Azithromycin oral disintegration tablet and its preparing method
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- CSPC ZHONGQI PHARM TECH (SHIJIAZHUANG) CO LTD
- Publication Date
- 2005-01-12
Smart Images
Figure 1
Abstract
Description
technical field
[0001] The invention relates to an azithromycin orally disintegrating tablet and a preparation method thereof. technical background
[0002] Azithromycin is a macrolide antibiotic, which achieves antibacterial effect by inhibiting the synthesis of ribosomal 50S subunit protein in bacterial cells. Azithromycin can inhibit a variety of Gram-positive cocci, Mycoplasma, Chlamydia and Legionella pneumophila, especially has good antibacterial activity against some important Gram-negative bacilli such as Haemophilus influenzae. Azithromycin is widely used clinically in the treatment of respiratory tract infections, skin and soft tissue infections, and genitourinary system infections.
[0003] The structural formula of azithromycin is as follows
[0004]
[0005] Currently, the dosage forms of azithromycin in clinical use include ordinary tablets, capsules, suspensions, injections, granules, etc. Most of these oral dosage forms need to be ta...