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Nano organic selenium tablet and preparation method thereof

A nano-organic and tablet technology, which is used in food ultrasonic treatment, ultra-high pressure food processing, yeast-containing food ingredients, etc. selenium content and other issues, to achieve the effect of improving precipitation conditions, full of energy, and improving solubility

Pending Publication Date: 2021-10-22
WEIHAI TERENCE BIO ENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, selenium tablets on the market only pay attention to the content of selenium, but do not pay attention to the form of selenium and its bioavailability and product stability. The role of selenium compounds in the human body is very different. The human body absorbs selenium in many inorganic forms, and it is also toxic. Eating this selenium will not bring beneficial health effects to people.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Harvesting functional selenium-enriched yeast with a selenium content of 2000PPm for subsequent use;

[0026] Weigh the above-mentioned selenium-enriched yeast, dissolve it in water, and make a slurry with a concentration of 13%, then add the slurry to an ultrasonic breaker, and ultrasonicate for 20 minutes with a power of 200w to further refine the particles, and then pass ultra-high pressure homogenization Homogenize the slurry twice under the conditions of pressure of 120mpa and temperature of 65°C, carry out nano-processing on the selenium-enriched yeast slurry, and then undergo centrifugal spray drying, rapid solidification, and granulation to prepare nano-organic selenium powder for future use. ;

[0027] Harvest commercially available food grade L-ascorbic acid, vitamin K2 (fermentation method), D-alpha-tocopheryl succinate, sorbitol, lactose, silicon dioxide, microcrystalline cellulose, povidone, magnesium stearate ,spare;

[0028] Weigh 157 parts of raw mater...

Embodiment 2

[0031] Harvesting functional selenium-enriched yeast with a selenium content of 2000PPm for subsequent use;

[0032] Weigh the above-mentioned selenium-enriched yeast, dissolve it in water, and make a slurry with a concentration of 10%, then add the slurry to an ultrasonic breaker, and ultrasonicate for 20 minutes with a power of 200w to further refine the particles, and then pass ultra-high pressure homogenization quality machine, the slurry is homogenized twice under the conditions of pressure of 120mpa and temperature of 55°C, the selenium-enriched yeast slurry is subjected to nano-processing, and then centrifugal spray drying, rapid solidification, and granulation to obtain nano-organic selenium powder for future use ;

[0033] Harvest commercially available food grade L-ascorbic acid, vitamin K2 (fermentation method), D-alpha-tocopheryl succinate, sorbitol, lactose, silicon dioxide, microcrystalline cellulose, povidone, magnesium stearate ,spare;

[0034] Weigh 156 part...

Embodiment 3

[0037] Harvesting functional selenium-enriched yeast with a selenium content of 2000PPm for subsequent use;

[0038] Weigh the above-mentioned selenium-enriched yeast, dissolve it in water, and make a slurry with a concentration of 11%, then add the slurry to an ultrasonic breaker, and ultrasonicate it with a power of 200w for 20min to further refine the particles, and then pass ultra-high pressure homogenization Homogenize the slurry twice under the condition of pressure of 110mpa and temperature of 65°C, carry out nano-processing on the selenium-enriched yeast slurry, and then undergo centrifugal spray drying, rapid solidification, and granulation to prepare nano-organic selenium powder for future use. ;

[0039] Harvest commercially available food grade L-ascorbic acid, vitamin K2 (fermentation method), D-alpha-tocopheryl succinate, sorbitol, lactose, silicon dioxide, microcrystalline cellulose, povidone, magnesium stearate ,spare;

[0040] Weigh 157 parts of raw material n...

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Abstract

The invention discloses a nano organic selenium tablet, which is prepared from the following raw materials in parts by weight: 150 to 170 parts of nano organic selenium powder, 75 to 95 parts of L-ascorbic acid C, 25 to 35 parts of vitamin K2 (fermentation method), 20 to 30 parts of D-alpha-tocopherol succinate, 20 to 195 parts of sorbitol, 10 to 70 parts of lactose, 10 to 35 parts of silicon dioxide, microcrystalline cellulose, and 1 to 3 parts of povidone. The preparation method is characterized by comprising the following steps: weighing main and auxiliary materials according to a certain ratio, carrying out primary crushing and primary grinding and secondary fine grinding to guarantee that the particle size after fine grinding is not larger than 20 nanometer, carrying out boiling granulation after fine grinding, adding a lubricant, and carrying out total mixing, tabletting, coating and packaging. The adopted formula is scientific, the adopted nanocrystallization processing method is a pure physical method, no chemical reaction exists, substances in selenium yeast cells cannot be damaged, harmful substances cannot be brought in, and the selenium-enriched yeast is clean and environmentally friendly, so that the selenium-enriched yeast has the characteristics of being safe to eat, high in selenium content, good in taste, high in bioavailability and good in selenium supplementing effect.

Description

technical field [0001] The invention belongs to the technical field of food and medicine processing, in particular to a nano-organic selenium tablet and a preparation method thereof. Background technique [0002] Selenium is an essential trace element for human beings. However, the soil of selenium is extremely unevenly distributed on the earth's surface. About 72% of the soil in the world is deficient in selenium, which causes selenium deficiency in most people. Selenium deficiency will directly lead to the decline of human immunity. Clinical medicine has proved that more than 40 kinds of diseases that threaten human health and life are related to human selenium deficiency, such as cancer, cardiovascular disease, liver disease, cataract, pancreatic disease, diabetes, reproductive Systemic diseases and so on. According to expert research, people need selenium supplementation for life. Both animal experiments and clinical practice have shown that sufficient selenium should ...

Claims

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Application Information

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IPC IPC(8): A23L33/16A23L33/15A23L33/14A23L5/30A23P10/28
CPCA23L33/16A23L33/15A23L33/14A23L5/32A23L5/30A23P10/28A23V2002/00A23V2250/1626A23V2250/708A23V2250/7144A23V2250/712A23V2300/48A23V2300/46A23V2250/6422A23V2250/612A23V2250/1628A23V2250/51084A23V2250/76
Inventor 王治伦乔坤
Owner WEIHAI TERENCE BIO ENG
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