Preparation method and application of corn ACE (Angiotensin Converting Enzyme) inhibitory peptide-iron powder for supplementing iron and reducing blood pressure
A technology for inhibiting peptides and lowering blood pressure, which is applied in the field of preparation of iron-supplementing and lowering blood pressure corn ACE inhibitory peptide-iron powder, to achieve the effects of solving adverse side effects, increasing bioavailability, and improving symptoms
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Embodiment 1
[0031] The preparation method of iron supplement and blood pressure lowering corn ACE inhibitory peptide-iron powder is carried out according to the following steps:
[0032] (1) Preparation of ACE inhibitory peptide from corn: mix corn yellow powder with water, the ratio of corn yellow powder to water is 8g:100mL, heat for the first time, and adjust the pH value to 7.0 with 5M NaOH after heating to 50°C to get Mixed solution A; add neutral protease in mixed solution A, add according to the quality of corn yellow powder in mixed solution A, add enzyme amount to be 2000U / g, carry out 4000r / min centrifugal 10min after pre-enzymolysis time 2.5h, obtain The supernatant is filtered by an ultrafiltration device with an ultrafiltration membrane size of 30kDa to obtain corn preenzyme hydrolyzate A;
[0033] Then dilute the corn pre-enzymolysis solution A with water to obtain a diluted solution with a concentration of 10.86mg / mL, heat it for the second time, and use 5M NaOH to adjust t...
Embodiment 2
[0050] The preparation method is the same as in Example 1, except that the dosage ratio of ascorbic acid and corn ACE inhibitory peptide B is 0.5g:100mL, and the specific results are shown in Table 1.
Embodiment 3
[0052] The preparation method is the same as in Example 1, except that the dosage ratio of ascorbic acid and corn ACE inhibitory peptide B is 2.5g:100mL, and the specific results are shown in Table 1.
[0053] Table 1 Effect of different dosage ratios of ascorbic acid and corn ACE inhibitory peptide on chelation reaction
[0054] Example Dosage ratio (g:100mL) Iron content (%) Chelate Yield (%) Example 2 0.5 23.74 26.66 Example 1 2 33.63 40.73 Example 3 2.5 33.75 43.36
[0055] By analyzing Examples 1-3 in Table 1, it was found that both the iron content and the chelate yield increased with the increase of the dosage ratio of ascorbic acid and corn ACE inhibitory peptide. When the amount of ascorbic acid is small, the antioxidant protection effect is weak, ferrous ions are easily oxidized to ferric iron, and it is difficult to chelate with peptides, so that the iron content and yield of the product are not high. When the dosage of a...
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