium is relatively large, and a new preparation process needs to be found

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