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Calcium, vitamin D and vitamin K tablet and preparation method thereof

A vitamin and tablet technology, applied in the directions of pill delivery, pharmaceutical formulations, aluminum/calcium/magnesium active ingredients, etc., can solve the problems of poor stability, increased cost, low retention rate, etc., and achieves good tableting quality and production cost. The effect of low, high content

Pending Publication Date: 2021-06-18
郑州路路通医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] due to vitamin D 3 Very poor stability, sensitive to light, heat, oxygen, easy to degrade, and the existing calcium vitamin D 3 Production of tablets for vitamin D 3 Low retention rate, need to add more vitamin D 3 To ensure calcium vitamin D 3 Vitamin D in Tablets 3 The content reaches the standard, and the cost increases

Method used

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  • Calcium, vitamin D and vitamin K tablet and preparation method thereof
  • Calcium, vitamin D and vitamin K tablet and preparation method thereof
  • Calcium, vitamin D and vitamin K tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1: design a kind of calcium vitamin D vitamin K tablet, comprise the raw material of following parts by weight and make: calcium carbonate 275 parts, vitamin D 3 6 parts, 10 parts of starch sodium octenyl succinate, 50 parts of gum arabic, 23 parts of soybean oil, 0.015 parts of mixed tocopherol concentrate, 8 parts of tricalcium phosphate, 0.3 parts of sodium ascorbate, 260 parts of folic acid, fermented vitamin K 2 90 parts of powder, 7 parts of maltodextrin, 7 parts of magnesium stearate, and 8 parts of coating premix.

[0029] In the present embodiment, the fermented vitamin K 2 Powder comprises the raw material of following weight part: edible cornstarch 25 parts, ethyl cellulose 8 parts, vitamin K 2 35 parts, 5 parts of sodium caseinate, 4 parts of mono- and diglycerin stearate, 1 part of aspirin palmitate.

[0030] In the present embodiment, the fermented vitamin K 2 The fermentation steps of powder include:

[0031] S1, fermentation medium formula...

Embodiment 2

[0044] Embodiment 2: Design a kind of calcium vitamin D vitamin K tablet and comprise the raw material of following parts by weight and make: calcium carbonate 300 parts, vitamin D 3 7 parts, 11 parts of starch sodium octenyl succinate, 40 parts of gum arabic, 22 parts of soybean oil, 0.015 parts of mixed tocopherol concentrate, 8 parts of tricalcium phosphate, 0.3 parts of sodium ascorbate, 260 parts of folic acid, fermented vitamin K 2 90 parts of powder, 7 parts of maltodextrin, 7 parts of magnesium stearate, and 8 parts of coating premix.

[0045] Embodiment 1-2 test and result:

[0046] Table 1 Sensory Requirements

[0047]

[0048] Table 2 Physical and Chemical Requirements

[0049]

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Abstract

The invention discloses a calcium, vitamin D and vitamin K tablet and a preparation method thereof. The tablet comprises the following raw materials of, in parts by weight, 200-400 parts of calcium carbonate, 34.8-10.8 parts of vitamin D, 10-12 parts of starch sodium octenylsuccinate, 40-60 parts of arabic gum, 20-25 parts of soybean oil, 0.015-0.2 part of a mixed tocopherol concentrate, 0.6-10 parts of tricalcium phosphate, 0.2-0.4 part of sodium ascorbate, 200-400 parts of folic acid, 80-100 parts of fermented vitamin K2 powder, 5-10 parts of maltodextrin, 5-10 parts of magnesium stearate and 5-10 parts of coating premix. The calcium, vitamin D and vitamin K tablet is high in stability and uniformity and easy to absorb by a human body, a preparation method is simple, production cost is low, and the produced calcium, vitamin D and vitamin K tablet is beneficial to absorption by the human body.

Description

technical field [0001] The invention relates to the technical fields of biomedicine and health food, in particular to a calcium vitamin D vitamin K tablet and a preparation method thereof. Background technique [0002] Calcium is necessary to maintain the normal function of human nerves, muscles, skeletal system, cell membrane and capillary permeability. It is also the most abundant mineral element in the body. It participates in the entire life process of the human body, from bone formation, muscle contraction, heart beating, nerve and brain thinking activities, to the growth and development of the human body, eliminating fatigue, strengthening the brain and improving intelligence, and delaying aging. Can not do without calcium. Sufficient calcium intake every day can maintain the normal metabolism of the human body and enhance the adaptability of the human body to the living environment. The calcium content in the adult body accounts for about 1.5% to 2.0% of the body we...

Claims

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Application Information

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IPC IPC(8): A23L33/16A23L33/155A23L33/15A23P10/28A23P10/30A61K33/10A61K31/593A61K31/122A61K9/36A61P3/02
CPCA23L33/16A23L33/155A23L33/15A23P10/28A23P10/30A61K33/10A61K31/593A61K31/122A61K9/2059A61K9/2866A61P3/02A23V2002/00A23V2250/1578A23V2250/7106A23V2250/7144A23V2200/30A61K2300/00
Inventor 吕晓鹏
Owner 郑州路路通医药科技有限公司
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