Process for preparing film coated brain-invigorating kidney-tonifying pills

A technology of film coating and production method, which is applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, plant raw materials, etc., which can solve the problems affecting the quality of pills, workers' health, tissue prone to granuloma, and gastrointestinal irritation and other problems, to achieve the effects of chemical properties without physiological toxicity, less increase in pill weight, and less impact by heat

Active Publication Date: 2007-08-22
RONGCHANG PHARM ZIBO CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its disadvantages are: long operation time, high energy consumption, flying dust, serious environmental pollution, affecting the quality of pills and the health of workers
Its main coating materials are iron oxide red, talcum powder, starch, peach gum and sucrose, wherein the amount of talcum powder accounts for 18% of the weight of the pills. Talcum powder is a traditional Chinese medicine and is also commonly used as a coating material; The intestinal tract is irritating, and the tissues polluted by talcum powder are prone to granulomas. Long-term inhalation of talcum powder dust can cause pneumoconiosis. Long-term use is potentially harmful to health

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] 1. Make the core of Jiannaobukidney pills, and the drug dosage is as follows:

[0028] Ginseng 30g, deer antler 7g, dog whip 14g, cinnamon 30g, golden bull grass 12g, fried burdock seed 18g, golden cherry seed 12, Eucommia charcoal 36g, Sichuan Achyranthes bidentata 36g, honeysuckle 26g, forsythia 24g, cicada slough 24g, yam 48g, Polygala 42g, Suanzaoren 42g, Amomum 42g, Angelica 36g, Calcined keel 35g, Calcined oyster 42g, Poria cocos 84g, Stir-fried Atractylodes macrocephala 42g, Guizhi 35g, Licorice 28g, Stir-fried white peony root 35g, Cardamom 35g;

[0029] Wherein, described medicinal material refers to:

[0030] Ginseng Radix Ginseng, Deer Antler Cornu Cervi Pantotrichum, Dog Whip Penis Et Testis Canis, Cinnamon Cortex Cinnamomi, Golden Bull Grass (dried whole herb of Aleurito prerisargentea (Gmel) Fe'e), Arctium (fried) Fructus Arctii, Fructus Rosae Laevigatae, Cortex Eucommiae, Radix Cyathulae, Flos Lonicerae, Fructus Forsythiae, Periostracum Cicadae, Rhizoma ...

Embodiment 2

[0048] 1. Make the core of Jiannaobukidney pills, and the drug dosage is as follows:

[0049] 26.25g ginseng, 5.13g deer antler, 12.25g dog whip, 26.25g meat hanging, 10.5g golden bull grass, 15.75g fried burdock, 10.5g golden cherry, 31.5g Eucommia charcoal, 31.5g Sichuan achyranthes bidentata, 22.75g honeysuckle, Forsythia 21g, cicada slough 21g, Chinese yam 42g, polygala 36.75g, jujube seed 36.75g, amomum 36.75g, angelica 31.5g, calcined keel 30.65g, calcined oyster 36.75g, poria cocos 73.5g, fried Atractylodes macrocephala 36.75g, cassia twig 30.65g, licorice 24.5g, fried white peony root 30.65g, cardamom 30.65g.

[0050]2. Composition of film coating solution:

[0051] Hydroxypropyl Cellulose 19.6g

[0052] Titanium dioxide 20.0g

[0053] Red Yeast Powder 15.0g

[0054] Sunset Yellow Aluminum Lake 0.60g

[0055] 60% ethanol 600g

[0056] * Hydroxypropyl cellulose is also called hydroxypropyl cellulose (Hyprolose), low-substituted 2-hydroxypropyl ether cellulose; th...

Embodiment 3

[0058] 1. Make the core of Jiannaobukidney pills, and the drug dosage is as follows:

[0059] Ginseng 33.75g, deer antler 7.88g, dog whip 15.75g, cinnamon 33.75g, golden bull grass 13.5g, fried burdock seed 20.25g, golden cherry seed 13.5g, Eucommia charcoal 40.5g, Sichuan achyranthes bidentata 40.5g, honeysuckle 29.25g, even Alice 27g, cicada slough 27g, Chinese yam 54g, polygala 47.25g, jujube seed 47.25g, amomum 47.25g, angelica 40.5g, calcined keel 39.35g, calcined oyster 47.25g, poria cocos 94.5g, fried Atractylodes macrocephala 47.25g, cassia twig 39.35g g, licorice 31.5g, fried white peony root 39.35g, cardamom 39.35g.

[0060] 2. Composition of film coating solution:

[0061] Methylcellulose 24.5g

[0062] Talc powder 25.0g

[0063] Amaranth 18.15g

[0064] Sunset Yellow Aluminum Lake 0.60g

[0065] 90% ethanol 200g

[0066] Purified water 400g

[0067] * Methylcellulose is also known as methyl ether cellulose;

[0068] Dissolve or soak methylcellulose in etha...

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Abstract

The invention relates to a process for preparing film coated brain-invigorating kidney-tonifying pills, wherein the pills are prepared from the following Chinese medicinal herbs: gen-seng, hairy deerhorn, dog's penis, Cinnamomum cassia, lysimachia christinae, arctium fruit, cherokee rose, eucommia bark, achyranthes and cyathula root, honeysuckle flower, capsule of weeping forsythia, cicada shell, rhizoma dioscoreae, polygala root, wild jujuba seeds, amomum fruit, Chinese angelica root, dragon's bone, oyster shell, poria cocos, white atractylodes rhizome, cassia twig, licorice root, root of herbaceous peony and cardamorn.

Description

technical field [0001] The invention belongs to a coating process of pills, in particular to a method for preparing film-coated pills for strengthening the brain and nourishing the kidney. Background technique [0002] Jiannaobushen Pill is a Chinese patent medicine for strengthening the brain and kidney, nourishing qi and invigorating the spleen, calming the nerves and calming the mind (16 volumes of traditional Chinese medicine preparations). It was originally coated with cinnabar, and when the traditional Chinese medicine was rectified, it was colored with iron oxide red and coated with sugar. ,Still in use. Its disadvantages are: long operation time, high energy consumption, flying dust, serious environmental pollution, affecting the quality of pills and the health of workers. Its main coating materials are iron oxide red, talcum powder, starch, peach gum and sucrose, wherein the amount of talcum powder accounts for 18% of the weight of the pills. Talcum powder is a tra...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9064A61K36/8945A61K36/738A61K36/725A61K36/71A61K36/69A61K36/634A61K36/54A61K36/484A61K36/46A61K35/64A61K35/56A61P25/00A61P13/12
Inventor 郭桂秋陈树恩阚金健房国栋
Owner RONGCHANG PHARM ZIBO CO LTD
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