Acidic skin-care hydrogel formula and preparation method thereof

A skin care water and acid technology, which is applied in skin care preparations, pharmaceutical formulations, cosmetic preparations, etc., can solve the problems of high production equipment requirements, complicated operation steps, and low salicylic acid content.

Inactive Publication Date: 2021-03-30
嘉兴睿肤丽生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Even if it exists, for example, patent application CN105188650 A (named soothing cosmetic composition based on salicylic acid), patent application CN105147596A (named water-soluble supramolecular salicylic acid hydrogel technology), patent application CN110013441A (named for enhancing Aqueous solution of dissolving salicylic acid, its preparation method and cosmetic composition containing it) and patent application CN108403458A (a kind of powerful anti-acne skin care cosmetic and preparation method), although all prepared different formulations containing salicylic acid, but their The content of salicylic acid is low, which is not conducive to the addition and use of salicylic acid in finished cosmetic products; moreover, its production raw materials and processes are relatively complicated, and it needs strong alkali neutralization or ultrasonic treatment, and silica air hydrogel encapsulation. Vacuum treatment, high requirements on production equipment, neutralized salicylic acid cannot play its role, and the operation steps are cumbersome

Method used

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  • Acidic skin-care hydrogel formula and preparation method thereof
  • Acidic skin-care hydrogel formula and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Composition formula

[0028] Element Mass percentage (%) polyethylene glycol-8 3 Poloxamer 407 4 glycerin 3 Salicylic Acid Nanogel 50 1,3-Butanediol 3 Menthol 0.3 water 36.7

[0029] The preparation steps of this embodiment are as follows:

[0030] 1. Weigh 3% polyethylene glycol-8, 4% poloxamer 407, 3% glycerin, 3% 1,3-butanediol, 36.7% deionized water according to the formula ratio, disperse evenly and heat to 85 Mix and stir at a certain speed at -90°C to dissolve until uniform, keep warm for half an hour and then stir to cool down;

[0031] 2. Add the pre-prepared 50% salicylic acid nanogel at 50-60°C, and stir slowly;

[0032] 3. Weigh 0.3% dipotassium glycyrrhizinate according to the proportion of the formula, add it at 45°C, stir and dissolve evenly at a certain speed, and then continue to cool down.

[0033] 4. Stir evenly and then cool down to room temperature to obtain a colorless, transparent to tra...

Embodiment 2

[0035] Composition formula

[0036] Element Mass percentage (%) polyethylene glycol-8 2 Polyacrylate-1 8 Diglycerin 5 citric acid 3 Betaine 4 Menthol 0.2 water 77.8

[0037] The preparation steps of this embodiment are as follows:

[0038] 1. Weigh 2% polyethylene glycol-8, 8% polyacrylate-1, 5% diglycerin, 4% betaine, and 77.8% deionized water according to the proportion of the formula, disperse evenly and heat to 85-90°C in Mix and stir at a certain speed to dissolve until uniform, keep warm for half an hour and then stir to cool down;

[0039] 2. Add 3% citric acid at 50-60°C, and stir slowly;

[0040] 3. Weigh 0.2% menthol according to the proportion of the formula, add it at 45°C, stir and dissolve evenly at a certain speed, and then continue to cool down.

[0041] 4. Stir evenly and then cool down to room temperature to obtain a colorless, transparent to translucent skin care hydrogel through degassing.

Embodiment 3

[0043] Composition formula

[0044]

[0045] The preparation steps of this embodiment are as follows:

[0046] 1. Weigh 3% polyethylene glycol-8, 3% PEG-240 / HDI copolymer bis-decyl tetradeceth-20 ether, 3% betaine, 65.7% deionized water according to the formula ratio, and disperse After uniformity, heat to 85-90°C, mix and stir at a certain speed to dissolve until uniform, keep warm for half an hour and then stir to cool down;

[0047] 2. Add the pre-prepared 20% salicylic acid nanogel at 50-60°C, and stir slowly;

[0048] 3. Weigh 0.3% dipotassium glycyrrhizinate and 5% aloe barbadensis leaf extract according to the proportion of the formula, add them at 45°C, stir and dissolve evenly at a certain speed, and then continue to cool down.

[0049] 4. Stir evenly and then cool down to room temperature to obtain a colorless, transparent to translucent skin care hydrogel through degassing.

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Abstract

The invention provides an acidic skin-care hydrogel formula and a preparation method thereof. The acidic skin-care hydrogel formula comprises 1-30% of acid, 1-30% of a thickening agent, 1-30% of a humectant, 20-80% of deionized water and 0-10% of an anti-allergic soothing agent. The acidic skin-care hydrogel disclosed by the invention is thickened by a nonionic or cationic high-molecular polymer,the used acid is free acid, and the pH value of the final product is 2-3. The acidic skin care hydrogel has the advantages of high acid content, good gel formability, good stability, small irritation,convenience in use and the like, and the preparation method is simple, controllable and good in repeatability. The problems that an acid system is difficult to thicken and use are solved, irritationof acid substances to the skin is remarkably reduced, and the technical problems that an aqueous solution is inconvenient to use and prone to diffusion due to the fact that the aqueous solution cannotstay are well solved. The effects of anti-inflammation, keratinocyte conditioning, inflammation relieving, skin appearance improving and skin cell metabolism enhancing of the acid active ingredientsare better achieved, and in addition, the effects of moisturizing, whitening, oil controlling, pore cleaning and shrinking, allergy resisting and dandruff removing are further achieved in cooperationwith other active ingredients.

Description

technical field [0001] The invention relates to a formula and a preparation method of an acidic skin care hydrogel in the cosmetic formula preparation technology. Background technique [0002] Acid is a common component in skin external products, and acid preparation is the most effective chemical peeling method except for medical cosmetology. The acidic preparation can controlly destroy a certain layer of skin, promote epidermal regeneration and dermal reconstruction, so as to achieve the treatment of skin blemishes located in the epidermis or superficial dermis. Acids commonly used topically on the skin are fruit acids (AHAs) and salicylic acid (BHA). AHAs were first used in dermatology in 1974. AHAs used in dermatology include citric acid, lactic acid, glycolic acid, lactobionic acid, etc. Salicylic acid, also known as β-hydroxy acid (BHA), exists in many plants, such as willow bark, sweet birch bark and white pearl tree. It has a long history of application and is wid...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/34A61K8/9794A61K8/86A61K8/63A61K8/44A61K8/368A61K8/365A61K8/04A61Q19/00
CPCA61K8/368A61K8/365A61K8/86A61K8/345A61K8/34A61K8/63A61K8/9794A61K8/44A61K8/042A61Q19/00A61K2800/262A61K2800/48
Inventor 夏强李建彤
Owner 嘉兴睿肤丽生物科技有限公司
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